Affinity Data by PubMed id=26512410

PubMed code 26512410

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50013915 (CHEMBL1081913) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor expressed in HEK293 cells after 30 mins by cAMP assay				J Med Chem 59: 3579-92 (2016) Article DOI: 10.1021/acs.jmedchem.5b01198 BindingDB Entry DOI: 10.7270/Q28C9Z54
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Mus musculus)	BDBM29080 (CHEMBL280065 \| N-oleoylethanolamine \| Oleamide MEA...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCO Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at mouse GPR119 receptor cotransformed in Saccharomyces cerevisiae cells after 4 hrs by fluorescent Fus1p-LacZ reporter gene assay				J Med Chem 59: 3579-92 (2016) Article DOI: 10.1021/acs.jmedchem.5b01198 BindingDB Entry DOI: 10.7270/Q28C9Z54
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50172073 (CHEMBL3809509) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor assessed as increase in cellular cAMP levels by HTRF assay				J Med Chem 59: 3579-92 (2016) Article DOI: 10.1021/acs.jmedchem.5b01198 BindingDB Entry DOI: 10.7270/Q28C9Z54
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50172072 (CHEMBL3809973) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor assessed as increase in cellular cAMP levels by HTRF assay				J Med Chem 59: 3579-92 (2016) Article DOI: 10.1021/acs.jmedchem.5b01198 BindingDB Entry DOI: 10.7270/Q28C9Z54
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50172071 (CHEMBL3809686) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor expressed in CHOK1 cells assessed as increase in cellular cAMP levels after 30 mins by HTRF assay				J Med Chem 59: 3579-92 (2016) Article DOI: 10.1021/acs.jmedchem.5b01198 BindingDB Entry DOI: 10.7270/Q28C9Z54
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50172070 (CHEMBL3810173) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor cotransformed in Saccharomyces cerevisiae cells after by fluorescent reporter gene assay				J Med Chem 59: 3579-92 (2016) Article DOI: 10.1021/acs.jmedchem.5b01198 BindingDB Entry DOI: 10.7270/Q28C9Z54
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50172069 (CHEMBL3809616) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor cotransformed in Saccharomyces cerevisiae cells after by fluorescent reporter gene assay				J Med Chem 59: 3579-92 (2016) Article DOI: 10.1021/acs.jmedchem.5b01198 BindingDB Entry DOI: 10.7270/Q28C9Z54
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50172072 (CHEMBL3809973) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor expressed in CHOK1 cells assessed as increase in cellular cAMP levels after 30 mins by HTRF assay				J Med Chem 59: 3579-92 (2016) Article DOI: 10.1021/acs.jmedchem.5b01198 BindingDB Entry DOI: 10.7270/Q28C9Z54
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%