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PubMed code 26513642

Compile data set for download or QSAR
Found 28 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499710
PNG
(CHEMBL516021)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1cccnc1)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C30H28N4O2/c1-2-36-30(35)28-26(33-24-13-5-3-6-14-24)19-27(22-11-9-17-31-20-22)34(25-15-7-4-8-16-25)29(28)23-12-10-18-32-21-23/h3-18,20-21,27,29,33H,2,19H2,1H3
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n/an/a 1.79E+3n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50277158
PNG
(3123L | CHEBI:17939 | CL-13900 | GNF-Pf-2016 | P-6...)
Show SMILES COc1ccc(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)n2cnc3c(ncnc23)N(C)C)cc1 |r|
Show InChI InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1
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n/an/a 2.45E+3n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499702
PNG
(CHEMBL3740370)
Show SMILES CCOC(=O)C1C(N(C(CC1=O)c1cccnc1)c1ccccc1)c1cccnc1
Show InChI InChI=1S/C24H23N3O3/c1-2-30-24(29)22-21(28)14-20(17-8-6-12-25-15-17)27(19-10-4-3-5-11-19)23(22)18-9-7-13-26-16-18/h3-13,15-16,20,22-23H,2,14H2,1H3
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n/an/a 8.04E+3n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499709
PNG
(CHEMBL3741560)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccc(C)cc1)c1ccccc1)Nc1ccc(C)cc1 |t:5|
Show InChI InChI=1S/C33H33N3O2/c1-4-38-33(37)31-29(35-26-17-13-23(2)14-18-26)22-30(25-10-6-5-7-11-25)36(27-19-15-24(3)16-20-27)32(31)28-12-8-9-21-34-28/h5-21,30,32,35H,4,22H2,1-3H3
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n/an/a 8.53E+3n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499705
PNG
(CHEMBL3741724)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1ccc(cc1)C#N)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C32H28N4O2/c1-2-38-32(37)30-28(35-26-11-5-3-6-12-26)20-29(24-17-15-23(21-33)16-18-24)36(27-13-7-4-8-14-27)31(30)25-10-9-19-34-22-25/h3-19,22,29,31,35H,2,20H2,1H3
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n/an/a 1.02E+4n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499712
PNG
(CHEMBL3741833)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccccc1)c1ccc(cc1)C#N)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C32H28N4O2/c1-2-38-32(37)30-28(35-25-11-5-3-6-12-25)21-29(24-18-16-23(22-33)17-19-24)36(26-13-7-4-8-14-26)31(30)27-15-9-10-20-34-27/h3-20,29,31,35H,2,21H2,1H3
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n/an/a 3.27E+4n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499707
PNG
(CHEMBL3741904)
Show SMILES OC1=CC(N(C(C1)c1cccnc1)c1ccccc1)c1cccnc1 |t:1|
Show InChI InChI=1S/C21H19N3O/c25-19-12-20(16-6-4-10-22-14-16)24(18-8-2-1-3-9-18)21(13-19)17-7-5-11-23-15-17/h1-12,14-15,20-21,25H,13H2
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n/an/a 3.63E+4n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499708
PNG
(CHEMBL3739649)
Show SMILES OC1=CC(N(C(C1)c1ccccn1)c1ccccc1)c1ccccn1 |t:1|
Show InChI InChI=1S/C21H19N3O/c25-17-14-20(18-10-4-6-12-22-18)24(16-8-2-1-3-9-16)21(15-17)19-11-5-7-13-23-19/h1-14,20-21,25H,15H2
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n/an/a 3.64E+4n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499706
PNG
(CHEMBL3740199)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1cc(OC)c(OC)c(OC)c1)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C34H35N3O5/c1-5-42-34(38)31-27(36-25-14-8-6-9-15-25)21-28(24-19-29(39-2)33(41-4)30(20-24)40-3)37(26-16-10-7-11-17-26)32(31)23-13-12-18-35-22-23/h6-20,22,28,32,36H,5,21H2,1-4H3
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n/an/a 4.30E+4n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499704
PNG
(CHEMBL3740158)
Show SMILES COC(=O)C1=C(CC(N(C1c1ccc(cc1)[N+]([O-])=O)c1ccccc1)c1ccc(cc1)[N+]([O-])=O)Nc1ccccc1 |t:4|
Show InChI InChI=1S/C31H26N4O6/c1-41-31(36)29-27(32-23-8-4-2-5-9-23)20-28(21-12-16-25(17-13-21)34(37)38)33(24-10-6-3-7-11-24)30(29)22-14-18-26(19-15-22)35(39)40/h2-19,28,30,32H,20H2,1H3
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n/an/a 6.88E+4n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499713
PNG
(CHEMBL3741344)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccs1)c1ccccc1)c1ccc(Br)cc1)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C30H27BrN2O2S/c1-2-35-30(34)28-25(32-23-10-5-3-6-11-23)20-26(21-15-17-22(31)18-16-21)33(24-12-7-4-8-13-24)29(28)27-14-9-19-36-27/h3-19,26,29,32H,2,20H2,1H3
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n/an/a 8.10E+4n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499701
PNG
(CHEMBL3741701)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccccc1)c1ccccn1)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C30H28N4O2/c1-2-36-30(35)28-26(33-22-13-5-3-6-14-22)21-27(24-17-9-11-19-31-24)34(23-15-7-4-8-16-23)29(28)25-18-10-12-20-32-25/h3-20,27,29,33H,2,21H2,1H3
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n/an/a 9.25E+4n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499703
PNG
(CHEMBL3740862)
Show SMILES CCOC(=O)C1C(N(C(CC1=O)c1ccccn1)c1ccccc1)c1ccccn1
Show InChI InChI=1S/C24H23N3O3/c1-2-30-24(29)22-21(28)16-20(18-12-6-8-14-25-18)27(17-10-4-3-5-11-17)23(22)19-13-7-9-15-26-19/h3-15,20,22-23H,2,16H2,1H3
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n/an/a 9.29E+4n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))		BDBM50499711
PNG
(CHEMBL3741419)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1ccc(Cl)cc1)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C31H28ClN3O2/c1-2-37-31(36)29-27(34-25-11-5-3-6-12-25)20-28(22-15-17-24(32)18-16-22)35(26-13-7-4-8-14-26)30(29)23-10-9-19-33-21-23/h3-19,21,28,30,34H,2,20H2,1H3
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n/an/a 9.82E+4n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499707
PNG
(CHEMBL3741904)
Show SMILES OC1=CC(N(C(C1)c1cccnc1)c1ccccc1)c1cccnc1 |t:1|
Show InChI InChI=1S/C21H19N3O/c25-19-12-20(16-6-4-10-22-14-16)24(18-8-2-1-3-9-18)21(13-19)17-7-5-11-23-15-17/h1-12,14-15,20-21,25H,13H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499704
PNG
(CHEMBL3740158)
Show SMILES COC(=O)C1=C(CC(N(C1c1ccc(cc1)[N+]([O-])=O)c1ccccc1)c1ccc(cc1)[N+]([O-])=O)Nc1ccccc1 |t:4|
Show InChI InChI=1S/C31H26N4O6/c1-41-31(36)29-27(32-23-8-4-2-5-9-23)20-28(21-12-16-25(17-13-21)34(37)38)33(24-10-6-3-7-11-24)30(29)22-14-18-26(19-15-22)35(39)40/h2-19,28,30,32H,20H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499701
PNG
(CHEMBL3741701)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccccc1)c1ccccn1)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C30H28N4O2/c1-2-36-30(35)28-26(33-22-13-5-3-6-14-22)21-27(24-17-9-11-19-31-24)34(23-15-7-4-8-16-23)29(28)25-18-10-12-20-32-25/h3-20,27,29,33H,2,21H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499711
PNG
(CHEMBL3741419)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1ccc(Cl)cc1)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C31H28ClN3O2/c1-2-37-31(36)29-27(34-25-11-5-3-6-12-25)20-28(22-15-17-24(32)18-16-22)35(26-13-7-4-8-14-26)30(29)23-10-9-19-33-21-23/h3-19,21,28,30,34H,2,20H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499705
PNG
(CHEMBL3741724)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1ccc(cc1)C#N)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C32H28N4O2/c1-2-38-32(37)30-28(35-26-11-5-3-6-12-26)20-29(24-17-15-23(21-33)16-18-24)36(27-13-7-4-8-14-27)31(30)25-10-9-19-34-22-25/h3-19,22,29,31,35H,2,20H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499710
PNG
(CHEMBL516021)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1cccnc1)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C30H28N4O2/c1-2-36-30(35)28-26(33-24-13-5-3-6-14-24)19-27(22-11-9-17-31-20-22)34(25-15-7-4-8-16-25)29(28)23-12-10-18-32-21-23/h3-18,20-21,27,29,33H,2,19H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499713
PNG
(CHEMBL3741344)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccs1)c1ccccc1)c1ccc(Br)cc1)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C30H27BrN2O2S/c1-2-35-30(34)28-25(32-23-10-5-3-6-11-23)20-26(21-15-17-22(31)18-16-21)33(24-12-7-4-8-13-24)29(28)27-14-9-19-36-27/h3-19,26,29,32H,2,20H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50277158
PNG
(3123L | CHEBI:17939 | CL-13900 | GNF-Pf-2016 | P-6...)
Show SMILES COc1ccc(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)n2cnc3c(ncnc23)N(C)C)cc1 |r|
Show InChI InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499708
PNG
(CHEMBL3739649)
Show SMILES OC1=CC(N(C(C1)c1ccccn1)c1ccccc1)c1ccccn1 |t:1|
Show InChI InChI=1S/C21H19N3O/c25-17-14-20(18-10-4-6-12-22-18)24(16-8-2-1-3-9-16)21(15-17)19-11-5-7-13-23-19/h1-14,20-21,25H,15H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499703
PNG
(CHEMBL3740862)
Show SMILES CCOC(=O)C1C(N(C(CC1=O)c1ccccn1)c1ccccc1)c1ccccn1
Show InChI InChI=1S/C24H23N3O3/c1-2-30-24(29)22-21(28)16-20(18-12-6-8-14-25-18)27(17-10-4-3-5-11-17)23(22)19-13-7-9-15-26-19/h3-15,20,22-23H,2,16H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499709
PNG
(CHEMBL3741560)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccc(C)cc1)c1ccccc1)Nc1ccc(C)cc1 |t:5|
Show InChI InChI=1S/C33H33N3O2/c1-4-38-33(37)31-29(35-26-17-13-23(2)14-18-26)22-30(25-10-6-5-7-11-25)36(27-19-15-24(3)16-20-27)32(31)28-12-8-9-21-34-28/h5-21,30,32,35H,4,22H2,1-3H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499706
PNG
(CHEMBL3740199)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1cc(OC)c(OC)c(OC)c1)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C34H35N3O5/c1-5-42-34(38)31-27(36-25-14-8-6-9-15-25)21-28(24-19-29(39-2)33(41-4)30(20-24)40-3)37(26-16-10-7-11-17-26)32(31)23-13-12-18-35-22-23/h6-20,22,28,32,36H,5,21H2,1-4H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499712
PNG
(CHEMBL3741833)
Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccccc1)c1ccc(cc1)C#N)Nc1ccccc1 |t:5|
Show InChI InChI=1S/C32H28N4O2/c1-2-38-32(37)30-28(35-25-11-5-3-6-12-25)21-29(24-18-16-23(22-33)17-19-24)36(26-13-7-4-8-14-26)31(30)27-15-9-10-20-34-27/h3-20,29,31,35H,2,21H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50499702
PNG
(CHEMBL3740370)
Show SMILES CCOC(=O)C1C(N(C(CC1=O)c1cccnc1)c1ccccc1)c1cccnc1
Show InChI InChI=1S/C24H23N3O3/c1-2-30-24(29)22-21(28)14-20(17-8-6-12-25-15-17)27(19-10-4-3-5-11-19)23(22)18-9-7-13-26-16-18/h3-13,15-16,20,22-23H,2,14H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins

Eur J Med Chem 106: 26-33 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.026
BindingDB Entry DOI: 10.7270/Q2FF3WCZ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%