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PubMed code 26525865

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM21008
PNG
((4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)pr...)
Show SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O
Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1
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MCE
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 13n/an/an/an/a



The University of Iowa

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor over-expressed in CHO cell membrane after 1 hr by [35S]GTPgammaS binding assay


Bioorg Med Chem Lett 25: 5532-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.059
BindingDB Entry DOI: 10.7270/Q2FN195J
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50499193
PNG
(CHEMBL3735897)
Show SMILES [#6]-[#8]-c1cc(-[#8]-[#6])c(-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c(\[#6]=[#6]\c2ccc(-[#8])c(-[#8])c2-[#6]\[#6]=[#6](\[#6])-[#6])c1
Show InChI InChI=1S/C31H40O4/c1-21(2)9-8-10-23(5)12-17-27-25(19-26(34-6)20-30(27)35-7)14-13-24-15-18-29(32)31(33)28(24)16-11-22(3)4/h9,11-15,18-20,32-33H,8,10,16-17H2,1-7H3/b14-13+,23-12+
PDB

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KEGG

UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 6.60E+3n/an/an/an/a



The University of Iowa

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor over-expressed in CHO cell membrane after 1 hr by [35S]GTPgammaS binding assay


Bioorg Med Chem Lett 25: 5532-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.059
BindingDB Entry DOI: 10.7270/Q2FN195J
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%