Affinity Data by PubMed id=26526213

PubMed code 26526213

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50133897 (CHEMBL3634267) Show SMILES Oc1ccc(\C=C2\Cc3ccccc3C2=O)cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase polyphenol oxidase activity using L-DOPA as substrate by Dixon plot analysis				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50133898 (CHEMBL3634266) Show SMILES Oc1ccc(\C=C2\Cc3ccccc3C2=O)c(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase polyphenol oxidase activity using L-DOPA as substrate by Dixon plot analysis				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase polyphenol oxidase activity using L-DOPA as substrate by Dixon plot analysis				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50133897 (CHEMBL3634267) Show SMILES Oc1ccc(\C=C2\Cc3ccccc3C2=O)cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50133898 (CHEMBL3634266) Show SMILES Oc1ccc(\C=C2\Cc3ccccc3C2=O)c(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%