Affinity Data by PubMed id=26562543

PubMed code 26562543

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM7398 ((2 Z)-6 -Bromoindirubin \| 6 -bromoindirubin \| 6-br...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Competitive inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 30 mins by scintillation counting analysis i...				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM7287 (8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octad...) Show SMILES O=C1Cc2c([nH]c3ccccc23)-c2ccccc2N1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Competitive inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 30 mins by scintillation counting analysis i...				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 (Homo sapiens (Human))	BDBM7262 (14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Inhibition of glycogen synthase kinase-3 (unknown origin)				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen synthase kinase-3 (Homo sapiens (Human))	BDBM7463 (4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazin-3-amine \|...) Show SMILES Nc1n[nH]c2nnc(-c3ccccc3)c(-c3ccccc3)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Inhibition of glycogen synthase kinase-3 (unknown origin)				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 (Homo sapiens (Human))	BDBM50135214 (CHEMBL3747661) Show SMILES COc1ccc(CNC(=O)Nc2nc(C)c(s2)C(C)=O)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Competitive inhibition of glycogen synthase kinase-3 (unknown origin) in presence of ATP				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM7876 (2-bromo-1-(4-bromophenyl)ethan-1-one \| Halomethyl ...) Show SMILES BrCC(=O)c1ccc(Br)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 20 mins by scintillation counting analysis in presence o...				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM7877 (2-bromo-1-(4-chlorophenyl)ethan-1-one \| Halomethyl...) Show SMILES Clc1ccc(cc1)C(=O)CBr Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 20 mins by scintillation counting analysis in presence o...				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 (Homo sapiens (Human))	BDBM50135211 (CHEMBL3747426) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Inhibition of glycogen synthase kinase-3 (unknown origin)				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50119691 (2-Bromo-1-(4-nitro-phenyl)-ethanone \| CHEMBL106072) Show SMILES [O-][N+](=O)c1ccc(cc1)C(=O)CBr Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 20 mins by scintillation counting analysis in presence o...				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM7874 (2-chloro-1-(4-chlorophenyl)ethan-1-one \| Halomethy...) Show SMILES ClCC(=O)c1ccc(Cl)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 20 mins by scintillation counting analysis in presence o...				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM7875 (2-bromo-1-phenylethan-1-one \| CHEMBL102953 \| Halom...) Show SMILES BrCC(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 20 mins by scintillation counting analysis in presence o...				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 (Homo sapiens (Human))	BDBM50135212 (CHEMBL3746095) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Inhibition of glycogen synthase kinase-3 (unknown origin)				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM7873 (2-chloro-1-phenylethan-1-one \| CHEMBL105712 \| Halo...) Show SMILES ClCC(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 20 mins by scintillation counting analysis in presence o...				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50134240 (CHEMBL3745772) Show SMILES BrCC(=O)c1ccc(cc1)C1C(=O)c2ccccc2C1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Central University Curated by ChEMBL					Assay Description Inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 20 mins by scintillation counting analysis in presence o...				Eur J Med Chem 107: 63-81 (2015) Article DOI: 10.1016/j.ejmech.2015.10.018 BindingDB Entry DOI: 10.7270/Q2TH8PH8
Central University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%