Affinity Data by PubMed id=26585276

PubMed code 26585276

Found 17 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM50308520 (CHEMBL603622 \| cyclophostin) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Irreversible inhibition of AChE (unknown origin)				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Musca domestica)	BDBM50308520 (CHEMBL603622 \| cyclophostin) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of housefly CSMA AChE				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50064426 (CHEMBL3401159) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 8				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50308520 (CHEMBL603622 \| cyclophostin) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 8				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50308520 (CHEMBL603622 \| cyclophostin) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of AChE (unknown origin)				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50499370 (CHEMBL3736339) Show SMILES COC(=O)C1=C(C)OP(=O)(OC)OCC1 \|c:4\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 8				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50499370 (CHEMBL3736339) Show SMILES COC(=O)C1=C(C)OP(=O)(OC)OCC1 \|c:4\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 6				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241989 (CHEMBL2179375) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 8				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50499368 (CHEMBL3735606) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 8				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50499368 (CHEMBL3735606) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 6				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50499367 (CHEMBL3735042) Show SMILES CCOP1(=O)CCCC(C(=O)OC)=C(C)O1 \|t:12\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 8				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50499367 (CHEMBL3735042) Show SMILES CCOP1(=O)CCCC(C(=O)OC)=C(C)O1 \|t:12\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 6				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50308515 (2-Methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-2lambd...) Show SMILES COC(=O)C1=C(C)OP(=O)(CCC1)OC \|c:4\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 8				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50308515 (2-Methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-2lambd...) Show SMILES COC(=O)C1=C(C)OP(=O)(CCC1)OC \|c:4\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 6				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241988 (CHEMBL592433) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 8				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50499369 (CHEMBL3734787) Show SMILES CCOP1(=O)OC(C)=C(CCC1(F)F)C(=O)OC \|c:7\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 6				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50499369 (CHEMBL3734787) Show SMILES CCOP1(=O)OC(C)=C(CCC1(F)F)C(=O)OC \|c:7\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE at pH 8				Bioorg Med Chem 23: 7529-34 (2015) Article DOI: 10.1016/j.bmc.2015.10.044 BindingDB Entry DOI: 10.7270/Q2N58QCW
University of Missouri-St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%