Affinity Data by PubMed id=26616289

PubMed code 26616289

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50299413 ((3',5'-dimethoxy-7-hydroxyisoflavone) \| CHEMBL5750...) Show SMILES COc1cc(OC)cc(c1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.46E+4	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha assessed as induction of transactivation activity by cell based assay				Bioorg Med Chem 23: 7676-84 (2015) Article DOI: 10.1016/j.bmc.2015.11.013 BindingDB Entry DOI: 10.7270/Q2319ZWJ
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50299416 (3'-methoxy-7-hydroxyisoflavone \| CHEMBL573966) Show SMILES COc1cccc(c1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.31E+4	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha assessed as induction of transactivation activity by cell based assay				Bioorg Med Chem 23: 7676-84 (2015) Article DOI: 10.1016/j.bmc.2015.11.013 BindingDB Entry DOI: 10.7270/Q2319ZWJ
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50299416 (3'-methoxy-7-hydroxyisoflavone \| CHEMBL573966) Show SMILES COc1cccc(c1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.23E+4	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma assessed as induction of transactivation activity by cell based assay				Bioorg Med Chem 23: 7676-84 (2015) Article DOI: 10.1016/j.bmc.2015.11.013 BindingDB Entry DOI: 10.7270/Q2319ZWJ
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50299413 ((3',5'-dimethoxy-7-hydroxyisoflavone) \| CHEMBL5750...) Show SMILES COc1cc(OC)cc(c1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma assessed as induction of transactivation activity by cell based assay				Bioorg Med Chem 23: 7676-84 (2015) Article DOI: 10.1016/j.bmc.2015.11.013 BindingDB Entry DOI: 10.7270/Q2319ZWJ
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50299415 (4'-fluoro-7-hydroxyisoflavone \| CHEMBL583378) Show SMILES Oc1ccc2c(c1)occ(-c1ccc(F)cc1)c2=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.31E+4	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha assessed as induction of transactivation activity by cell based assay				Bioorg Med Chem 23: 7676-84 (2015) Article DOI: 10.1016/j.bmc.2015.11.013 BindingDB Entry DOI: 10.7270/Q2319ZWJ
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50299414 (3-(benzo[d][1,3]dioxol-5-yl)-7-hydroxy-4H-chromen-...) Show SMILES Oc1ccc2c(c1)occ(-c1ccc3OCOc3c1)c2=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha assessed as induction of transactivation activity by cell based assay				Bioorg Med Chem 23: 7676-84 (2015) Article DOI: 10.1016/j.bmc.2015.11.013 BindingDB Entry DOI: 10.7270/Q2319ZWJ
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50299415 (4'-fluoro-7-hydroxyisoflavone \| CHEMBL583378) Show SMILES Oc1ccc2c(c1)occ(-c1ccc(F)cc1)c2=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.54E+4	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma assessed as induction of transactivation activity by cell based assay				Bioorg Med Chem 23: 7676-84 (2015) Article DOI: 10.1016/j.bmc.2015.11.013 BindingDB Entry DOI: 10.7270/Q2319ZWJ
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50299414 (3-(benzo[d][1,3]dioxol-5-yl)-7-hydroxy-4H-chromen-...) Show SMILES Oc1ccc2c(c1)occ(-c1ccc3OCOc3c1)c2=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.69E+4	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma assessed as induction of transactivation activity by cell based assay				Bioorg Med Chem 23: 7676-84 (2015) Article DOI: 10.1016/j.bmc.2015.11.013 BindingDB Entry DOI: 10.7270/Q2319ZWJ
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%