Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50199522 ((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian Normal University Curated by ChEMBL | Assay Description Inhibition of human acetylcholinesterase after 30 mins by microplate reader-based Ellman's method | J Nat Prod 78: 3067-70 (2015) Article DOI: 10.1021/acs.jnatprod.5b00600 BindingDB Entry DOI: 10.7270/Q2RX9DX7 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50141096 (CHEMBL3759013) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.49E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian Normal University Curated by ChEMBL | Assay Description Inhibition of human acetylcholinesterase after 30 mins by microplate reader-based Ellman's method | J Nat Prod 78: 3067-70 (2015) Article DOI: 10.1021/acs.jnatprod.5b00600 BindingDB Entry DOI: 10.7270/Q2RX9DX7 | |||||||||||
More data for this Ligand-Target Pair |