Affinity Data by PubMed id=26639764

PubMed code 26639764

Found 17 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50138810 (CHEMBL3752558) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138812 (CHEMBL3754172) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138811 (CHEMBL3753294) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138807 (CHEMBL3752979) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138804 (CHEMBL3752524) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.19E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138803 (CHEMBL3752412) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.33E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138809 (CHEMBL3754062) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.68E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138817 (CHEMBL3752507) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.94E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50420190 (5052 \| ACETYLCYSTEINE) Show SMILES CC(=O)N[C@@H](CS)C(O)=O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138814 (CHEMBL3752230) Show SMILES CCCCCNC(=S)SC[C@H](NC(C)=O)C(O)=O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138815 (CHEMBL3753774) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.44E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138816 (CHEMBL3752846) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.45E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138813 (CHEMBL3754758) Show SMILES CCCCNC(=S)SC[C@H](NC(C)=O)C(O)=O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.46E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138808 (CHEMBL3754699) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.74E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138806 (CHEMBL3752941) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.26E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138805 (CHEMBL3754532) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.37E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50138802 (CHEMBL3752573) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.96E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...				Bioorg Med Chem Lett 26: 667-71 (2016) Article DOI: 10.1016/j.bmcl.2015.11.045 BindingDB Entry DOI: 10.7270/Q2D220G2
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%