Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Inhibition of human ERG | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134444![]() (CHEMBL3747085) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 186 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134446![]() (CHEMBL3747597) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 759 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134455![]() (CHEMBL3747522) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 490 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134440![]() (CHEMBL3745940) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 760 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134463![]() (CHEMBL3747012) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 690 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134465![]() (CHEMBL3746325) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 91 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in HEK293 cells by [35S]-GTPgammaS binding assay | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134479![]() (CHEMBL3745901) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 158 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134480![]() (CHEMBL3746731) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134438![]() (CHEMBL3747073) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 71 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134440![]() (CHEMBL3745940) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 759 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134445![]() (CHEMBL3746298) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 617 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134474![]() (CHEMBL3746294) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134476![]() (CHEMBL3746299) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | <3.02E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134480![]() (CHEMBL3746731) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134437![]() (CHEMBL3746591) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 87 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134438![]() (CHEMBL3747073) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 71 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134449![]() (CHEMBL3745812) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134457![]() (CHEMBL3746779) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50134466![]() (CHEMBL3747116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu1 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50134466![]() (CHEMBL3747116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat)) | BDBM50134443![]() (CHEMBL3746457) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of rat mGlu6 receptor expressed in CHO cells by [35S]-GTPgammaS binding assay | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134441![]() (CHEMBL3746240) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.09E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134442![]() (CHEMBL3747717) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.09E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134457![]() (CHEMBL3746779) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134453![]() (CHEMBL3746604) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134468![]() (CHEMBL3747072) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.76E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134476![]() (CHEMBL3746299) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.76E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Homo sapiens (Human)) | BDBM50134466![]() (CHEMBL3747116) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in L929sA cells by [35S]-GTPgammaS binding assay | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134463![]() (CHEMBL3747012) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 692 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134466![]() (CHEMBL3747116) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 158 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134468![]() (CHEMBL3747072) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.76E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134473![]() (CHEMBL3747078) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.82E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134439![]() (CHEMBL3747662) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134441![]() (CHEMBL3746240) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.09E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134442![]() (CHEMBL3747717) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.09E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134444![]() (CHEMBL3747085) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134455![]() (CHEMBL3747522) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 490 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134466![]() (CHEMBL3747116) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134467![]() (CHEMBL3747260) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134466![]() (CHEMBL3747116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.39E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 8 (Homo sapiens (Human)) | BDBM50134466![]() (CHEMBL3747116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu8 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134448![]() (CHEMBL3747118) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134467![]() (CHEMBL3747260) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | <3.02E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134469![]() (CHEMBL3746344) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 540 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 8 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu8 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50134466![]() (CHEMBL3747116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in L929sA cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat)) | BDBM50134466![]() (CHEMBL3747116) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of rat mGlu6 receptor expressed in CHO cells by [35S]-GTPgammaS binding assay | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134447![]() (CHEMBL3747433) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 148 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134465![]() (CHEMBL3746325) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 91 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134469![]() (CHEMBL3746344) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 87 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134446![]() (CHEMBL3747597) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 760 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134447![]() (CHEMBL3747433) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134469![]() (CHEMBL3746344) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 87.1 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50134466![]() (CHEMBL3747116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134437![]() (CHEMBL3746591) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 87 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134449![]() (CHEMBL3745812) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 105 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134464![]() (CHEMBL3747732) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134479![]() (CHEMBL3745901) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134435![]() (CHEMBL3747735) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 65 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134445![]() (CHEMBL3746298) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 620 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134448![]() (CHEMBL3747118) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134438![]() (CHEMBL3747073) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in L929sA cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134435![]() (CHEMBL3747735) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 65 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134436![]() (CHEMBL3746540) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134439![]() (CHEMBL3747662) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 115 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134453![]() (CHEMBL3746604) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 302 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134436![]() (CHEMBL3746540) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134464![]() (CHEMBL3747732) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134473![]() (CHEMBL3747078) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.81E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50134474![]() (CHEMBL3746294) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134435![]() (CHEMBL3747735) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 74 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134449![]() (CHEMBL3745812) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134455![]() (CHEMBL3747522) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 290 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu1 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50134443![]() (CHEMBL3746457) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50134466![]() (CHEMBL3747116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in HEK293 cells by [35S]-GTPgammaS binding assay | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50134466![]() (CHEMBL3747116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in L929sA cells by [35S]-GTPgammaS binding assay | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair |