Affinity Data by PubMed id=26706352

PubMed code 26706352

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50142632 (CHEMBL1231469) Show SMILES Brc1ccc2NC(=O)\C(=C3/Nc4ccccc4C3=O)c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Egyptian Russian University Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant human CDK2/cyclin E expressed in insect SF-9 cells after 10 mins by scintillation counting analysis in presence ...				Eur J Med Chem 108: 415-22 (2016) Article DOI: 10.1016/j.ejmech.2015.11.047 BindingDB Entry DOI: 10.7270/Q2M90BJM
Egyptian Russian University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50310357 (CHEMBL599552 \| indigo) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Egyptian Russian University Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant human CDK2/cyclin E expressed in insect SF-9 cells after 10 mins by scintillation counting analysis in presence ...				Eur J Med Chem 108: 415-22 (2016) Article DOI: 10.1016/j.ejmech.2015.11.047 BindingDB Entry DOI: 10.7270/Q2M90BJM
Egyptian Russian University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%