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PubMed code 26771709

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix protein 2


(Influenza A virus (A/Udorn/307/1972(H3N2)))
BDBM50500845
PNG
(3-Azoniaspiro[5.5]Undecane Chloride | CHEMBL204131...)
Show SMILES Cl.C1CCC2(CC1)CCNCC2
Show InChI InChI=1S/C10H19N/c1-2-4-10(5-3-1)6-8-11-9-7-10/h11H,1-9H2
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PC sid
UniChem
Article
PubMed
n/an/a 900n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus wild type M2 proton channel infected in Xenopus laevis oocytes after 2 mins by TEVC assay


J Med Chem 59: 1207-16 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01910
BindingDB Entry DOI: 10.7270/Q2988B1S
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus (A/Udorn/307/1972(H3N2)))
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2 |THB:6:5:2:8.7.9,6:7:4.5.10:2,9:7:4:10.1.2,9:1:4:8.6.7,0:1:4:8.6.7|
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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MCE
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Article
PubMed
n/an/a 1.61E+4n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus wild type M2 proton channel infected in Xenopus laevis oocytes after 2 mins by TEVC assay


J Med Chem 59: 1207-16 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01910
BindingDB Entry DOI: 10.7270/Q2988B1S
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus (A/Udorn/307/1972(H3N2)))
BDBM50500846
PNG
(CHEMBL3770480)
Show SMILES NC1CCC2(CC1)C1CC3CC(C1)CC2C3 |THB:4:7:10:13.14.15,4:14:10:8.12.7,13:11:8:4.14.15,13:14:8:10.11.12|
Show InChI InChI=1S/C15H25N/c16-14-1-3-15(4-2-14)12-6-10-5-11(8-12)9-13(15)7-10/h10-14H,1-9,16H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.87E+4n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus wild type M2 proton channel infected in Xenopus laevis oocytes after 2 mins by TEVC assay


J Med Chem 59: 1207-16 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01910
BindingDB Entry DOI: 10.7270/Q2988B1S
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%