Affinity Data by PubMed id=26786695

PubMed code 26786695

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50143184 (CHEMBL3759063) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase activity using pBR322 DNA as substrate after 30 mins by fluorescence polarization assay				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50143186 (CHEMBL3759862) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase activity using pBR322 DNA as substrate after 30 mins by fluorescence polarization assay				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50143185 (CHEMBL3759272) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase activity using pBR322 DNA as substrate after 30 mins by fluorescence polarization assay				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50143184 (CHEMBL3759063) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to full length Staphylococcus aureus GyrB by STD-NMR spectroscopic analysis				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50449136 (CHEMBL288959) Show SMILES Nc1nc(cc(=O)[nH]1)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to full length Staphylococcus aureus GyrB by STD-NMR spectroscopic analysis				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50143186 (CHEMBL3759862) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to full length Staphylococcus aureus GyrB by STD-NMR spectroscopic analysis				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50143189 (CHEMBL3759276) Show SMILES CCCC(=O)Nc1sccc1C(N)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to full length Staphylococcus aureus GyrB by STD-NMR spectroscopic analysis				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50414094 (CHEMBL559696) Show SMILES O=c1[nH]cnc2scc(-c3cccs3)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to full length Staphylococcus aureus GyrB by STD-NMR spectroscopic analysis				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50143185 (CHEMBL3759272) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to full length Staphylococcus aureus GyrB by STD-NMR spectroscopic analysis				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50143187 (CHEMBL1481051) Show SMILES Cc1n[nH]c2NC(=O)CC(c12)c1ccccc1F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to full length Staphylococcus aureus GyrB by STD-NMR spectroscopic analysis				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50143188 (CHEMBL1419183) Show SMILES Cc1cc(O)[nH]c2nnc(-c3ccccc3)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to full length Staphylococcus aureus GyrB by STD-NMR spectroscopic analysis				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50143190 (CHEMBL3760057) Show SMILES O=C1Nc2ccccc2\C1=C/c1cccnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	8.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to full length Staphylococcus aureus GyrB by STD-NMR spectroscopic analysis				Bioorg Med Chem Lett 26: 1314-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.009 BindingDB Entry DOI: 10.7270/Q2XK8HDG
Cubist Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%