Found 23 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50133817
(4-(3-Chloro-pyridin-2-yl)-piperazine-1-carboxylic ...)Show SMILES CC(C)(C)c1ccc(NC(=O)N2CCN(CC2)c2ncccc2Cl)cc1 Show InChI InChI=1S/C20H25ClN4O/c1-20(2,3)15-6-8-16(9-7-15)23-19(26)25-13-11-24(12-14-25)18-17(21)5-4-10-22-18/h4-10H,11-14H2,1-3H3,(H,23,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500658
(CHEMBL3753419)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N1CCN(CC1)C(=O)Nc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C28H39N3O2/c1-20(2)19-22-7-9-23(10-8-22)21(3)26(32)30-15-17-31(18-16-30)27(33)29-25-13-11-24(12-14-25)28(4,5)6/h7-14,20-21H,15-19H2,1-6H3,(H,29,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500673
(CHEMBL3753666)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)NCCNC(=O)Nc1cc(Cl)ccc1Cl Show InChI InChI=1S/C22H27Cl2N3O2/c1-14(2)12-16-4-6-17(7-5-16)15(3)21(28)25-10-11-26-22(29)27-20-13-18(23)8-9-19(20)24/h4-9,13-15H,10-12H2,1-3H3,(H,25,28)(H2,26,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500668
(CHEMBL3753876)Show SMILES COc1cccc(NC(=O)CCCNC(=O)C(C)c2ccc(CC(C)C)cc2)c1 Show InChI InChI=1S/C24H32N2O3/c1-17(2)15-19-10-12-20(13-11-19)18(3)24(28)25-14-6-9-23(27)26-21-7-5-8-22(16-21)29-4/h5,7-8,10-13,16-18H,6,9,14-15H2,1-4H3,(H,25,28)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500661
(CHEMBL3754605)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)NCCCC(=O)Nc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C27H38N2O2/c1-19(2)18-21-9-11-22(12-10-21)20(3)26(31)28-17-7-8-25(30)29-24-15-13-23(14-16-24)27(4,5)6/h9-16,19-20H,7-8,17-18H2,1-6H3,(H,28,31)(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500665
(CHEMBL3752865)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C29H40N2O2/c1-20(2)19-22-7-9-23(10-8-22)21(3)28(33)31-17-15-24(16-18-31)27(32)30-26-13-11-25(12-14-26)29(4,5)6/h7-14,20-21,24H,15-19H2,1-6H3,(H,30,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500655
(CHEMBL3753349)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N1CCC(CC1)C(=O)Nc1ccccc1Cl Show InChI InChI=1S/C25H31ClN2O2/c1-17(2)16-19-8-10-20(11-9-19)18(3)25(30)28-14-12-21(13-15-28)24(29)27-23-7-5-4-6-22(23)26/h4-11,17-18,21H,12-16H2,1-3H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500667
(CHEMBL3752411)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)NCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C23H30N2O2/c1-17(2)16-19-11-13-20(14-12-19)18(3)23(27)24-15-7-10-22(26)25-21-8-5-4-6-9-21/h4-6,8-9,11-14,17-18H,7,10,15-16H2,1-3H3,(H,24,27)(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500672
(CHEMBL3753757)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N1CCC(CC1)C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C25H31ClN2O2/c1-17(2)15-19-7-9-20(10-8-19)18(3)25(30)28-13-11-21(12-14-28)24(29)27-23-6-4-5-22(26)16-23/h4-10,16-18,21H,11-15H2,1-3H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500662
(CHEMBL3754697)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)NCCCC(=O)Nc1ccc(N)cc1 Show InChI InChI=1S/C23H31N3O2/c1-16(2)15-18-6-8-19(9-7-18)17(3)23(28)25-14-4-5-22(27)26-21-12-10-20(24)11-13-21/h6-13,16-17H,4-5,14-15,24H2,1-3H3,(H,25,28)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 127 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500656
(CHEMBL3751973)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N1CCC(CC1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C25H31ClN2O2/c1-17(2)16-19-4-6-20(7-5-19)18(3)25(30)28-14-12-21(13-15-28)24(29)27-23-10-8-22(26)9-11-23/h4-11,17-18,21H,12-16H2,1-3H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500663
(CHEMBL3753519)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)NCCCC(=O)Nc1ccccc1N Show InChI InChI=1S/C23H31N3O2/c1-16(2)15-18-10-12-19(13-11-18)17(3)23(28)25-14-6-9-22(27)26-21-8-5-4-7-20(21)24/h4-5,7-8,10-13,16-17H,6,9,14-15,24H2,1-3H3,(H,25,28)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 173 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500669
(CHEMBL3752193)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)NCCCC(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C23H29ClN2O2/c1-16(2)15-18-6-8-19(9-7-18)17(3)23(28)25-14-4-5-22(27)26-21-12-10-20(24)11-13-21/h6-13,16-17H,4-5,14-15H2,1-3H3,(H,25,28)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 239 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500657
(CHEMBL3752106)Show SMILES COc1ccc(NC(=O)C2CCN(CC2)C(=O)C(C)c2ccc(CC(C)C)cc2)c(c1)[N+]([O-])=O Show InChI InChI=1S/C26H33N3O5/c1-17(2)15-19-5-7-20(8-6-19)18(3)26(31)28-13-11-21(12-14-28)25(30)27-23-10-9-22(34-4)16-24(23)29(32)33/h5-10,16-18,21H,11-15H2,1-4H3,(H,27,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 325 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500666
(CHEMBL3754239)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N1CCC(CC1)C(=O)Nc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C25H31N3O4/c1-17(2)16-19-8-10-20(11-9-19)18(3)25(30)27-14-12-21(13-15-27)24(29)26-22-6-4-5-7-23(22)28(31)32/h4-11,17-18,21H,12-16H2,1-3H3,(H,26,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 347 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500664
(CHEMBL3752745)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C25H31N3O4/c1-17(2)16-19-4-6-20(7-5-19)18(3)25(30)27-14-12-21(13-15-27)24(29)26-22-8-10-23(11-9-22)28(31)32/h4-11,17-18,21H,12-16H2,1-3H3,(H,26,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 359 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500659
(CHEMBL3752744)Show SMILES COc1ccccc1NC(=O)CCCNC(=O)C(C)c1ccc(CC(C)C)cc1 Show InChI InChI=1S/C24H32N2O3/c1-17(2)16-19-11-13-20(14-12-19)18(3)24(28)25-15-7-10-23(27)26-21-8-5-6-9-22(21)29-4/h5-6,8-9,11-14,17-18H,7,10,15-16H2,1-4H3,(H,25,28)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500652
(CHEMBL3753376)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)NCCCC(=O)Nc1cc(Cl)ccc1C Show InChI InChI=1S/C24H31ClN2O2/c1-16(2)14-19-8-10-20(11-9-19)18(4)24(29)26-13-5-6-23(28)27-22-15-21(25)12-7-17(22)3/h7-12,15-16,18H,5-6,13-14H2,1-4H3,(H,26,29)(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 381 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500660
(CHEMBL3753090)Show SMILES CCc1ccccc1NC(=O)CCCNC(=O)C(C)c1ccc(CC(C)C)cc1 Show InChI InChI=1S/C25H34N2O2/c1-5-21-9-6-7-10-23(21)27-24(28)11-8-16-26-25(29)19(4)22-14-12-20(13-15-22)17-18(2)3/h6-7,9-10,12-15,18-19H,5,8,11,16-17H2,1-4H3,(H,26,29)(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 403 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500654
(CHEMBL3753618)Show SMILES COc1ccccc1NC(=O)C1CCN(CC1)C(=O)C(C)c1ccc(CC(C)C)cc1 Show InChI InChI=1S/C26H34N2O3/c1-18(2)17-20-9-11-21(12-10-20)19(3)26(30)28-15-13-22(14-16-28)25(29)27-23-7-5-6-8-24(23)31-4/h5-12,18-19,22H,13-17H2,1-4H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 549 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500653
(CHEMBL3753679)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N1CCC(CC1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C25H32N2O2/c1-18(2)17-20-9-11-21(12-10-20)19(3)25(29)27-15-13-22(14-16-27)24(28)26-23-7-5-4-6-8-23/h4-12,18-19,22H,13-17H2,1-3H3,(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 591 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500671
(CHEMBL3753061)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N1CCC(CC1)C(=O)Nc1ccccc1C Show InChI InChI=1S/C26H34N2O2/c1-18(2)17-21-9-11-22(12-10-21)20(4)26(30)28-15-13-23(14-16-28)25(29)27-24-8-6-5-7-19(24)3/h5-12,18,20,23H,13-17H2,1-4H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 653 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50500670
(CHEMBL3753476)Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N1CCC(CC1)C(=O)Nc1ccc(C)cc1 Show InChI InChI=1S/C26H34N2O2/c1-18(2)17-21-7-9-22(10-8-21)20(4)26(30)28-15-13-23(14-16-28)25(29)27-24-11-5-19(3)6-12-24/h5-12,18,20,23H,13-17H2,1-4H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 783 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description
Antagonist activity at capsaicin-stimulated human TRPV1 receptor in aequorin expressing cells preincubated for 2.5 mins followed by capsaicin additio... |
Bioorg Med Chem 24: 849-57 (2016)
Article DOI: 10.1016/j.bmc.2016.01.009
BindingDB Entry DOI: 10.7270/Q2C53PVC |
More data for this
Ligand-Target Pair | |
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