Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50235980 (2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Milano Curated by ChEMBL | Assay Description Displacement of biotinylated ECM from human placental integrin alphavbeta3 receptor incubated for 3 hrs | Bioorg Med Chem 24: 989-94 (2016) Article DOI: 10.1016/j.bmc.2016.01.023 BindingDB Entry DOI: 10.7270/Q2KP854P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50500744 (CHEMBL3754095) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 221 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Milano Curated by ChEMBL | Assay Description Displacement of 125-I-echistatin from human placental integrin alphavbeta3 receptor incubated for 3 hrs by microplate scintillation counting analysis | Bioorg Med Chem 24: 989-94 (2016) Article DOI: 10.1016/j.bmc.2016.01.023 BindingDB Entry DOI: 10.7270/Q2KP854P | |||||||||||
More data for this Ligand-Target Pair |