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PubMed code 26824128

Compile data set for download or QSAR
Found 5 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50031467
PNG
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Show SMILES OCc1cc(=O)c(O)co1
Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
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Article
PubMed
n/an/a 4.60E+4n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric method


J Nat Prod 79: 447-50 (2016)


Article DOI: 10.1021/acs.jnatprod.5b00972
BindingDB Entry DOI: 10.7270/Q2G73GNT
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50219502
PNG
(4-hydroxyphenyl beta-D-glucopyranoside | Arbutin |...)
Show SMILES OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1
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PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric method


J Nat Prod 79: 447-50 (2016)


Article DOI: 10.1021/acs.jnatprod.5b00972
BindingDB Entry DOI: 10.7270/Q2G73GNT
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50168143
PNG
(CHEMBL3805523)
Show SMILES CCCCCCCCCC(=O)N\C(=C/c1ccc(O)cc1)C(O)=O
Show InChI InChI=1S/C19H27NO4/c1-2-3-4-5-6-7-8-9-18(22)20-17(19(23)24)14-15-10-12-16(21)13-11-15/h10-14,21H,2-9H2,1H3,(H,20,22)(H,23,24)/b17-14-
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n/an/a 1.30E+5n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric method


J Nat Prod 79: 447-50 (2016)


Article DOI: 10.1021/acs.jnatprod.5b00972
BindingDB Entry DOI: 10.7270/Q2G73GNT
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50168145
PNG
(CHEMBL3805142)
Show SMILES CCCCCCCCC(=O)N\C(=C/c1ccc(O)cc1)C(O)=O
Show InChI InChI=1S/C18H25NO4/c1-2-3-4-5-6-7-8-17(21)19-16(18(22)23)13-14-9-11-15(20)12-10-14/h9-13,20H,2-8H2,1H3,(H,19,21)(H,22,23)/b16-13-
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n/an/a 2.80E+5n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric method


J Nat Prod 79: 447-50 (2016)


Article DOI: 10.1021/acs.jnatprod.5b00972
BindingDB Entry DOI: 10.7270/Q2G73GNT
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50168144
PNG
(CHEMBL3806298)
Show SMILES CC(C)CCCCCCC(=O)N\C(=C/c1ccc(O)cc1)C(O)=O
Show InChI InChI=1S/C19H27NO4/c1-14(2)7-5-3-4-6-8-18(22)20-17(19(23)24)13-15-9-11-16(21)12-10-15/h9-14,21H,3-8H2,1-2H3,(H,20,22)(H,23,24)/b17-13-
UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 4.70E+5n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric method


J Nat Prod 79: 447-50 (2016)


Article DOI: 10.1021/acs.jnatprod.5b00972
BindingDB Entry DOI: 10.7270/Q2G73GNT
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%