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PubMed code 26851835

Compile data set for download or QSAR
Found 15 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150651
PNG
(CHEMBL3769527)
Show SMILES Clc1ccc(CNC(=O)Cn2cccc(NCc3ccc(Cl)c(Cl)c3)c2=O)cc1Cl
Show InChI InChI=1S/C21H17Cl4N3O2/c22-15-5-3-13(8-17(15)24)10-26-19-2-1-7-28(21(19)30)12-20(29)27-11-14-4-6-16(23)18(25)9-14/h1-9,26H,10-12H2,(H,27,29)
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PubMed
n/an/a 1.92E+3n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150650
PNG
(CHEMBL3769814)
Show SMILES Clc1ccc(CNc2cccn(CC(=O)NCc3ccc(Cl)c(Cl)c3)c2=O)cc1
Show InChI InChI=1S/C21H18Cl3N3O2/c22-16-6-3-14(4-7-16)11-25-19-2-1-9-27(21(19)29)13-20(28)26-12-15-5-8-17(23)18(24)10-15/h1-10,25H,11-13H2,(H,26,28)
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PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150653
PNG
(CHEMBL3770692)
Show SMILES [O-][N+](=O)c1ccc(CNc2cccn(CC(=O)NCc3ccc(Cl)c(Cl)c3)c2=O)cc1
Show InChI InChI=1S/C21H18Cl2N4O4/c22-17-8-5-15(10-18(17)23)12-25-20(28)13-26-9-1-2-19(21(26)29)24-11-14-3-6-16(7-4-14)27(30)31/h1-10,24H,11-13H2,(H,25,28)
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n/an/a 2.50E+3n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150645
PNG
(CHEMBL3771019)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1cccc1CNc1cccn(CC(=O)NCc2ccc(Cl)c(Cl)c2)c1=O
Show InChI InChI=1S/C26H24Cl2N4O4S/c1-18-6-9-21(10-7-18)37(35,36)32-13-2-4-20(32)16-29-24-5-3-12-31(26(24)34)17-25(33)30-15-19-8-11-22(27)23(28)14-19/h2-14,29H,15-17H2,1H3,(H,30,33)
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n/an/a 3.40E+3n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150649
PNG
(CHEMBL3770266)
Show SMILES Clc1cccc(CNc2cccn(CC(=O)NCc3ccc(Cl)c(Cl)c3)c2=O)c1
Show InChI InChI=1S/C21H18Cl3N3O2/c22-16-4-1-3-14(9-16)11-25-19-5-2-8-27(21(19)29)13-20(28)26-12-15-6-7-17(23)18(24)10-15/h1-10,25H,11-13H2,(H,26,28)
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PubMed
n/an/a 5.66E+3n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150640
PNG
(CHEMBL3769711)
Show SMILES Clc1ccc(CNc2cccn(CC(=O)NCc3ccccc3)c2=O)cc1Cl
Show InChI InChI=1S/C21H19Cl2N3O2/c22-17-9-8-16(11-18(17)23)13-24-19-7-4-10-26(21(19)28)14-20(27)25-12-15-5-2-1-3-6-15/h1-11,24H,12-14H2,(H,25,27)
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PubMed
n/an/a 1.02E+4n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150654
PNG
(CHEMBL3771162)
Show SMILES Clc1ccc(NC(=O)Cn2cccc(NC(=O)c3ccccc3)c2=O)cc1Cl
Show InChI InChI=1S/C20H15Cl2N3O3/c21-15-9-8-14(11-16(15)22)23-18(26)12-25-10-4-7-17(20(25)28)24-19(27)13-5-2-1-3-6-13/h1-11H,12H2,(H,23,26)(H,24,27)
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PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150648
PNG
(CHEMBL3769802)
Show SMILES Clc1ccc(CNC(=O)Cn2cccc(NCc3ccccc3Cl)c2=O)cc1Cl
Show InChI InChI=1S/C21H18Cl3N3O2/c22-16-5-2-1-4-15(16)12-25-19-6-3-9-27(21(19)29)13-20(28)26-11-14-7-8-17(23)18(24)10-14/h1-10,25H,11-13H2,(H,26,28)
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n/an/a 1.85E+4n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150655
PNG
(CHEMBL3770242)
Show SMILES Clc1ccc(CNc2cccn(CC(=O)Nc3ccc(Cl)c(Cl)c3)c2=O)cc1Cl
Show InChI InChI=1S/C20H15Cl4N3O2/c21-14-5-3-12(8-16(14)23)10-25-18-2-1-7-27(20(18)29)11-19(28)26-13-4-6-15(22)17(24)9-13/h1-9,25H,10-11H2,(H,26,28)
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n/an/a 1.85E+4n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150644
PNG
(CHEMBL3769650)
Show SMILES Clc1ccc(CNC(=O)Cn2cccc(NCc3cccs3)c2=O)cc1Cl
Show InChI InChI=1S/C19H17Cl2N3O2S/c20-15-6-5-13(9-16(15)21)10-23-18(25)12-24-7-1-4-17(19(24)26)22-11-14-3-2-8-27-14/h1-9,22H,10-12H2,(H,23,25)
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n/an/a 1.95E+4n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150656
PNG
(CHEMBL3770080)
Show SMILES Clc1ccc(CCNC(=O)Cn2cccc(NCc3ccc(Cl)c(Cl)c3)c2=O)cc1Cl
Show InChI InChI=1S/C22H19Cl4N3O2/c23-16-5-3-14(10-18(16)25)7-8-27-21(30)13-29-9-1-2-20(22(29)31)28-12-15-4-6-17(24)19(26)11-15/h1-6,9-11,28H,7-8,12-13H2,(H,27,30)
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n/an/a 2.25E+4n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150642
PNG
(CHEMBL3771282)
Show SMILES Clc1ccc(CNc2cccn(CC(=O)NCCc3ccccc3)c2=O)cc1Cl
Show InChI InChI=1S/C22H21Cl2N3O2/c23-18-9-8-17(13-19(18)24)14-26-20-7-4-12-27(22(20)29)15-21(28)25-11-10-16-5-2-1-3-6-16/h1-9,12-13,26H,10-11,14-15H2,(H,25,28)
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n/an/a 3.13E+4n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150652
PNG
(CHEMBL3769992)
Show SMILES Clc1ccc(NC(=O)Cn2cccc(NCc3ccccc3Cl)c2=O)cc1Cl
Show InChI InChI=1S/C20H16Cl3N3O2/c21-15-5-2-1-4-13(15)11-24-18-6-3-9-26(20(18)28)12-19(27)25-14-7-8-16(22)17(23)10-14/h1-10,24H,11-12H2,(H,25,27)
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n/an/a 5.70E+4n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM50150647
PNG
(CHEMBL3770237)
Show SMILES Clc1ccc(CCNC(=O)Cn2cccc(NCCCc3ccccc3)c2=O)cc1Cl
Show InChI InChI=1S/C24H25Cl2N3O2/c25-20-11-10-19(16-21(20)26)12-14-28-23(30)17-29-15-5-9-22(24(29)31)27-13-4-8-18-6-2-1-3-7-18/h1-3,5-7,9-11,15-16,27H,4,8,12-14,17H2,(H,28,30)
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PubMed
n/an/a 6.80E+4n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM10849
PNG
(1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-d...)
Show SMILES Cn1cnc2n(C)c(=O)n(C)c(=O)c12
Show InChI InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
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Article
PubMed
n/an/a 2.29E+5n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetry


Eur J Med Chem 111: 1-14 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.031
BindingDB Entry DOI: 10.7270/Q2R78H3F
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
* indicates data uncertainty>20%