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PubMed code 26855413

Compile data set for download or QSAR
Found 9 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-glucuronidase


(Bos taurus (Bovine))		BDBM178133
PNG
(3-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...)
Show SMILES Oc1cccc(-c2nc3ncc(Cl)cc3[nH]2)c1O
Show InChI InChI=1S/C12H8ClN3O2/c13-6-4-8-12(14-5-6)16-11(15-8)7-2-1-3-9(17)10(7)18/h1-5,17-18H,(H,14,15,16)
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UniProtKB/TrEMBL

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UniChem

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Article
PubMed
n/an/a 2.93E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM), Puncak Alam Campus



Assay Description
The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o...

Bioorg Chem 65: 48-56 (2016)


Article DOI: 10.1016/j.bioorg.2016.01.007
BindingDB Entry DOI: 10.7270/Q2ZS2V8X
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))		BDBM178131
PNG
(4-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...)
Show SMILES Oc1ccc(cc1O)-c1nc2ncc(Cl)cc2[nH]1
Show InChI InChI=1S/C12H8ClN3O2/c13-7-4-8-12(14-5-7)16-11(15-8)6-1-2-9(17)10(18)3-6/h1-5,17-18H,(H,14,15,16)
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UniProtKB/TrEMBL

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PubMed
n/an/a 3.01E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM), Puncak Alam Campus



Assay Description
The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o...

Bioorg Chem 65: 48-56 (2016)


Article DOI: 10.1016/j.bioorg.2016.01.007
BindingDB Entry DOI: 10.7270/Q2ZS2V8X
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))		BDBM178134
PNG
(2-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...)
Show SMILES Oc1ccc(O)c(c1)-c1nc2ncc(Cl)cc2[nH]1
Show InChI InChI=1S/C12H8ClN3O2/c13-6-3-9-12(14-5-6)16-11(15-9)8-4-7(17)1-2-10(8)18/h1-5,17-18H,(H,14,15,16)
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UniProtKB/TrEMBL

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UniChem

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PubMed
n/an/a 4.61E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM), Puncak Alam Campus



Assay Description
The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o...

Bioorg Chem 65: 48-56 (2016)


Article DOI: 10.1016/j.bioorg.2016.01.007
BindingDB Entry DOI: 10.7270/Q2ZS2V8X
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))		BDBM178139
PNG
(D-Saccharic acid 1,4-lactone)
Show SMILES O[C@@H]([C@H]1OC(=O)C(O)[C@@H]1O)C(O)=O |r|
Show InChI InChI=1S/C6H8O7/c7-1-2(8)6(12)13-4(1)3(9)5(10)11/h1-4,7-9H,(H,10,11)/t1-,2?,3-,4-/m0/s1
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UniProtKB/TrEMBL

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UniChem

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Article
PubMed
n/an/a 4.85E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM), Puncak Alam Campus



Assay Description
The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o...

Bioorg Chem 65: 48-56 (2016)


Article DOI: 10.1016/j.bioorg.2016.01.007
BindingDB Entry DOI: 10.7270/Q2ZS2V8X
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))		BDBM178132
PNG
(4-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...)
Show SMILES Oc1ccc(-c2nc3ncc(Cl)cc3[nH]2)c(O)c1
Show InChI InChI=1S/C12H8ClN3O2/c13-6-3-9-12(14-5-6)16-11(15-9)8-2-1-7(17)4-10(8)18/h1-5,17-18H,(H,14,15,16)
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UniProtKB/TrEMBL

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PubMed
n/an/a 4.96E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM), Puncak Alam Campus



Assay Description
The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o...

Bioorg Chem 65: 48-56 (2016)


Article DOI: 10.1016/j.bioorg.2016.01.007
BindingDB Entry DOI: 10.7270/Q2ZS2V8X
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))		BDBM178138
PNG
(4-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)phenol (...)
Show SMILES Oc1ccc(cc1)-c1nc2ncc(Cl)cc2[nH]1
Show InChI InChI=1S/C12H8ClN3O/c13-8-5-10-12(14-6-8)16-11(15-10)7-1-3-9(17)4-2-7/h1-6,17H,(H,14,15,16)
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UniProtKB/TrEMBL

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PubMed
n/an/a 5.26E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM), Puncak Alam Campus



Assay Description
The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o...

Bioorg Chem 65: 48-56 (2016)


Article DOI: 10.1016/j.bioorg.2016.01.007
BindingDB Entry DOI: 10.7270/Q2ZS2V8X
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))		BDBM178135
PNG
(3-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)phenol (...)
Show SMILES Oc1cccc(c1)-c1nc2ncc(Cl)cc2[nH]1
Show InChI InChI=1S/C12H8ClN3O/c13-8-5-10-12(14-6-8)16-11(15-10)7-2-1-3-9(17)4-7/h1-6,17H,(H,14,15,16)
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UniProtKB/TrEMBL

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PubMed
n/an/a 6.81E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM), Puncak Alam Campus



Assay Description
The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o...

Bioorg Chem 65: 48-56 (2016)


Article DOI: 10.1016/j.bioorg.2016.01.007
BindingDB Entry DOI: 10.7270/Q2ZS2V8X
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))		BDBM178137
PNG
(2-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)-5-metho...)
Show SMILES COc1ccc(-c2nc3ncc(Cl)cc3[nH]2)c(O)c1
Show InChI InChI=1S/C13H10ClN3O2/c1-19-8-2-3-9(11(18)5-8)12-16-10-4-7(14)6-15-13(10)17-12/h2-6,18H,1H3,(H,15,16,17)
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UniProtKB/TrEMBL

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PubMed
n/an/a 1.14E+5n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM), Puncak Alam Campus



Assay Description
The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o...

Bioorg Chem 65: 48-56 (2016)


Article DOI: 10.1016/j.bioorg.2016.01.007
BindingDB Entry DOI: 10.7270/Q2ZS2V8X
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))		BDBM178136
PNG
(2-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)-4-metho...)
Show SMILES COc1ccc(O)c(c1)-c1nc2ncc(Cl)cc2[nH]1
Show InChI InChI=1S/C13H10ClN3O2/c1-19-8-2-3-11(18)9(5-8)12-16-10-4-7(14)6-15-13(10)17-12/h2-6,18H,1H3,(H,15,16,17)
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UniProtKB/TrEMBL

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PubMed
n/an/a 1.29E+5n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM), Puncak Alam Campus



Assay Description
The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o...

Bioorg Chem 65: 48-56 (2016)


Article DOI: 10.1016/j.bioorg.2016.01.007
BindingDB Entry DOI: 10.7270/Q2ZS2V8X
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%