Affinity Data by PubMed id=26860736

PubMed code 26860736

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50150089 (CHEMBL3774723) Show SMILES N=c1sccn1CC(=O)c1cc2ccccc2o1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	10.4	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 10.4 followed by sub...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50241179 ((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...) Show SMILES C1CN2C[C@@H](N=C2S1)c1ccccc1 \|r,c:5\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	7.8	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 7.8 followed by subs...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Alkaline phosphatase, placental type (Homo sapiens (Human))	BDBM50150070 (CHEMBL3774470) Show SMILES C1C(N=C2SC=CN12)c1cc2ccccc2o1 \|c:5,t:2\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	7.8	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of human placental alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 7.8 followed by substr...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Alkaline phosphatase, placental type (Homo sapiens (Human))	BDBM50150089 (CHEMBL3774723) Show SMILES N=c1sccn1CC(=O)c1cc2ccccc2o1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	7.8	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of human placental alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 7.8 followed by substr...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Alkaline phosphatase, placental type (Homo sapiens (Human))	BDBM50150070 (CHEMBL3774470) Show SMILES C1C(N=C2SC=CN12)c1cc2ccccc2o1 \|c:5,t:2\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	10.4	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of human placental alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 10.4 followed by subst...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50150070 (CHEMBL3774470) Show SMILES C1C(N=C2SC=CN12)c1cc2ccccc2o1 \|c:5,t:2\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	10.4	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 10.4 followed by sub...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Alkaline phosphatase, placental type (Homo sapiens (Human))	BDBM50150071 (CHEMBL3774946) Show SMILES OC(Cn1ccsc1=N)c1cc2ccccc2o1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	7.8	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of human placental alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 7.8 followed by substr...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50150070 (CHEMBL3774470) Show SMILES C1C(N=C2SC=CN12)c1cc2ccccc2o1 \|c:5,t:2\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	7.8	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 7.8 followed by subs...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Alkaline phosphatase, placental type (Homo sapiens (Human))	BDBM50241179 ((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...) Show SMILES C1CN2C[C@@H](N=C2S1)c1ccccc1 \|r,c:5\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	7.8	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of human placental alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 7.8 followed by substr...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Alkaline phosphatase, placental type (Homo sapiens (Human))	BDBM50241179 ((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...) Show SMILES C1CN2C[C@@H](N=C2S1)c1ccccc1 \|r,c:5\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	10.4	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of human placental alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 10.4 followed by subst...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50241179 ((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...) Show SMILES C1CN2C[C@@H](N=C2S1)c1ccccc1 \|r,c:5\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	10.4	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 10.4 followed by sub...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50150071 (CHEMBL3774946) Show SMILES OC(Cn1ccsc1=N)c1cc2ccccc2o1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	7.8	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 10.4 followed by sub...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50150089 (CHEMBL3774723) Show SMILES N=c1sccn1CC(=O)c1cc2ccccc2o1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	7.8	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 7.8 followed by subs...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Alkaline phosphatase, placental type (Homo sapiens (Human))	BDBM50150089 (CHEMBL3774723) Show SMILES N=c1sccn1CC(=O)c1cc2ccccc2o1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	10.4	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of human placental alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 10.4 followed by subst...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Alkaline phosphatase, placental type (Homo sapiens (Human))	BDBM50150071 (CHEMBL3774946) Show SMILES OC(Cn1ccsc1=N)c1cc2ccccc2o1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	10.4	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of human placental alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 10.4 followed by subst...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50150071 (CHEMBL3774946) Show SMILES OC(Cn1ccsc1=N)c1cc2ccccc2o1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	7.8	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 7.8 followed by subs...				Bioorg Med Chem Lett 26: 1457-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.061 BindingDB Entry DOI: 10.7270/Q23N2572
Universit£ de Lyon Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%