Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5447 (CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5447 (CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154284 (CHEMBL3775664 | US10106508, Compound II-2) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154289 (CHEMBL3774947) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5446 (CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154288 (CHEMBL3774906) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154259 (CHEMBL3775112) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154260 (CHEMBL3775536) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154256 (CHEMBL3775046) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154255 (CHEMBL3774926 | US10106508, Compound II-1) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 139 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154277 (CHEMBL3774578 | US10106508, Compound II-3) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 163 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154287 (CHEMBL3775459) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 187 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154257 (CHEMBL3774396) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 211 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154290 (CHEMBL3775285) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 245 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154284 (CHEMBL3775664 | US10106508, Compound II-2) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 336 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154282 (CHEMBL3775911) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 354 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154283 (CHEMBL3774471) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 434 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154258 (CHEMBL3775897) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 456 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154261 (CHEMBL3774808) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154279 (CHEMBL3775148) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 519 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154280 (CHEMBL3774712) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 595 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154281 (CHEMBL3774609) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 824 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154285 (CHEMBL3774982) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 829 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154255 (CHEMBL3774926 | US10106508, Compound II-1) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154278 (CHEMBL3775372 | US10106508, Compound II-5) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50154286 (CHEMBL3774910 | US10106508, Compound II-4) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ... | Bioorg Med Chem Lett 26: 1571-5 (2016) Article DOI: 10.1016/j.bmcl.2016.02.009 BindingDB Entry DOI: 10.7270/Q20G3N1W | |||||||||||
More data for this Ligand-Target Pair |