Found 13 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151289
(CHEMBL3771170)Show SMILES [H]C(NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)CC(C)NC(=O)C(N)Cc1cnc[nH]1)(C(C)O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)O)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)CC)C(=O)NC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCNC(N)=N)C(O)=O Show InChI InChI=1S/C150H227N39O46/c1-17-77(10)121(146(231)167-81(14)126(211)175-105(61-87-64-159-92-36-25-24-35-90(87)92)136(221)177-101(56-74(4)5)137(222)186-119(75(6)7)144(229)174-93(37-26-28-52-151)128(213)160-67-113(199)170-99(149(234)235)39-30-54-158-150(155)156)188-138(223)103(58-84-31-20-18-21-32-84)178-133(218)98(47-51-117(205)206)173-132(217)94(38-27-29-53-152)171-125(210)80(13)165-124(209)79(12)166-131(216)97(44-48-110(154)196)169-112(198)66-161-130(215)96(46-50-116(203)204)172-134(219)100(55-73(2)3)176-135(220)102(60-86-40-42-89(195)43-41-86)179-141(226)107(69-190)182-143(228)109(71-192)183-145(230)120(76(8)9)187-140(225)106(63-118(207)208)180-142(227)108(70-191)184-148(233)123(83(16)194)189-139(224)104(59-85-33-22-19-23-34-85)181-147(232)122(82(15)193)185-114(200)68-162-129(214)95(45-49-115(201)202)168-111(197)57-78(11)164-127(212)91(153)62-88-65-157-72-163-88/h18-25,31-36,40-43,64-65,72-83,91,93-109,119-123,159,190-195H,17,26-30,37-39,44-63,66-71,151-153H2,1-16H3,(H2,154,196)(H,157,163)(H,160,213)(H,161,215)(H,162,214)(H,164,212)(H,165,209)(H,166,216)(H,167,231)(H,168,197)(H,169,198)(H,170,199)(H,171,210)(H,172,219)(H,173,217)(H,174,229)(H,175,211)(H,176,220)(H,177,221)(H,178,218)(H,179,226)(H,180,227)(H,181,232)(H,182,228)(H,183,230)(H,184,233)(H,185,200)(H,186,222)(H,187,225)(H,188,223)(H,189,224)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H,234,235)(H4,155,156,158)/t77-,78-,79?,80-,81-,82+,83+,91-,93-,94-,95?,96-,97-,98-,99-,100?,101-,102-,103?,104-,105-,106-,107-,108-,109-,119-,120-,121-,122-,123-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 189 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151290
(CHEMBL3770289)Show SMILES [H]C(NC(=O)CNC(=O)CC(CCC(O)=O)NC(=O)C(C)NC(=O)C(N)Cc1cnc[nH]1)(C(C)O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)O)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)CC)C(=O)NC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCNC(N)=N)C(N)=O Show InChI InChI=1S/C150H228N40O45/c1-17-77(10)121(147(233)168-81(14)128(214)176-105(60-87-64-160-93-36-25-24-35-91(87)93)137(223)178-101(56-74(4)5)138(224)187-119(75(6)7)145(231)175-95(37-26-28-52-151)130(216)162-67-112(199)170-94(124(155)210)39-30-54-159-150(156)157)189-139(225)103(57-84-31-20-18-21-32-84)179-134(220)99(47-51-117(206)207)174-133(219)96(38-27-29-53-152)172-127(213)80(13)165-125(211)78(11)167-132(218)98(45-48-110(154)197)171-113(200)68-163-131(217)97(46-50-116(204)205)173-135(221)100(55-73(2)3)177-136(222)102(59-86-40-43-90(196)44-41-86)180-142(228)107(69-191)183-144(230)109(71-193)184-146(232)120(76(8)9)188-141(227)106(63-118(208)209)181-143(229)108(70-192)185-149(235)123(83(16)195)190-140(226)104(58-85-33-22-19-23-34-85)182-148(234)122(82(15)194)186-114(201)66-161-111(198)62-88(42-49-115(202)203)169-126(212)79(12)166-129(215)92(153)61-89-65-158-72-164-89/h18-25,31-36,40-41,43-44,64-65,72-83,88,92,94-109,119-123,160,191-196H,17,26-30,37-39,42,45-63,66-71,151-153H2,1-16H3,(H2,154,197)(H2,155,210)(H,158,164)(H,161,198)(H,162,216)(H,163,217)(H,165,211)(H,166,215)(H,167,218)(H,168,233)(H,169,212)(H,170,199)(H,171,200)(H,172,213)(H,173,221)(H,174,219)(H,175,231)(H,176,214)(H,177,222)(H,178,223)(H,179,220)(H,180,228)(H,181,229)(H,182,234)(H,183,230)(H,184,232)(H,185,235)(H,186,201)(H,187,224)(H,188,227)(H,189,225)(H,190,226)(H,202,203)(H,204,205)(H,206,207)(H,208,209)(H4,156,157,159)/t77-,78-,79-,80-,81-,82+,83+,88-,92-,94-,95-,96-,97?,98-,99?,100-,101-,102-,103-,104-,105-,106-,107-,108?,109-,119-,120-,121-,122-,123-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151295
(CHEMBL3771156)Show SMILES [H]C(NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)C1(CC1)NC(=O)C(N)Cc1cnc[nH]1)(C(C)O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)O)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)CC)C(=O)NC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCNC(N)=N)C(N)=O Show InChI InChI=1S/C150H226N40O45/c1-16-77(10)119(145(232)167-80(13)125(212)174-104(61-86-64-160-91-35-24-23-34-89(86)91)135(222)176-100(57-74(4)5)136(223)186-117(75(6)7)143(230)173-93(36-25-27-53-151)127(214)161-66-110(198)168-92(122(155)209)38-29-55-159-149(156)157)188-137(224)102(58-83-30-19-17-20-31-83)177-132(219)98(46-50-115(205)206)172-131(218)94(37-26-28-54-152)170-124(211)79(12)165-123(210)78(11)166-130(217)97(43-47-109(154)197)169-111(199)67-162-128(215)95(44-48-113(201)202)171-133(220)99(56-73(2)3)175-134(221)101(60-85-39-41-88(196)42-40-85)178-140(227)106(69-191)181-142(229)108(71-193)182-144(231)118(76(8)9)187-139(226)105(63-116(207)208)179-141(228)107(70-192)183-147(234)121(82(15)195)189-138(225)103(59-84-32-21-18-22-33-84)180-146(233)120(81(14)194)185-112(200)68-163-129(216)96(45-49-114(203)204)184-148(235)150(51-52-150)190-126(213)90(153)62-87-65-158-72-164-87/h17-24,30-35,39-42,64-65,72-82,90,92-108,117-121,160,191-196H,16,25-29,36-38,43-63,66-71,151-153H2,1-15H3,(H2,154,197)(H2,155,209)(H,158,164)(H,161,214)(H,162,215)(H,163,216)(H,165,210)(H,166,217)(H,167,232)(H,168,198)(H,169,199)(H,170,211)(H,171,220)(H,172,218)(H,173,230)(H,174,212)(H,175,221)(H,176,222)(H,177,219)(H,178,227)(H,179,228)(H,180,233)(H,181,229)(H,182,231)(H,183,234)(H,184,235)(H,185,200)(H,186,223)(H,187,226)(H,188,224)(H,189,225)(H,190,213)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,156,157,159)/t77-,78-,79-,80-,81+,82+,90-,92-,93?,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,117-,118-,119-,120-,121-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151286
(CHEMBL3769681)Show SMILES [H]C(NC(=O)CN(C)C(=O)C(CCC(O)=O)NC(=O)C(C)NC(=O)C(N)Cc1cnc[nH]1)(C(C)O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)O)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)CC)C(=O)NC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCNC(N)=N)C(N)=O Show InChI InChI=1S/C150H228N40O45/c1-18-77(10)120(146(232)167-81(14)127(213)175-105(61-87-64-160-92-37-26-25-36-90(87)92)136(222)177-101(57-74(4)5)137(223)186-118(75(6)7)144(230)173-94(38-27-29-53-151)129(215)161-66-111(198)168-93(123(155)209)40-31-55-159-150(156)157)188-138(224)103(58-84-32-21-19-22-33-84)178-133(219)98(47-51-115(203)204)172-132(218)95(39-28-30-54-152)170-125(211)79(12)164-124(210)78(11)166-131(217)97(45-49-110(154)197)169-112(199)67-162-130(216)96(46-50-114(201)202)171-134(220)100(56-73(2)3)176-135(221)102(60-86-41-43-89(196)44-42-86)179-141(227)107(69-191)182-143(229)109(71-193)183-145(231)119(76(8)9)187-140(226)106(63-117(207)208)180-142(228)108(70-192)184-148(234)122(83(16)195)189-139(225)104(59-85-34-23-20-24-35-85)181-147(233)121(82(15)194)185-113(200)68-190(17)149(235)99(48-52-116(205)206)174-126(212)80(13)165-128(214)91(153)62-88-65-158-72-163-88/h19-26,32-37,41-44,64-65,72-83,91,93-109,118-122,160,191-196H,18,27-31,38-40,45-63,66-71,151-153H2,1-17H3,(H2,154,197)(H2,155,209)(H,158,163)(H,161,215)(H,162,216)(H,164,210)(H,165,214)(H,166,217)(H,167,232)(H,168,198)(H,169,199)(H,170,211)(H,171,220)(H,172,218)(H,173,230)(H,174,212)(H,175,213)(H,176,221)(H,177,222)(H,178,219)(H,179,227)(H,180,228)(H,181,233)(H,182,229)(H,183,231)(H,184,234)(H,185,200)(H,186,223)(H,187,226)(H,188,224)(H,189,225)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,156,157,159)/t77-,78-,79-,80-,81-,82-,83+,91-,93-,94-,95-,96-,97?,98-,99-,100-,101-,102-,103-,104?,105-,106-,107-,108-,109-,118-,119-,120-,121-,122?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151294
(CHEMBL3770749)Show SMILES [H][C@](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]1CCC[C@@H]1NC(=O)[C@@H](N)Cc1cnc[nH]1)([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI InChI=1S/C152H230N40O45/c1-16-78(10)122(149(235)169-81(13)128(214)178-107(62-87-65-162-93-37-24-23-35-90(87)93)139(225)180-103(58-75(4)5)140(226)189-120(76(6)7)147(233)177-96(38-25-27-54-153)131(217)163-67-113(200)170-95(125(157)211)41-30-56-161-152(158)159)191-141(227)105(59-84-31-19-17-20-32-84)181-136(222)101(49-53-118(207)208)176-135(221)97(39-26-28-55-154)173-127(213)80(12)167-126(212)79(11)168-134(220)100(46-50-112(156)199)171-114(201)68-164-133(219)99(48-52-117(205)206)175-137(223)102(57-74(2)3)179-138(224)104(61-86-42-44-89(198)45-43-86)182-144(230)109(70-193)185-146(232)111(72-195)186-148(234)121(77(8)9)190-143(229)108(64-119(209)210)183-145(231)110(71-194)187-151(237)124(83(15)197)192-142(228)106(60-85-33-21-18-22-34-85)184-150(236)123(82(14)196)188-115(202)69-165-132(218)98(47-51-116(203)204)174-129(215)91-36-29-40-94(91)172-130(216)92(155)63-88-66-160-73-166-88/h17-24,31-35,37,42-45,65-66,73-83,91-92,94-111,120-124,162,193-198H,16,25-30,36,38-41,46-64,67-72,153-155H2,1-15H3,(H2,156,199)(H2,157,211)(H,160,166)(H,163,217)(H,164,219)(H,165,218)(H,167,212)(H,168,220)(H,169,235)(H,170,200)(H,171,201)(H,172,216)(H,173,213)(H,174,215)(H,175,223)(H,176,221)(H,177,233)(H,178,214)(H,179,224)(H,180,225)(H,181,222)(H,182,230)(H,183,231)(H,184,236)(H,185,232)(H,186,234)(H,187,237)(H,188,202)(H,189,226)(H,190,229)(H,191,227)(H,192,228)(H,203,204)(H,205,206)(H,207,208)(H,209,210)(H4,158,159,161)/t78-,79-,80-,81-,82+,83+,91-,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-,124-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0770 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151287
(CHEMBL3769422)Show SMILES [H]C(NC(=O)C(Cc1ccccc1)NC(=O)C([H])(C(C)O)N(C)C(=O)CNC(=O)C(CCC(O)=O)NC(=O)C(C)NC(=O)C(N)Cc1cnc[nH]1)(C(C)O)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)CC)C(=O)NC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCNC(N)=N)C(N)=O Show InChI InChI=1S/C150H228N40O45/c1-18-77(10)120(147(233)168-81(14)127(213)176-105(61-87-64-160-92-37-26-25-36-90(87)92)137(223)178-101(57-74(4)5)138(224)186-118(75(6)7)145(231)175-94(38-27-29-53-151)129(215)161-66-111(198)169-93(123(155)209)40-31-55-159-150(156)157)188-139(225)103(58-84-32-21-19-22-33-84)179-134(220)99(48-52-116(205)206)174-133(219)95(39-28-30-54-152)171-125(211)79(12)165-124(210)78(11)167-132(218)98(45-49-110(154)197)170-112(199)67-162-130(216)97(47-51-115(203)204)173-135(221)100(56-73(2)3)177-136(222)102(60-86-41-43-89(196)44-42-86)180-142(228)107(69-191)183-144(230)109(71-193)184-146(232)119(76(8)9)187-141(227)106(63-117(207)208)181-143(229)108(70-192)185-148(234)121(82(15)194)189-140(226)104(59-85-34-23-20-24-35-85)182-149(235)122(83(16)195)190(17)113(200)68-163-131(217)96(46-50-114(201)202)172-126(212)80(13)166-128(214)91(153)62-88-65-158-72-164-88/h19-26,32-37,41-44,64-65,72-83,91,93-109,118-122,160,191-196H,18,27-31,38-40,45-63,66-71,151-153H2,1-17H3,(H2,154,197)(H2,155,209)(H,158,164)(H,161,215)(H,162,216)(H,163,217)(H,165,210)(H,166,214)(H,167,218)(H,168,233)(H,169,198)(H,170,199)(H,171,211)(H,172,212)(H,173,221)(H,174,219)(H,175,231)(H,176,213)(H,177,222)(H,178,223)(H,179,220)(H,180,228)(H,181,229)(H,182,235)(H,183,230)(H,184,232)(H,185,234)(H,186,224)(H,187,227)(H,188,225)(H,189,226)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,156,157,159)/t77-,78-,79-,80-,81-,82+,83-,91-,93-,94-,95-,96-,97-,98?,99-,100-,101-,102-,103-,104?,105-,106-,107-,108-,109-,118-,119-,120-,121?,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151296
(CHEMBL3769427)Show SMILES [H]C(NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)C(C)NC(=O)C(N)Cc1cnc[nH]1)(C(C)O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)O)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)CC)C(=O)NC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCNC(N)=N)C(N)=O Show InChI InChI=1S/C149H226N40O45/c1-17-76(10)119(146(232)167-80(14)126(212)175-104(60-86-63-159-91-36-25-24-35-89(86)91)136(222)177-100(56-73(4)5)137(223)186-117(74(6)7)144(230)174-93(37-26-28-52-150)128(214)160-65-110(197)168-92(122(154)208)39-30-54-158-149(155)156)188-138(224)102(57-83-31-20-18-21-32-83)178-133(219)98(47-51-115(204)205)173-132(218)94(38-27-29-53-151)170-124(210)78(12)164-123(209)77(11)166-131(217)97(44-48-109(153)196)169-111(198)66-161-130(216)96(46-50-114(202)203)172-134(220)99(55-72(2)3)176-135(221)101(59-85-40-42-88(195)43-41-85)179-141(227)106(68-190)182-143(229)108(70-192)183-145(231)118(75(8)9)187-140(226)105(62-116(206)207)180-142(228)107(69-191)184-148(234)121(82(16)194)189-139(225)103(58-84-33-22-19-23-34-84)181-147(233)120(81(15)193)185-112(199)67-162-129(215)95(45-49-113(200)201)171-125(211)79(13)165-127(213)90(152)61-87-64-157-71-163-87/h18-25,31-36,40-43,63-64,71-82,90,92-108,117-121,159,190-195H,17,26-30,37-39,44-62,65-70,150-152H2,1-16H3,(H2,153,196)(H2,154,208)(H,157,163)(H,160,214)(H,161,216)(H,162,215)(H,164,209)(H,165,213)(H,166,217)(H,167,232)(H,168,197)(H,169,198)(H,170,210)(H,171,211)(H,172,220)(H,173,218)(H,174,230)(H,175,212)(H,176,221)(H,177,222)(H,178,219)(H,179,227)(H,180,228)(H,181,233)(H,182,229)(H,183,231)(H,184,234)(H,185,199)(H,186,223)(H,187,226)(H,188,224)(H,189,225)(H,200,201)(H,202,203)(H,204,205)(H,206,207)(H4,155,156,158)/t76-,77-,78-,79-,80-,81-,82+,90-,92-,93-,94-,95-,96-,97?,98-,99-,100-,101-,102-,103?,104-,105-,106-,107-,108-,117-,118-,119-,120-,121?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151291
(CHEMBL3769858)Show SMILES [H][C@](NC(=O)CCNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI InChI=1S/C150H228N40O45/c1-17-77(10)120(147(233)168-81(14)127(213)176-105(62-87-65-161-92-36-25-24-35-90(87)92)137(223)178-101(58-74(4)5)138(224)187-118(75(6)7)145(231)175-94(37-26-28-53-151)130(216)162-67-112(199)169-93(123(155)209)39-30-55-160-150(156)157)189-139(225)103(59-84-31-20-18-21-32-84)179-134(220)99(47-51-116(205)206)174-133(219)95(38-27-29-54-152)171-125(211)79(12)165-124(210)78(11)167-132(218)98(44-48-110(154)197)170-113(200)68-163-131(217)97(46-50-115(203)204)173-135(221)100(57-73(2)3)177-136(222)102(61-86-40-42-89(196)43-41-86)180-142(228)107(69-191)183-144(230)109(71-193)184-146(232)119(76(8)9)188-141(227)106(64-117(207)208)181-143(229)108(70-192)185-149(235)122(83(16)195)190-140(226)104(60-85-33-22-19-23-34-85)182-148(234)121(82(15)194)186-111(198)52-56-159-129(215)96(45-49-114(201)202)172-126(212)80(13)166-128(214)91(153)63-88-66-158-72-164-88/h18-25,31-36,40-43,65-66,72-83,91,93-109,118-122,161,191-196H,17,26-30,37-39,44-64,67-71,151-153H2,1-16H3,(H2,154,197)(H2,155,209)(H,158,164)(H,159,215)(H,162,216)(H,163,217)(H,165,210)(H,166,214)(H,167,218)(H,168,233)(H,169,199)(H,170,200)(H,171,211)(H,172,212)(H,173,221)(H,174,219)(H,175,231)(H,176,213)(H,177,222)(H,178,223)(H,179,220)(H,180,228)(H,181,229)(H,182,234)(H,183,230)(H,184,232)(H,185,235)(H,186,198)(H,187,224)(H,188,227)(H,189,225)(H,190,226)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,156,157,160)/t77-,78-,79-,80-,81-,82+,83+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,118-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0640 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151284
(CHEMBL3770379)Show SMILES [H]C(NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)C(C)N(C)C(=O)C(N)Cc1cnc[nH]1)(C(C)O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)O)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)CC)C(=O)NC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCNC(N)=N)C(N)=O Show InChI InChI=1S/C150H228N40O45/c1-18-77(10)120(146(232)167-80(13)126(212)175-105(61-87-64-160-92-37-26-25-36-90(87)92)136(222)177-101(57-74(4)5)137(223)186-118(75(6)7)144(230)174-94(38-27-29-53-151)128(214)161-66-111(198)168-93(123(155)209)40-31-55-159-150(156)157)188-138(224)103(58-84-32-21-19-22-33-84)178-133(219)99(48-52-116(205)206)173-132(218)95(39-28-30-54-152)170-125(211)79(12)165-124(210)78(11)166-131(217)98(45-49-110(154)197)169-112(199)67-162-130(216)97(47-51-115(203)204)172-134(220)100(56-73(2)3)176-135(221)102(60-86-41-43-89(196)44-42-86)179-141(227)107(69-191)182-143(229)109(71-193)183-145(231)119(76(8)9)187-140(226)106(63-117(207)208)180-142(228)108(70-192)184-148(234)122(83(16)195)189-139(225)104(59-85-34-23-20-24-35-85)181-147(233)121(82(15)194)185-113(200)68-163-129(215)96(46-50-114(201)202)171-127(213)81(14)190(17)149(235)91(153)62-88-65-158-72-164-88/h19-26,32-37,41-44,64-65,72-83,91,93-109,118-122,160,191-196H,18,27-31,38-40,45-63,66-71,151-153H2,1-17H3,(H2,154,197)(H2,155,209)(H,158,164)(H,161,214)(H,162,216)(H,163,215)(H,165,210)(H,166,217)(H,167,232)(H,168,198)(H,169,199)(H,170,211)(H,171,213)(H,172,220)(H,173,218)(H,174,230)(H,175,212)(H,176,221)(H,177,222)(H,178,219)(H,179,227)(H,180,228)(H,181,233)(H,182,229)(H,183,231)(H,184,234)(H,185,200)(H,186,223)(H,187,226)(H,188,224)(H,189,225)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,156,157,159)/t77-,78-,79-,80-,81-,82-,83+,91-,93-,94-,95-,96-,97-,98?,99-,100-,101-,102-,103-,104?,105-,106-,107-,108-,109-,118-,119-,120-,121-,122?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151288
(CHEMBL3770835)Show SMILES [H]C(NC(=O)C(Cc1ccccc1)N(C)C(=O)C([H])(NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)C(C)NC(=O)C(N)Cc1cnc[nH]1)C(C)O)(C(C)O)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)CC)C(=O)NC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCNC(N)=N)C(O)=O Show InChI InChI=1S/C150H227N39O46/c1-18-77(10)120(146(231)167-81(14)126(211)175-104(61-87-64-159-92-37-26-25-36-90(87)92)136(221)177-101(57-74(4)5)137(222)185-118(75(6)7)144(229)174-93(38-27-29-53-151)128(213)160-67-112(198)169-99(149(234)235)40-31-55-158-150(155)156)187-138(223)103(58-84-32-21-19-22-33-84)178-133(218)98(48-52-116(204)205)173-132(217)94(39-28-30-54-152)170-124(209)79(12)164-123(208)78(11)166-131(216)97(45-49-110(154)196)168-111(197)66-161-130(215)96(47-51-115(202)203)172-134(219)100(56-73(2)3)176-135(220)102(59-86-41-43-89(195)44-42-86)179-140(225)106(69-190)181-142(227)108(71-192)182-145(230)119(76(8)9)186-139(224)105(63-117(206)207)180-141(226)107(70-191)183-147(232)121(82(15)193)188-143(228)109(60-85-34-23-20-24-35-85)189(17)148(233)122(83(16)194)184-113(199)68-162-129(214)95(46-50-114(200)201)171-125(210)80(13)165-127(212)91(153)62-88-65-157-72-163-88/h19-26,32-37,41-44,64-65,72-83,91,93-109,118-122,159,190-195H,18,27-31,38-40,45-63,66-71,151-153H2,1-17H3,(H2,154,196)(H,157,163)(H,160,213)(H,161,215)(H,162,214)(H,164,208)(H,165,212)(H,166,216)(H,167,231)(H,168,197)(H,169,198)(H,170,209)(H,171,210)(H,172,219)(H,173,217)(H,174,229)(H,175,211)(H,176,220)(H,177,221)(H,178,218)(H,179,225)(H,180,226)(H,181,227)(H,182,230)(H,183,232)(H,184,199)(H,185,222)(H,186,224)(H,187,223)(H,188,228)(H,200,201)(H,202,203)(H,204,205)(H,206,207)(H,234,235)(H4,155,156,158)/t77-,78-,79-,80-,81-,82+,83-,91-,93-,94-,95-,96-,97?,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109?,118-,119-,120-,121?,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151285
(CHEMBL3771064)Show SMILES [H]C(NC(=O)CNC(=O)C(CCC(O)=O)N(C)C(=O)C(C)NC(=O)C(N)Cc1cnc[nH]1)(C(C)O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)O)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)CC)C(=O)NC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCNC(N)=N)C(N)=O Show InChI InChI=1S/C150H228N40O45/c1-18-77(10)120(146(232)167-80(13)126(212)175-104(61-87-64-160-92-37-26-25-36-90(87)92)135(221)177-100(57-74(4)5)136(222)186-118(75(6)7)144(230)174-94(38-27-29-53-151)128(214)161-66-111(198)169-93(123(155)209)40-31-55-159-150(156)157)188-137(223)102(58-84-32-21-19-22-33-84)178-132(218)98(47-51-115(203)204)173-131(217)95(39-28-30-54-152)171-125(211)79(12)165-124(210)78(11)166-130(216)97(45-49-110(154)197)170-112(199)67-162-129(215)96(46-50-114(201)202)172-133(219)99(56-73(2)3)176-134(220)101(60-86-41-43-89(196)44-42-86)179-140(226)106(69-191)182-142(228)108(71-193)183-145(231)119(76(8)9)187-139(225)105(63-117(207)208)180-141(227)107(70-192)184-148(234)122(83(16)195)189-138(224)103(59-85-34-23-20-24-35-85)181-147(233)121(82(15)194)185-113(200)68-163-143(229)109(48-52-116(205)206)190(17)149(235)81(14)168-127(213)91(153)62-88-65-158-72-164-88/h19-26,32-37,41-44,64-65,72-83,91,93-109,118-122,160,191-196H,18,27-31,38-40,45-63,66-71,151-153H2,1-17H3,(H2,154,197)(H2,155,209)(H,158,164)(H,161,214)(H,162,215)(H,163,229)(H,165,210)(H,166,216)(H,167,232)(H,168,213)(H,169,198)(H,170,199)(H,171,211)(H,172,219)(H,173,217)(H,174,230)(H,175,212)(H,176,220)(H,177,221)(H,178,218)(H,179,226)(H,180,227)(H,181,233)(H,182,228)(H,183,231)(H,184,234)(H,185,200)(H,186,222)(H,187,225)(H,188,223)(H,189,224)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,156,157,159)/t77-,78-,79-,80-,81-,82-,83+,91-,93-,94-,95-,96-,97?,98-,99-,100-,101-,102-,103?,104-,105-,106-,107-,108-,109-,118-,119-,120-,121-,122?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151293
(CHEMBL3769440)Show SMILES [H]C(NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)C(C)CNC(=O)C(N)Cc1cnc[nH]1)(C(C)O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)O)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC([H])(C(C)CC)C(=O)NC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCNC(N)=N)C(N)=O Show InChI InChI=1S/C150H228N40O45/c1-17-77(10)120(147(233)168-81(14)127(213)176-105(60-87-64-160-92-36-25-24-35-90(87)92)137(223)178-101(56-74(4)5)138(224)187-118(75(6)7)145(231)175-94(37-26-28-52-151)129(215)162-66-111(198)169-93(123(155)209)39-30-54-159-150(156)157)189-139(225)103(57-84-31-20-18-21-32-84)179-134(220)99(47-51-116(205)206)174-133(219)95(38-27-29-53-152)172-126(212)80(13)166-125(211)79(12)167-132(218)98(44-48-110(154)197)170-112(199)67-163-131(217)97(46-50-115(203)204)173-135(221)100(55-73(2)3)177-136(222)102(59-86-40-42-89(196)43-41-86)180-142(228)107(69-191)183-144(230)109(71-193)184-146(232)119(76(8)9)188-141(227)106(62-117(207)208)181-143(229)108(70-192)185-149(235)122(83(16)195)190-140(226)104(58-85-33-22-19-23-34-85)182-148(234)121(82(15)194)186-113(200)68-164-130(216)96(45-49-114(201)202)171-124(210)78(11)63-161-128(214)91(153)61-88-65-158-72-165-88/h18-25,31-36,40-43,64-65,72-83,91,93-109,118-122,160,191-196H,17,26-30,37-39,44-63,66-71,151-153H2,1-16H3,(H2,154,197)(H2,155,209)(H,158,165)(H,161,214)(H,162,215)(H,163,217)(H,164,216)(H,166,211)(H,167,218)(H,168,233)(H,169,198)(H,170,199)(H,171,210)(H,172,212)(H,173,221)(H,174,219)(H,175,231)(H,176,213)(H,177,222)(H,178,223)(H,179,220)(H,180,228)(H,181,229)(H,182,234)(H,183,230)(H,184,232)(H,185,235)(H,186,200)(H,187,224)(H,188,227)(H,189,225)(H,190,226)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,156,157,159)/t77-,78-,79-,80-,81-,82+,83+,91-,93-,94-,95-,96-,97-,98?,99-,100?,101-,102-,103-,104-,105-,106-,107-,108-,109-,118?,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50151292
(CHEMBL3770062)Show SMILES [H][C@](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CCNC(=O)[C@@H](N)Cc1cnc[nH]1)([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI InChI=1S/C149H226N40O45/c1-16-77(10)120(146(232)167-80(13)126(212)175-104(61-86-64-160-91-35-24-23-34-89(86)91)136(222)177-100(57-74(4)5)137(223)186-118(75(6)7)144(230)174-93(36-25-27-52-150)128(214)161-66-111(198)168-92(123(154)209)38-29-54-159-149(155)156)188-138(224)102(58-83-30-19-17-20-31-83)178-133(219)98(46-50-116(205)206)173-132(218)94(37-26-28-53-151)171-125(211)79(12)165-124(210)78(11)166-131(217)97(43-47-109(153)196)170-112(199)67-162-130(216)96(45-49-115(203)204)172-134(220)99(56-73(2)3)176-135(221)101(60-85-39-41-88(195)42-40-85)179-141(227)106(69-190)182-143(229)108(71-192)183-145(231)119(76(8)9)187-140(226)105(63-117(207)208)180-142(228)107(70-191)184-148(234)122(82(15)194)189-139(225)103(59-84-32-21-18-22-33-84)181-147(233)121(81(14)193)185-113(200)68-163-129(215)95(44-48-114(201)202)169-110(197)51-55-158-127(213)90(152)62-87-65-157-72-164-87/h17-24,30-35,39-42,64-65,72-82,90,92-108,118-122,160,190-195H,16,25-29,36-38,43-63,66-71,150-152H2,1-15H3,(H2,153,196)(H2,154,209)(H,157,164)(H,158,213)(H,161,214)(H,162,216)(H,163,215)(H,165,210)(H,166,217)(H,167,232)(H,168,198)(H,169,197)(H,170,199)(H,171,211)(H,172,220)(H,173,218)(H,174,230)(H,175,212)(H,176,221)(H,177,222)(H,178,219)(H,179,227)(H,180,228)(H,181,233)(H,182,229)(H,183,231)(H,184,234)(H,185,200)(H,186,223)(H,187,226)(H,188,224)(H,189,225)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,155,156,159)/t77-,78-,79-,80-,81+,82+,90-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,118-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0330 | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Activation of human GLP1R expressed in HEK293 cells preincubated for 30 mins followed by addition of cAMP-d2 conjugate/cryptate conjugate incubated f... |
Bioorg Med Chem 24: 1163-70 (2016)
Article DOI: 10.1016/j.bmc.2016.01.036
BindingDB Entry DOI: 10.7270/Q2V126PX |
More data for this
Ligand-Target Pair | |
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