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PubMed code 26922232

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154763
PNG
(CHEMBL3774415)
Show SMILES COc1ccc(c(Cc2c(C)n(CC(O)=O)c3CCCC(=O)c23)c1)S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C25H24FNO6S/c1-15-20(25-21(4-3-5-22(25)28)27(15)14-24(29)30)13-16-12-18(33-2)8-11-23(16)34(31,32)19-9-6-17(26)7-10-19/h6-12H,3-5,13-14H2,1-2H3,(H,29,30)
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n/an/a 2n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154805
PNG
(CHEMBL3775213)
Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c2c(CCCC2=O)n1CC(O)=O
Show InChI InChI=1S/C24H22FNO5S/c1-15-19(24-20(6-4-7-21(24)27)26(15)14-23(28)29)13-16-5-2-3-8-22(16)32(30,31)18-11-9-17(25)10-12-18/h2-3,5,8-12H,4,6-7,13-14H2,1H3,(H,28,29)
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n/an/a 2n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154762
PNG
(CHEMBL3774971)
Show SMILES COc1ccc(c(Cn2c(C)c(CC(O)=O)c3ccc(C)nc23)c1)S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C25H23FN2O5S/c1-15-4-10-21-22(13-24(29)30)16(2)28(25(21)27-15)14-17-12-19(33-3)7-11-23(17)34(31,32)20-8-5-18(26)6-9-20/h4-12H,13-14H2,1-3H3,(H,29,30)
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n/an/a 4n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154760
PNG
(CHEMBL3774449)
Show SMILES COc1ccc(c(Cc2c(C)c(CC(O)=O)c3ccncn23)c1)S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C24H21FN2O5S/c1-15-20(13-24(28)29)21-9-10-26-14-27(21)22(15)12-16-11-18(32-2)5-8-23(16)33(30,31)19-6-3-17(25)4-7-19/h3-11,14H,12-13H2,1-2H3,(H,28,29)
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n/an/a 5n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50034809
PNG
(CHEMBL3338090)
Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(CCNC2=O)n1CC(O)=O
Show InChI InChI=1S/C23H22N2O5S/c1-15-18(22-19(11-12-24-23(22)28)25(15)14-21(26)27)13-16-7-5-6-10-20(16)31(29,30)17-8-3-2-4-9-17/h2-10H,11-14H2,1H3,(H,24,28)(H,26,27)
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n/an/a 5n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154760
PNG
(CHEMBL3774449)
Show SMILES COc1ccc(c(Cc2c(C)c(CC(O)=O)c3ccncn23)c1)S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C24H21FN2O5S/c1-15-20(13-24(28)29)21-9-10-26-14-27(21)22(15)12-16-11-18(32-2)5-8-23(16)33(30,31)19-6-3-17(25)4-7-19/h3-11,14H,12-13H2,1-2H3,(H,28,29)
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n/an/a 6n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTH2 receptor in human eosinophils by ESC assay

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50434456
PNG
(CHEMBL2387692)
Show SMILES Cc1c(CC(O)=O)c(nn1Cc1ccccc1S(=O)(=O)c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C25H22N2O4S/c1-18-22(16-24(28)29)25(19-10-4-2-5-11-19)26-27(18)17-20-12-8-9-15-23(20)32(30,31)21-13-6-3-7-14-21/h2-15H,16-17H2,1H3,(H,28,29)
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n/an/a 7n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154809
PNG
(CHEMBL3775081)
Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)nc(-c2ccccc2)n1CC(O)=O
Show InChI InChI=1S/C25H21FN2O4S/c1-17-22(27-25(28(17)16-24(29)30)18-7-3-2-4-8-18)15-19-9-5-6-10-23(19)33(31,32)21-13-11-20(26)12-14-21/h2-14H,15-16H2,1H3,(H,29,30)
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n/an/a 8n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154639
PNG
(CHEMBL3774535)
Show SMILES Cc1c(CC(O)=O)c2ccncn2c1Cc1ccccc1S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C23H20N2O4S/c1-16-19(14-23(26)27)20-11-12-24-15-25(20)21(16)13-17-7-5-6-10-22(17)30(28,29)18-8-3-2-4-9-18/h2-12,15H,13-14H2,1H3,(H,26,27)
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n/an/a 12n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTH2 receptor in human eosinophils by ESC assay

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50434451
PNG
(CHEMBL2385124)
Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(O)=O
Show InChI InChI=1S/C24H20FNO4S/c1-16-20(21-14-18(25)11-12-22(21)26(16)15-24(27)28)13-17-7-5-6-10-23(17)31(29,30)19-8-3-2-4-9-19/h2-12,14H,13,15H2,1H3,(H,27,28)
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n/an/a 14n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154764
PNG
(CHEMBL3774547)
Show SMILES Cc1c(CC(O)=O)c2ccc(C)nc2n1Cc1ccccc1S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C24H22N2O4S/c1-16-12-13-20-21(14-23(27)28)17(2)26(24(20)25-16)15-18-8-6-7-11-22(18)31(29,30)19-9-4-3-5-10-19/h3-13H,14-15H2,1-2H3,(H,27,28)
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n/an/a 14n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154761
PNG
(CHEMBL3775880)
Show SMILES COc1ccc(c(Cn2cc(CC(O)=O)c3ccc(C)nc23)c1)S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C24H21FN2O5S/c1-15-3-9-21-16(12-23(28)29)13-27(24(21)26-15)14-17-11-19(32-2)6-10-22(17)33(30,31)20-7-4-18(25)5-8-20/h3-11,13H,12,14H2,1-2H3,(H,28,29)
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n/an/a 18n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154639
PNG
(CHEMBL3774535)
Show SMILES Cc1c(CC(O)=O)c2ccncn2c1Cc1ccccc1S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C23H20N2O4S/c1-16-19(14-23(26)27)20-11-12-24-15-25(20)21(16)13-17-7-5-6-10-22(17)30(28,29)18-8-3-2-4-9-18/h2-12,15H,13-14H2,1H3,(H,26,27)
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n/an/a 28n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154765
PNG
(CHEMBL3774567)
Show SMILES OC(=O)Cc1cc(Cc2ccccc2S(=O)(=O)c2ccccc2)c2nc(ccn12)C(F)(F)F
Show InChI InChI=1S/C23H17F3N2O4S/c24-23(25,26)20-10-11-28-17(14-21(29)30)13-16(22(28)27-20)12-15-6-4-5-9-19(15)33(31,32)18-7-2-1-3-8-18/h1-11,13H,12,14H2,(H,29,30)
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n/an/a 47n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154784
PNG
(CHEMBL3775706)
Show SMILES OC(=O)Cc1nn(Cc2ccccc2S(=O)(=O)c2ccccc2)c(=O)c2ccccc12
Show InChI InChI=1S/C23H18N2O5S/c26-22(27)14-20-18-11-5-6-12-19(18)23(28)25(24-20)15-16-8-4-7-13-21(16)31(29,30)17-9-2-1-3-10-17/h1-13H,14-15H2,(H,26,27)
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n/an/a 65n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50444782
PNG
(CHEMBL3099133)
Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c(nn1CC(O)=O)-c1ccccc1
Show InChI InChI=1S/C25H22N2O4S/c1-18-22(25(19-10-4-2-5-11-19)26-27(18)17-24(28)29)16-20-12-8-9-15-23(20)32(30,31)21-13-6-3-7-14-21/h2-15H,16-17H2,1H3,(H,28,29)
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n/an/a 85n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154806
PNG
(CHEMBL3775546)
Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c2CCCCc2n1CC(O)=O
Show InChI InChI=1S/C24H24FNO4S/c1-16-21(20-7-3-4-8-22(20)26(16)15-24(27)28)14-17-6-2-5-9-23(17)31(29,30)19-12-10-18(25)11-13-19/h2,5-6,9-13H,3-4,7-8,14-15H2,1H3,(H,27,28)
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n/an/a 104n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154807
PNG
(CHEMBL3774574)
Show SMILES OC(=O)Cc1cc(Cl)c(=O)n(Cc2ccccc2S(=O)(=O)c2ccccc2)c1
Show InChI InChI=1S/C20H16ClNO5S/c21-17-10-14(11-19(23)24)12-22(20(17)25)13-15-6-4-5-9-18(15)28(26,27)16-7-2-1-3-8-16/h1-10,12H,11,13H2,(H,23,24)
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n/an/a 860n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154812
PNG
(CHEMBL3775461)
Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1CC(O)=O
Show InChI InChI=1S/C25H22N2O5S/c1-18-22(25(30)27(26(18)17-24(28)29)20-11-4-2-5-12-20)16-19-10-8-9-15-23(19)33(31,32)21-13-6-3-7-14-21/h2-15H,16-17H2,1H3,(H,28,29)
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n/an/a 970n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154776
PNG
(CHEMBL3774629)
Show SMILES OC(=O)CN1c2cccnc2N(Cc2ccccc2S(=O)(=O)c2ccccc2)S1(=O)=O
Show InChI InChI=1S/C20H17N3O6S2/c24-19(25)14-22-17-10-6-12-21-20(17)23(31(22,28)29)13-15-7-4-5-11-18(15)30(26,27)16-8-2-1-3-9-16/h1-12H,13-14H2,(H,24,25)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154810
PNG
(CHEMBL3775125)
Show SMILES OC(=O)Cn1c(nn(Cc2ccccc2S(=O)(=O)c2ccccc2)c1=O)-c1ccccc1
Show InChI InChI=1S/C23H19N3O5S/c27-21(28)16-25-22(17-9-3-1-4-10-17)24-26(23(25)29)15-18-11-7-8-14-20(18)32(30,31)19-12-5-2-6-13-19/h1-14H,15-16H2,(H,27,28)
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n/an/a 2.40E+3n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154766
PNG
(CHEMBL3775763)
Show SMILES OC(=O)Cc1nc(Cc2ccccc2S(=O)(=O)c2ccccc2)n2ccccc12
Show InChI InChI=1S/C22H18N2O4S/c25-22(26)15-18-19-11-6-7-13-24(19)21(23-18)14-16-8-4-5-12-20(16)29(27,28)17-9-2-1-3-10-17/h1-13H,14-15H2,(H,25,26)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154811
PNG
(CHEMBL3775455)
Show SMILES Cc1c(-c2ccccc2)n(CC(O)=O)c(=O)n1Cc1ccccc1S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C25H21FN2O5S/c1-17-24(18-7-3-2-4-8-18)28(16-23(29)30)25(31)27(17)15-19-9-5-6-10-22(19)34(32,33)21-13-11-20(26)12-14-21/h2-14H,15-16H2,1H3,(H,29,30)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50154808
PNG
(CHEMBL3774722)
Show SMILES OC(=O)Cc1ccc(=O)n(Cc2ccccc2S(=O)(=O)c2ccccc2)c1
Show InChI InChI=1S/C20H17NO5S/c22-19-11-10-15(12-20(23)24)13-21(19)14-16-6-4-5-9-18(16)27(25,26)17-7-2-1-3-8-17/h1-11,13H,12,14H2,(H,23,24)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter

Eur J Med Chem 113: 102-33 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.023
BindingDB Entry DOI: 10.7270/Q2K64KXM
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%