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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | UniProtKB/SwissProt GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 157 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179793 (1-(2-Fluorobenzyl)-4-(((6-methoxycoumarin-7-yl)oxy...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 215 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179796 (1-(2,3-Difluorobenzyl)-4-(((6-methoxycoumarin-7-yl...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179790 (1-(2-Chlorobenzyl)-4-(((6-methoxycoumarin-7-yl)oxy...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179791 (1-(3-Chlorobenzyl)-4-(((6-methoxycoumarin-7-yl)oxy...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 397 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179797 (1-(2,6-Difluorobenzyl)-4-(((6-methoxycoumarin-7-yl...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179794 (1-(3-Fluorobenzyl)-4-(((6-methoxycoumarin-7-yl)oxy...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 684 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179788 (1-(3-Phenylpropyl)-4-(((6-methoxycoumarin-7-yl)oxy...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179795 (1-(4-Fluorobenzyl)-4-(((6-methoxycoumarin-7-yl)oxy...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179786 (1-Benzyl-4-(((6-methoxycoumarin-7-yl)oxy)methyl)py...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179789 (1-(Naphthalen-2ylmethyl)-4-(((6-methoxycoumarin-7-...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.28E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179787 (1-Phenylethyl-4-(((6-methoxycoumarin-7-yl)oxy)meth...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.05E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179792 (1-(4-Chlorobenzyl)-4-(((6-methoxycoumarin-7-yl)oxy...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.07E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179784 (1-Propyl-4-(((6-methoxycoumarin-7-yl)oxy)methyl)py...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM179785 (1-Butyl-4-(((6-methoxycoumarin-7-yl)oxy)methyl)pyr...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.57E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Chulabhorn Research Institute | Assay Description AChE inhibitory activity was measured with a Molecular Devices Spectra Max Plus 384 spectrophotometer (CA, USA) based on Ellman's method with sli... | Bioorg Chem 65: 137-45 (2016) Article DOI: 10.1016/j.bioorg.2015.12.002 BindingDB Entry DOI: 10.7270/Q20K27BM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
