BindingDB logo
myBDB logout

PubMed code 26944616

Compile data set for download or QSAR
Found 6 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50152687
PNG
(CHEMBL3781078)
Show SMILES [H][C@]12[C@H](O)[C@H](O)CN1C(=O)CN1C(=O)c3ccccc3S[C@]21[H] |r|
Show InChI InChI=1S/C14H14N2O4S/c17-8-5-15-10(18)6-16-13(20)7-3-1-2-4-9(7)21-14(16)11(15)12(8)19/h1-4,8,11-12,14,17,19H,5-6H2/t8-,11-,12-,14-/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 820n/an/an/an/an/an/a



Hebei University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase using DIG-labeled dNTPs as substrate after 1 hr by ELISA


Bioorg Med Chem Lett 26: 1738-41 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.049
BindingDB Entry DOI: 10.7270/Q2Q52RHF
More data for this
Ligand-Target Pair
Reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50152688
PNG
(CHEMBL3780390)
Show SMILES [H][C@]12[C@H](O)[C@H](O)CN1C(=O)[C@@H](C)N1C(=O)c3ccccc3S[C@@]21[H] |r|
Show InChI InChI=1S/C15H16N2O4S/c1-7-13(20)16-6-9(18)12(19)11(16)15-17(7)14(21)8-4-2-3-5-10(8)22-15/h2-5,7,9,11-12,15,18-19H,6H2,1H3/t7-,9-,11-,12-,15+/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.01E+3n/an/an/an/an/an/a



Hebei University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase using DIG-labeled dNTPs as substrate after 1 hr by ELISA


Bioorg Med Chem Lett 26: 1738-41 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.049
BindingDB Entry DOI: 10.7270/Q2Q52RHF
More data for this
Ligand-Target Pair
Reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50152686
PNG
(CHEMBL3781141)
Show SMILES [H][C@]12[C@H](O)[C@H](O)CN1C(=O)[C@H](C)N1C(=O)c3ccccc3S[C@]21[H] |r|
Show InChI InChI=1S/C15H16N2O4S/c1-7-13(20)16-6-9(18)12(19)11(16)15-17(7)14(21)8-4-2-3-5-10(8)22-15/h2-5,7,9,11-12,15,18-19H,6H2,1H3/t7-,9+,11+,12+,15+/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.21E+3n/an/an/an/an/an/a



Hebei University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase using DIG-labeled dNTPs as substrate after 1 hr by ELISA


Bioorg Med Chem Lett 26: 1738-41 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.049
BindingDB Entry DOI: 10.7270/Q2Q52RHF
More data for this
Ligand-Target Pair
Reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50152690
PNG
(CHEMBL3780227)
Show SMILES [H][C@]12[C@H](O)[C@H](O)CN1C(=O)CN1C(=O)c3ccccc3S[C@@]21[H] |r|
Show InChI InChI=1S/C14H14N2O4S/c17-8-5-15-10(18)6-16-13(20)7-3-1-2-4-9(7)21-14(16)11(15)12(8)19/h1-4,8,11-12,14,17,19H,5-6H2/t8-,11-,12-,14+/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.21E+3n/an/an/an/an/an/a



Hebei University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase using DIG-labeled dNTPs as substrate after 1 hr by ELISA


Bioorg Med Chem Lett 26: 1738-41 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.049
BindingDB Entry DOI: 10.7270/Q2Q52RHF
More data for this
Ligand-Target Pair
Reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50152689
PNG
(CHEMBL3780352)
Show SMILES [H][C@]12[C@H](O)[C@H](O)CN1C(=O)[C@H](C)N1C(=O)c3ccccc3S[C@@]21[H] |r|
Show InChI InChI=1S/C15H16N2O4S/c1-7-13(20)16-6-9(18)12(19)11(16)15-17(7)14(21)8-4-2-3-5-10(8)22-15/h2-5,7,9,11-12,15,18-19H,6H2,1H3/t7-,9+,11+,12+,15-/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.65E+3n/an/an/an/an/an/a



Hebei University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase using DIG-labeled dNTPs as substrate after 1 hr by ELISA


Bioorg Med Chem Lett 26: 1738-41 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.049
BindingDB Entry DOI: 10.7270/Q2Q52RHF
More data for this
Ligand-Target Pair
Reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50002692
PNG
((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Show SMILES Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O |r|
Show InChI InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.01E+4n/an/an/an/an/an/a



Hebei University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase using DIG-labeled dNTPs as substrate after 1 hr by ELISA


Bioorg Med Chem Lett 26: 1738-41 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.049
BindingDB Entry DOI: 10.7270/Q2Q52RHF
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%