Found 15 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50148269
(CHEMBL3770219)Show SMILES Cc1nn(C)c(C)c1Cc1nnc(o1)-c1cc(Cl)ccc1OC1CCNCC1 Show InChI InChI=1S/C20H24ClN5O2/c1-12-16(13(2)26(3)25-12)11-19-23-24-20(28-19)17-10-14(21)4-5-18(17)27-15-6-8-22-9-7-15/h4-5,10,15,22H,6-9,11H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50148267
(CHEMBL3770442)Show SMILES COc1cccc(Cc2noc(n2)-c2cc(Cl)ccc2OC2CCNCC2)c1 Show InChI InChI=1S/C21H22ClN3O3/c1-26-17-4-2-3-14(11-17)12-20-24-21(28-25-20)18-13-15(22)5-6-19(18)27-16-7-9-23-10-8-16/h2-6,11,13,16,23H,7-10,12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50148265
(CHEMBL3770815)Show SMILES COc1cccc(Cc2noc(n2)-c2ccc(Br)cc2OC2CCNCC2)c1 Show InChI InChI=1S/C21H22BrN3O3/c1-26-17-4-2-3-14(11-17)12-20-24-21(28-25-20)18-6-5-15(22)13-19(18)27-16-7-9-23-10-8-16/h2-6,11,13,16,23H,7-10,12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50135531
(CHEMBL3753053)Show SMILES COc1cccc(Cc2noc(n2)-c2ccc(Cl)cc2OC2CCNCC2)c1 Show InChI InChI=1S/C21H22ClN3O3/c1-26-17-4-2-3-14(11-17)12-20-24-21(28-25-20)18-6-5-15(22)13-19(18)27-16-7-9-23-10-8-16/h2-6,11,13,16,23H,7-10,12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50135701
(CHEMBL3754641)Show SMILES COc1cccc(Cc2noc(n2)-c2ccc(F)cc2OC2CCNCC2)c1 Show InChI InChI=1S/C12H21N2O/c1-11(2)14(3,4)8-9-15-12-6-5-7-13-10-12/h5-7,10-11H,8-9H2,1-4H3/q+1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50148266
(CHEMBL3770262)Show SMILES COc1cccc(Cc2noc(n2)-c2cc(C)ccc2OC2CCNCC2)c1 Show InChI InChI=1S/C22H25N3O3/c1-15-6-7-20(27-17-8-10-23-11-9-17)19(12-15)22-24-21(25-28-22)14-16-4-3-5-18(13-16)26-2/h3-7,12-13,17,23H,8-11,14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50148268
(CHEMBL3771033)Show SMILES COc1cccc(Cc2noc(n2)-c2cc(OC)ccc2OC2CCNCC2)c1 Show InChI InChI=1S/C22H25N3O4/c1-26-17-5-3-4-15(12-17)13-21-24-22(29-25-21)19-14-18(27-2)6-7-20(19)28-16-8-10-23-11-9-16/h3-7,12,14,16,23H,8-11,13H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50135702
(CHEMBL3753483)Show SMILES COc1cccc(Cc2noc(n2)-c2ccc(OC)cc2OC2CCNCC2)c1 Show InChI InChI=1S/C12H21N2O/c1-4-8-14(2,3)9-10-15-12-6-5-7-13-11-12/h5-7,11H,4,8-10H2,1-3H3/q+1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 860 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50135481
(CHEMBL3754110)Show InChI InChI=1S/C21H23N3O3/c1-25-17-6-4-5-15(13-17)14-20-23-21(27-24-20)18-7-2-3-8-19(18)26-16-9-11-22-12-10-16/h2-8,13,16,22H,9-12,14H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50423890
(CHEMBL2312449)Show InChI InChI=1S/C22H23NO4S/c1-25-17-6-4-5-15(13-17)14-26-22(24)21-20(27-16-9-11-23-12-10-16)18-7-2-3-8-19(18)28-21/h2-8,13,16,23H,9-12,14H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| PubMed
| 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50148264
(CHEMBL3771337)Show SMILES COc1cccc(Cc2noc(n2)-c2ccc(C)cc2OC2CCNCC2)c1 Show InChI InChI=1S/C22H25N3O3/c1-15-6-7-19(20(12-15)27-17-8-10-23-11-9-17)22-24-21(25-28-22)14-16-4-3-5-18(13-16)26-2/h3-7,12-13,17,23H,8-11,14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 4.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50148262
(CHEMBL3770859)Show SMILES COc1cccc(Cc2noc(n2)-c2cccc(OC)c2OC2CCNCC2)c1 Show InChI InChI=1S/C22H25N3O4/c1-26-17-6-3-5-15(13-17)14-20-24-22(29-25-20)18-7-4-8-19(27-2)21(18)28-16-9-11-23-12-10-16/h3-8,13,16,23H,9-12,14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 7.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50148263
(CHEMBL3770880)Show SMILES COc1cccc(Cc2noc(n2)-c2cccc(C)c2OC2CCNCC2)c1 Show InChI InChI=1S/C22H25N3O3/c1-15-5-3-8-19(21(15)27-17-9-11-23-12-10-17)22-24-20(25-28-22)14-16-6-4-7-18(13-16)26-2/h3-8,13,17,23H,9-12,14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 7.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50148261
(CHEMBL3770301)Show InChI InChI=1S/C20H23NO4/c1-23-17-6-4-5-15(13-17)14-24-20(22)18-7-2-3-8-19(18)25-16-9-11-21-12-10-16/h2-8,13,16,21H,9-12,14H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50148260
(CHEMBL3770735)Show InChI InChI=1S/C18H21NO4S/c1-21-15-4-2-3-13(11-15)12-22-18(20)17-16(7-10-24-17)23-14-5-8-19-9-6-14/h2-4,7,10-11,14,19H,5-6,8-9,12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human N-myristoyltransferase by fluorescence analysis |
Medchemcomm 6: 1761-1766 (2016)
BindingDB Entry DOI: 10.7270/Q2TB18R2 |
More data for this
Ligand-Target Pair | |
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