Affinity Data by PubMed id=26979485

PubMed code 26979485

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Pim1 kinase (unknown origin) using substrate S3 after 50 mins by HTRF assay				Bioorg Med Chem 24: 1889-97 (2016) Article DOI: 10.1016/j.bmc.2016.03.016 BindingDB Entry DOI: 10.7270/Q2XG9T05
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50364776 (CHEMBL1952141 \| CHEMBL1952329) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Pim1 kinase (unknown origin) using substrate S3 after 50 mins by HTRF assay				Bioorg Med Chem 24: 1889-97 (2016) Article DOI: 10.1016/j.bmc.2016.03.016 BindingDB Entry DOI: 10.7270/Q2XG9T05
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50155242 (CHEMBL3775858) Show SMILES Oc1ccc(Cl)c2ccc(Nc3ccccn3)nc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Pim1 kinase (unknown origin) using substrate S3 after 50 mins by HTRF assay				Bioorg Med Chem 24: 1889-97 (2016) Article DOI: 10.1016/j.bmc.2016.03.016 BindingDB Entry DOI: 10.7270/Q2XG9T05
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50155244 (CHEMBL3775001) Show SMILES N(c1ccccn1)c1ccc2ccccc2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Pim1 kinase (unknown origin) using substrate S3 after 50 mins by HTRF assay				Bioorg Med Chem 24: 1889-97 (2016) Article DOI: 10.1016/j.bmc.2016.03.016 BindingDB Entry DOI: 10.7270/Q2XG9T05
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50155243 (CHEMBL3774610) Show SMILES Oc1cccc2ccc(Sc3ccccn3)nc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Pim1 kinase (unknown origin) using substrate S3 after 50 mins by HTRF assay				Bioorg Med Chem 24: 1889-97 (2016) Article DOI: 10.1016/j.bmc.2016.03.016 BindingDB Entry DOI: 10.7270/Q2XG9T05
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%