Affinity Data by PubMed id=26985296

PubMed code 26985296

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50500878 (CHEMBL3799906) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Cologne Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin polymerization measured every 1 min for 60 mins by microplate reader analysis				ACS Med Chem Lett 7: 188-91 (2016) Article DOI: 10.1021/acsmedchemlett.5b00418 BindingDB Entry DOI: 10.7270/Q2D221NQ
University of Cologne Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta chain (Sus scrofa)	BDBM50500880 (CHEMBL3799435) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Cologne Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin polymerization measured every 1 min for 60 mins by microplate reader analysis				ACS Med Chem Lett 7: 188-91 (2016) Article DOI: 10.1021/acsmedchemlett.5b00418 BindingDB Entry DOI: 10.7270/Q2D221NQ
University of Cologne Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta chain (Sus scrofa)	BDBM50500879 (CHEMBL3800118) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
University of Cologne Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin polymerization measured every 1 min for 60 mins by microplate reader analysis				ACS Med Chem Lett 7: 188-91 (2016) Article DOI: 10.1021/acsmedchemlett.5b00418 BindingDB Entry DOI: 10.7270/Q2D221NQ
University of Cologne Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta chain (Sus scrofa)	BDBM50014846 ((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Cologne Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin polymerization measured every 1 min for 60 mins by microplate reader analysis				ACS Med Chem Lett 7: 188-91 (2016) Article DOI: 10.1021/acsmedchemlett.5b00418 BindingDB Entry DOI: 10.7270/Q2D221NQ
University of Cologne Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%