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PubMed code 26994638

Compile data set for download or QSAR
Found 27 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50092444
PNG
(CHEMBL3586121)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)-c1nnc(o1)-c1ccccc1O
Show InChI InChI=1S/C23H18N4O2/c1-13-11-18-19(12-14(13)2)25-21(24-18)15-7-9-16(10-8-15)22-26-27-23(29-22)17-5-3-4-6-20(17)28/h3-12,28H,1-2H3,(H,24,25)
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PubMed
n/an/a 2.14E+3n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160569
PNG
(CHEMBL3785671)
Show SMILES Clc1ccc(Nc2nnc(s2)-c2ccccc2Cl)cc1Cl
Show InChI InChI=1S/C14H8Cl3N3S/c15-10-4-2-1-3-9(10)13-19-20-14(21-13)18-8-5-6-11(16)12(17)7-8/h1-7H,(H,18,20)
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n/an/a 2.16E+3n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160575
PNG
(CHEMBL3786740)
Show SMILES COc1ccc(cc1)-c1nnc(Nc2ccc(Cl)c(Cl)c2)s1
Show InChI InChI=1S/C15H11Cl2N3OS/c1-21-11-5-2-9(3-6-11)14-19-20-15(22-14)18-10-4-7-12(16)13(17)8-10/h2-8H,1H3,(H,18,20)
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n/an/a 4.16E+3n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160567
PNG
(CHEMBL3787430)
Show SMILES Oc1cccc(\C=N/c2nc(cs2)-c2ccccc2)c1O
Show InChI InChI=1S/C16H12N2O2S/c19-14-8-4-7-12(15(14)20)9-17-16-18-13(10-21-16)11-5-2-1-3-6-11/h1-10,19-20H/b17-9-
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n/an/a 4.88E+3n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160574
PNG
(CHEMBL3785548)
Show SMILES Clc1ccc(Nc2nnc(s2)-c2ccccc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N3S/c15-11-7-6-10(8-12(11)16)17-14-19-18-13(20-14)9-4-2-1-3-5-9/h1-8H,(H,17,19)
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n/an/a 6.28E+3n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160570
PNG
(CHEMBL3787019)
Show SMILES Clc1ccc(Nc2nnc(s2)-c2ccc(Br)cc2)cc1Cl
Show InChI InChI=1S/C14H8BrCl2N3S/c15-9-3-1-8(2-4-9)13-19-20-14(21-13)18-10-5-6-11(16)12(17)7-10/h1-7H,(H,18,20)
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n/an/a 7.16E+3n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160576
PNG
(CHEMBL3787541)
Show SMILES Clc1ccccc1-c1nnc(Nc2cccc(Br)c2)s1
Show InChI InChI=1S/C14H9BrClN3S/c15-9-4-3-5-10(8-9)17-14-19-18-13(20-14)11-6-1-2-7-12(11)16/h1-8H,(H,17,19)
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n/an/a 8.96E+3n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160573
PNG
(CHEMBL3785397)
Show SMILES Cc1ccc(-c2nnc(Nc3ccc(Cl)c(Cl)c3)s2)c(C)c1
Show InChI InChI=1S/C16H13Cl2N3S/c1-9-3-5-12(10(2)7-9)15-20-21-16(22-15)19-11-4-6-13(17)14(18)8-11/h3-8H,1-2H3,(H,19,21)
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n/an/a 1.56E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160577
PNG
(CHEMBL3787234)
Show SMILES Cc1ccc(Nc2nnc(s2)-c2ccccc2Cl)cc1
Show InChI InChI=1S/C15H12ClN3S/c1-10-6-8-11(9-7-10)17-15-19-18-14(20-15)12-4-2-3-5-13(12)16/h2-9H,1H3,(H,17,19)
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n/an/a 1.67E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160579
PNG
(CHEMBL3785586)
Show SMILES Brc1ccc(cc1)-c1nnc(Nc2cccc(Br)c2)s1
Show InChI InChI=1S/C14H9Br2N3S/c15-10-6-4-9(5-7-10)13-18-19-14(20-13)17-12-3-1-2-11(16)8-12/h1-8H,(H,17,19)
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n/an/a 1.73E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160572
PNG
(CHEMBL3786744)
Show SMILES COc1cc(OC)cc(c1)-c1nnc(Nc2ccc(Cl)c(Cl)c2)s1
Show InChI InChI=1S/C16H13Cl2N3O2S/c1-22-11-5-9(6-12(8-11)23-2)15-20-21-16(24-15)19-10-3-4-13(17)14(18)7-10/h3-8H,1-2H3,(H,19,21)
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n/an/a 1.92E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160578
PNG
(CHEMBL3786665)
Show SMILES COc1ccc(Nc2nnc(s2)-c2ccccc2Cl)cc1
Show InChI InChI=1S/C15H12ClN3OS/c1-20-11-8-6-10(7-9-11)17-15-19-18-14(21-15)12-4-2-3-5-13(12)16/h2-9H,1H3,(H,17,19)
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n/an/a 2.26E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160571
PNG
(CHEMBL3787549)
Show SMILES COc1ccccc1-c1nnc(Nc2ccc(Cl)c(Cl)c2)s1
Show InChI InChI=1S/C15H11Cl2N3OS/c1-21-13-5-3-2-4-10(13)14-19-20-15(22-14)18-9-6-7-11(16)12(17)8-9/h2-8H,1H3,(H,18,20)
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n/an/a 2.26E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160587
PNG
(CHEMBL3786874)
Show SMILES Cc1ccc(Nc2nnc(s2)-c2ccc(cc2)C(C)(C)C)cc1
Show InChI InChI=1S/C19H21N3S/c1-13-5-11-16(12-6-13)20-18-22-21-17(23-18)14-7-9-15(10-8-14)19(2,3)4/h5-12H,1-4H3,(H,20,22)
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n/an/a 2.63E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160586
PNG
(CHEMBL225602)
Show SMILES Cc1ccc(Nc2nnc(s2)-c2ccc(Br)cc2)cc1
Show InChI InChI=1S/C15H12BrN3S/c1-10-2-8-13(9-3-10)17-15-19-18-14(20-15)11-4-6-12(16)7-5-11/h2-9H,1H3,(H,17,19)
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n/an/a 2.86E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160583
PNG
(CHEMBL3786304)
Show SMILES COc1ccc(-c2nnc(Nc3ccc(Br)cc3)s2)c(OC)c1
Show InChI InChI=1S/C16H14BrN3O2S/c1-21-12-7-8-13(14(9-12)22-2)15-19-20-16(23-15)18-11-5-3-10(17)4-6-11/h3-9H,1-2H3,(H,18,20)
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n/an/a 2.97E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160585
PNG
(CHEMBL3787317)
Show SMILES COc1cccc(Nc2nnc(s2)-c2ccc(Br)cc2)c1
Show InChI InChI=1S/C15H12BrN3OS/c1-20-13-4-2-3-12(9-13)17-15-19-18-14(21-15)10-5-7-11(16)8-6-10/h2-9H,1H3,(H,17,19)
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n/an/a 3.11E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160580
PNG
(CHEMBL3785812)
Show SMILES CC(C)(C)c1ccc(cc1)-c1nnc(Nc2ccc(Br)cc2)s1
Show InChI InChI=1S/C18H18BrN3S/c1-18(2,3)13-6-4-12(5-7-13)16-21-22-17(23-16)20-15-10-8-14(19)9-11-15/h4-11H,1-3H3,(H,20,22)
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n/an/a 3.22E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160590
PNG
(CHEMBL3787236)
Show SMILES Cc1ccc(Nc2nnc(s2)-c2ccc(C)cc2C)cc1
Show InChI InChI=1S/C17H17N3S/c1-11-4-7-14(8-5-11)18-17-20-19-16(21-17)15-9-6-12(2)10-13(15)3/h4-10H,1-3H3,(H,18,20)
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n/an/a 3.43E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160582
PNG
(CHEMBL3785959)
Show SMILES Cc1ccc(-c2nnc(Nc3cccc(Br)c3)s2)c(C)c1
Show InChI InChI=1S/C16H14BrN3S/c1-10-6-7-14(11(2)8-10)15-19-20-16(21-15)18-13-5-3-4-12(17)9-13/h3-9H,1-2H3,(H,18,20)
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n/an/a 3.61E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160591
PNG
(CHEMBL3785754)
Show SMILES COc1ccc(-c2nnc(Nc3ccc(C)cc3)s2)c(OC)c1
Show InChI InChI=1S/C17H17N3O2S/c1-11-4-6-12(7-5-11)18-17-20-19-16(23-17)14-9-8-13(21-2)10-15(14)22-3/h4-10H,1-3H3,(H,18,20)
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n/an/a 3.93E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160584
PNG
(CHEMBL225065)
Show SMILES Brc1ccc(cc1)-c1nnc(Nc2ccccc2)s1
Show InChI InChI=1S/C14H10BrN3S/c15-11-8-6-10(7-9-11)13-17-18-14(19-13)16-12-4-2-1-3-5-12/h1-9H,(H,16,18)
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PubMed
n/an/a 4.02E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160592
PNG
(CHEMBL225063)
Show SMILES Cc1ccc(Nc2nnc(s2)-c2ccccc2)cc1
Show InChI InChI=1S/C15H13N3S/c1-11-7-9-13(10-8-11)16-15-18-17-14(19-15)12-5-3-2-4-6-12/h2-10H,1H3,(H,16,18)
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n/an/a 4.84E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50008907
PNG
(D-Saccharic Acid 1,4-Lactone)
Show SMILES [H][C@@]1(OC(=O)[C@H](O)[C@H]1O)[C@H](O)C(O)=O |r|
Show InChI InChI=1S/C6H8O7/c7-1-2(8)6(12)13-4(1)3(9)5(10)11/h1-4,7-9H,(H,10,11)/t1-,2-,3+,4+/m1/s1
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n/an/a 4.84E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160581
PNG
(CHEMBL3785527)
Show SMILES COc1ccccc1-c1nnc(Nc2cccc(Br)c2)s1
Show InChI InChI=1S/C15H12BrN3OS/c1-20-13-8-3-2-7-12(13)14-18-19-15(21-14)17-11-6-4-5-10(16)9-11/h2-9H,1H3,(H,17,19)
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n/an/a 4.92E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160589
PNG
(CHEMBL3786989)
Show SMILES COc1cc(OC)cc(c1)-c1nnc(Nc2ccc(C)cc2)s1
Show InChI InChI=1S/C17H17N3O2S/c1-11-4-6-13(7-5-11)18-17-20-19-16(23-17)12-8-14(21-2)10-15(9-12)22-3/h4-10H,1-3H3,(H,18,20)
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n/an/a 5.03E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Bos taurus (Bovine))
BDBM50160588
PNG
(CHEMBL3785645)
Show SMILES COc1ccccc1-c1nnc(Nc2ccc(C)cc2)s1
Show InChI InChI=1S/C16H15N3OS/c1-11-7-9-12(10-8-11)17-16-19-18-15(21-16)13-5-3-4-6-14(13)20-2/h3-10H,1-2H3,(H,17,19)
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n/an/a 5.81E+4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...


Bioorg Med Chem 24: 1909-18 (2016)


Article DOI: 10.1016/j.bmc.2016.03.020
BindingDB Entry DOI: 10.7270/Q28917RB
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%