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PubMed code 27055940

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 11


(Homo sapiens (Human))
BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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Article
PubMed
n/an/a 370n/an/an/an/an/an/a



Nankai University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged human HDAC11 expressed in Sf9 cells using Ac-Arg-Gly-Lys(Ac)-AMC as substrate by fluorometric assay


Bioorg Med Chem Lett 26: 2434-7 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.116
BindingDB Entry DOI: 10.7270/Q27M09S1
More data for this
Ligand-Target Pair
Histone deacetylase 11


(Homo sapiens (Human))
BDBM50156642
PNG
(CHEMBL3792560)
Show SMILES OC[C@@H]1C[C@@H](CN1Cc1ccccc1)n1cc(\C=C\C(=O)NO)nn1 |r|
Show InChI InChI=1S/C17H21N5O3/c23-12-16-8-15(11-21(16)9-13-4-2-1-3-5-13)22-10-14(18-20-22)6-7-17(24)19-25/h1-7,10,15-16,23,25H,8-9,11-12H2,(H,19,24)/b7-6+/t15-,16-/m0/s1
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Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Nankai University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged human HDAC11 expressed in Sf9 cells using Ac-Arg-Gly-Lys(Ac)-AMC as substrate by fluorometric assay


Bioorg Med Chem Lett 26: 2434-7 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.116
BindingDB Entry DOI: 10.7270/Q27M09S1
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%