Found 39 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM94503
(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)Show InChI InChI=1S/C22H30N2O2S/c1-3-21(25)24(19-8-5-4-6-9-19)22(18-26-2)12-15-23(16-13-22)14-11-20-10-7-17-27-20/h4-10,17H,3,11-16,18H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| Purchase
DrugBank
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50008984
(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)Show InChI InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
PubMed
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228269
(CHEMBL178035)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(C)=O)CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C25H32N2O3/c1-3-24(29)27(23-12-8-5-9-13-23)25(20-30-21(2)28)15-18-26(19-16-25)17-14-22-10-6-4-7-11-22/h4-13H,3,14-20H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
Antimuscarinic activity on the acetylcholine-induced inhibition of contraction of guinea pig ileum which has Muscarinic acetylcholine receptor M2 sub... |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228255
(CHEMBL362439)Show SMILES CC(C)C(=O)OCC1(CCN(CCc2ccccc2)CC1)N(C(=O)C(C)C)c1ccccc1 Show InChI InChI=1S/C28H38N2O3/c1-22(2)26(31)30(25-13-9-6-10-14-25)28(21-33-27(32)23(3)4)16-19-29(20-17-28)18-15-24-11-7-5-8-12-24/h5-14,22-23H,15-21H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228260
(CHEMBL367286)Show SMILES CCCC(=O)OCC1(CCN(CCc2cccs2)CC1)N(C(=O)CCC)c1ccccc1 Show InChI InChI=1S/C26H36N2O3S/c1-3-9-24(29)28(22-11-6-5-7-12-22)26(21-31-25(30)10-4-2)15-18-27(19-16-26)17-14-23-13-8-20-32-23/h5-8,11-13,20H,3-4,9-10,14-19,21H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM83450
(ALFENTANIL | Alfentanil hydrochloride | MLS0023206...)Show SMILES CCC(=O)N(c1ccccc1)C1(COC)CCN(CCn2nnn(CC)c2=O)CC1 Show InChI InChI=1S/C21H32N6O3/c1-4-19(28)27(18-9-7-6-8-10-18)21(17-30-3)11-13-24(14-12-21)15-16-26-20(29)25(5-2)22-23-26/h6-10H,4-5,11-17H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
DrugBank
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
Antimuscarinic activity on the acetylcholine-induced inhibition of contraction of guinea pig ileum which has Muscarinic acetylcholine receptor M2 sub... |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228221
(CHEMBL366899)Show SMILES CCOC(=O)OCC1(CCN(CCc2cccs2)CC1)N(C(=O)CC)c1ccccc1 Show InChI InChI=1S/C24H32N2O4S/c1-3-22(27)26(20-9-6-5-7-10-20)24(19-30-23(28)29-4-2)13-16-25(17-14-24)15-12-21-11-8-18-31-21/h5-11,18H,3-4,12-17,19H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 9.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228217
(CHEMBL174694)Show SMILES CCOC(=O)OCC1(CCN(CCc2ccccc2)CC1)N(C(=O)CC)c1ccccc1 Show InChI InChI=1S/C26H34N2O4/c1-3-24(29)28(23-13-9-6-10-14-23)26(21-32-25(30)31-4-2)16-19-27(20-17-26)18-15-22-11-7-5-8-12-22/h5-14H,3-4,15-21H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228224
(CHEMBL367667)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(=O)OC)CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C25H32N2O4/c1-3-23(28)27(22-12-8-5-9-13-22)25(20-31-24(29)30-2)15-18-26(19-16-25)17-14-21-10-6-4-7-11-21/h4-13H,3,14-20H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228259
(CHEMBL426034)Show SMILES CC(=O)OCC1(CCN(CCc2ccccc2)CC1)N(C(C)=O)c1ccccc1 Show InChI InChI=1S/C24H30N2O3/c1-20(27)26(23-11-7-4-8-12-23)24(19-29-21(2)28)14-17-25(18-15-24)16-13-22-9-5-3-6-10-22/h3-12H,13-19H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228219
(CHEMBL178847)Show SMILES CC(=O)OCC1(CCN(CCc2cccs2)CC1)N(C(C)=O)c1ccccc1 Show InChI InChI=1S/C22H28N2O3S/c1-18(25)24(20-7-4-3-5-8-20)22(17-27-19(2)26)11-14-23(15-12-22)13-10-21-9-6-16-28-21/h3-9,16H,10-15,17H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228251
(CHEMBL176438)Show SMILES CCC(=O)OCC1(CCN(CCc2cccs2)CC1)N(C(=O)CC)c1ccccc1 Show InChI InChI=1S/C24H32N2O3S/c1-3-22(27)26(20-9-6-5-7-10-20)24(19-29-23(28)4-2)13-16-25(17-14-24)15-12-21-11-8-18-30-21/h5-11,18H,3-4,12-17,19H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228218
(CHEMBL368487)Show SMILES CCCC(=O)OCC1(CCN(CCc2ccccc2)CC1)N(C(=O)CCC)c1ccccc1 Show InChI InChI=1S/C28H38N2O3/c1-3-11-26(31)30(25-15-9-6-10-16-25)28(23-33-27(32)12-4-2)18-21-29(22-19-28)20-17-24-13-7-5-8-14-24/h5-10,13-16H,3-4,11-12,17-23H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
Antimuscarinic activity on the acetylcholine-induced inhibition of contraction of guinea pig ileum which has M2 muscarinic receptor subtype. |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228231
(CHEMBL174828)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(C)=O)CCN(CCc2cccs2)CC1 Show InChI InChI=1S/C23H30N2O3S/c1-3-22(27)25(20-8-5-4-6-9-20)23(18-28-19(2)26)12-15-24(16-13-23)14-11-21-10-7-17-29-21/h4-10,17H,3,11-16,18H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228225
(CHEMBL174758)Show SMILES CC(C)C(=O)OCC1(CCN(CCc2cccs2)CC1)N(C(=O)C(C)C)c1ccccc1 Show InChI InChI=1S/C26H36N2O3S/c1-20(2)24(29)28(22-9-6-5-7-10-22)26(19-31-25(30)21(3)4)13-16-27(17-14-26)15-12-23-11-8-18-32-23/h5-11,18,20-21H,12-17,19H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228230
(CHEMBL174947)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(=O)OC)CCN(CCc2cccs2)CC1 Show InChI InChI=1S/C23H30N2O4S/c1-3-21(26)25(19-8-5-4-6-9-19)23(18-29-22(27)28-2)12-15-24(16-13-23)14-11-20-10-7-17-30-20/h4-10,17H,3,11-16,18H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228264
(CHEMBL367661)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(=O)C(C)(C)C)CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C28H38N2O3/c1-5-25(31)30(24-14-10-7-11-15-24)28(22-33-26(32)27(2,3)4)17-20-29(21-18-28)19-16-23-12-8-6-9-13-23/h6-15H,5,16-22H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
Antimuscarinic activity on the acetylcholine-induced inhibition of contraction of guinea pig ileum which has M2 muscarinic receptor subtype. |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228253
(CHEMBL367968)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(=O)C(C)(C)C)CCN(CCc2cccs2)CC1 Show InChI InChI=1S/C26H36N2O3S/c1-5-23(29)28(21-10-7-6-8-11-21)26(20-31-24(30)25(2,3)4)14-17-27(18-15-26)16-13-22-12-9-19-32-22/h6-12,19H,5,13-18,20H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228256
(CHEMBL369412)Show SMILES CCC(=O)OCC1(CCN(CCc2ccccc2)CC1)N(C(C)=O)c1ccccc1 Show InChI InChI=1S/C25H32N2O3/c1-3-24(29)30-20-25(27(21(2)28)23-12-8-5-9-13-23)15-18-26(19-16-25)17-14-22-10-6-4-7-11-22/h4-13H,3,14-20H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228226
(CHEMBL172032)Show SMILES CCCC(=O)OCC1(CCN(CCn2ncnn2)CC1)N(C(=O)CCC)c1ccccc1 Show InChI InChI=1S/C23H34N6O3/c1-3-8-21(30)29(20-10-6-5-7-11-20)23(18-32-22(31)9-4-2)12-14-27(15-13-23)16-17-28-25-19-24-26-28/h5-7,10-11,19H,3-4,8-9,12-18H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228223
(CHEMBL369448)Show SMILES CCC(=O)OCC1(CCN(CCN2C(=O)c3ccccc3C2=O)CC1)N(C(=O)CC)c1ccccc1 Show InChI InChI=1S/C28H33N3O5/c1-3-24(32)31(21-10-6-5-7-11-21)28(20-36-25(33)4-2)14-16-29(17-15-28)18-19-30-26(34)22-12-8-9-13-23(22)27(30)35/h5-13H,3-4,14-20H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228254
(CHEMBL172910)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(=O)C(C)(C)C)CCN(CCn2ncnn2)CC1 Show InChI InChI=1S/C23H34N6O3/c1-5-20(30)29(19-9-7-6-8-10-19)23(17-32-21(31)22(2,3)4)11-13-27(14-12-23)15-16-28-25-18-24-26-28/h6-10,18H,5,11-17H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228268
(CHEMBL173971)Show SMILES CCOC(=O)OCC1(CCN(CCn2ncnn2)CC1)N(C(=O)CC)c1ccccc1 Show InChI InChI=1S/C21H30N6O4/c1-3-19(28)27(18-8-6-5-7-9-18)21(16-31-20(29)30-4-2)10-12-25(13-11-21)14-15-26-23-17-22-24-26/h5-9,17H,3-4,10-16H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228262
(CHEMBL172531)Show SMILES COC(C)C(=O)OCC1(CCN(CCc2cccs2)CC1)N(C(=O)C(C)OC)c1ccccc1 Show InChI InChI=1S/C26H36N2O5S/c1-20(31-3)24(29)28(22-9-6-5-7-10-22)26(19-33-25(30)21(2)32-4)13-16-27(17-14-26)15-12-23-11-8-18-34-23/h5-11,18,20-21H,12-17,19H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228263
(CHEMBL175126)Show SMILES COC(C)C(=O)OCC1(CCN(CCN2C(=O)c3ccccc3C2=O)CC1)N(C(=O)C(C)OC)c1ccccc1 Show InChI InChI=1S/C30H37N3O7/c1-21(38-3)26(34)33(23-10-6-5-7-11-23)30(20-40-29(37)22(2)39-4)14-16-31(17-15-30)18-19-32-27(35)24-12-8-9-13-25(24)28(32)36/h5-13,21-22H,14-20H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228250
(CHEMBL369455)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(=O)OC)CCN(CCn2ncnn2)CC1 Show InChI InChI=1S/C20H28N6O4/c1-3-18(27)26(17-7-5-4-6-8-17)20(15-30-19(28)29-2)9-11-24(12-10-20)13-14-25-22-16-21-23-25/h4-8,16H,3,9-15H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228252
(CHEMBL435340)Show SMILES CCn1nnn(CCN2CCC(COC(=O)C(C)C)(CC2)N(C(=O)C(C)C)c2ccccc2)c1=O Show InChI InChI=1S/C25H38N6O4/c1-6-29-24(34)30(27-26-29)17-16-28-14-12-25(13-15-28,18-35-23(33)20(4)5)31(22(32)19(2)3)21-10-8-7-9-11-21/h7-11,19-20H,6,12-18H2,1-5H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228265
(CHEMBL263783)Show SMILES CC(C)C(=O)OCC1(CCN(CCn2ncnn2)CC1)N(C(=O)C(C)C)c1ccccc1 Show InChI InChI=1S/C23H34N6O3/c1-18(2)21(30)29(20-8-6-5-7-9-20)23(16-32-22(31)19(3)4)10-12-27(13-11-23)14-15-28-25-17-24-26-28/h5-9,17-19H,10-16H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
Antimuscarinic activity on the acetylcholine-induced inhibition of contraction of guinea pig ileum which has Muscarinic acetylcholine receptor M2 |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228267
(CHEMBL177046)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(=O)OC)CCN(CCN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C27H31N3O6/c1-3-23(31)30(20-9-5-4-6-10-20)27(19-36-26(34)35-2)13-15-28(16-14-27)17-18-29-24(32)21-11-7-8-12-22(21)25(29)33/h4-12H,3,13-19H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
Antimuscarinic activity on the acetylcholine-induced inhibition of contraction of guinea pig ileum which has M2 muscarinic receptor subtype. |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228257
(CHEMBL172703)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(=O)OC)CCN(CCn2nnn(CC)c2=O)CC1 Show InChI InChI=1S/C22H32N6O5/c1-4-19(29)28(18-9-7-6-8-10-18)22(17-33-21(31)32-3)11-13-25(14-12-22)15-16-27-20(30)26(5-2)23-24-27/h6-10H,4-5,11-17H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228227
(CHEMBL174962)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(=O)C(C)(C)C)CCN(CCN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C30H37N3O5/c1-5-25(34)33(22-11-7-6-8-12-22)30(21-38-28(37)29(2,3)4)15-17-31(18-16-30)19-20-32-26(35)23-13-9-10-14-24(23)27(32)36/h6-14H,5,15-21H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228229
(CHEMBL174834)Show SMILES CC(C)C(=O)OCC1(CCN(CCN2C(=O)c3ccccc3C2=O)CC1)N(C(=O)C(C)C)c1ccccc1 Show InChI InChI=1S/C30H37N3O5/c1-21(2)26(34)33(23-10-6-5-7-11-23)30(20-38-29(37)22(3)4)14-16-31(17-15-30)18-19-32-27(35)24-12-8-9-13-25(24)28(32)36/h5-13,21-22H,14-20H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
Antimuscarinic activity on the acetylcholine-induced inhibition of contraction of guinea pig ileum which has M2 muscarinic receptor subtype. |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228266
(CHEMBL369871)Show SMILES CCCC(=O)OCC1(CCN(CCN2C(=O)c3ccccc3C2=O)CC1)N(C(=O)CCC)c1ccccc1 Show InChI InChI=1S/C30H37N3O5/c1-3-10-26(34)33(23-12-6-5-7-13-23)30(22-38-27(35)11-4-2)16-18-31(19-17-30)20-21-32-28(36)24-14-8-9-15-25(24)29(32)37/h5-9,12-15H,3-4,10-11,16-22H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
Antimuscarinic activity on the acetylcholine-induced inhibition of contraction of guinea pig ileum which has M2 muscarinic receptor subtype. |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228258
(CHEMBL172717)Show SMILES CCOC(=O)OCC1(CCN(CCN2C(=O)c3ccccc3C2=O)CC1)N(C(=O)CC)c1ccccc1 Show InChI InChI=1S/C28H33N3O6/c1-3-24(32)31(21-10-6-5-7-11-21)28(20-37-27(35)36-4-2)14-16-29(17-15-28)18-19-30-25(33)22-12-8-9-13-23(22)26(30)34/h5-13H,3-4,14-20H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228270
(CHEMBL178434)Show SMILES COC(C)C(=O)OCC1(CCN(CCc2ccccc2)CC1)N(C(=O)C(C)OC)c1ccccc1 Show InChI InChI=1S/C28H38N2O5/c1-22(33-3)26(31)30(25-13-9-6-10-14-25)28(21-35-27(32)23(2)34-4)16-19-29(20-17-28)18-15-24-11-7-5-8-12-24/h5-14,22-23H,15-21H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228222
(CHEMBL175148)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(C)=O)CCN(CCn2nnn(CC)c2=O)CC1 Show InChI InChI=1S/C22H32N6O4/c1-4-20(30)28(19-9-7-6-8-10-19)22(17-32-18(3)29)11-13-25(14-12-22)15-16-27-21(31)26(5-2)23-24-27/h6-10H,4-5,11-17H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228220
(CHEMBL174926)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(C)=O)CCN(CCN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C27H31N3O5/c1-3-24(32)30(21-9-5-4-6-10-21)27(19-35-20(2)31)13-15-28(16-14-27)17-18-29-25(33)22-11-7-8-12-23(22)26(29)34/h4-12H,3,13-19H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228228
(CHEMBL366436)Show SMILES CCC(=O)N(c1ccccc1)C1(COC(C)=O)CCN(CCn2ncnn2)CC1 Show InChI InChI=1S/C20H28N6O3/c1-3-19(28)26(18-7-5-4-6-8-18)20(15-29-17(2)27)9-11-24(12-10-20)13-14-25-22-16-21-23-25/h4-8,16H,3,9-15H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50228261
(CHEMBL176618)Show SMILES CCC(=O)OCC1(CCN(CCn2nnn(CC)c2=O)CC1)N(C(=O)CC)c1ccccc1 Show InChI InChI=1S/C23H34N6O4/c1-4-20(30)29(19-10-8-7-9-11-19)23(18-33-21(31)5-2)12-14-26(15-13-23)16-17-28-22(32)27(6-3)24-25-28/h7-11H,4-6,12-18H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anaquest Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro affinity to displace [3H]naloxone from opioid receptor in freshly prepared rat brain homogenates |
J Med Chem 32: 968-74 (1989)
BindingDB Entry DOI: 10.7270/Q2XG9TBN |
More data for this
Ligand-Target Pair | |
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