Affinity Data by PubMed id=27123901

PubMed code 27123901

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50341243 ((3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of PDK1 (unknown origin)				Eur J Med Chem 118: 47-63 (2016) Article DOI: 10.1016/j.ejmech.2016.04.003 BindingDB Entry DOI: 10.7270/Q2F191NB
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50184998 (CHEMBL3823242) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of PDK1 (unknown origin)				Eur J Med Chem 118: 47-63 (2016) Article DOI: 10.1016/j.ejmech.2016.04.003 BindingDB Entry DOI: 10.7270/Q2F191NB
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50185001 (CHEMBL3824119 \| US10351548, Compound IB35) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of PDK1 (unknown origin) by FRET-based Z-lyte assay				Eur J Med Chem 118: 47-63 (2016) Article DOI: 10.1016/j.ejmech.2016.04.003 BindingDB Entry DOI: 10.7270/Q2F191NB
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50185000 (CHEMBL3823844 \| US10351548, Compound SA16) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	416	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of PDK1 (unknown origin) by FRET-based Z-lyte assay				Eur J Med Chem 118: 47-63 (2016) Article DOI: 10.1016/j.ejmech.2016.04.003 BindingDB Entry DOI: 10.7270/Q2F191NB
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50185003 (CHEMBL3824264 \| US10351548, Compound JJ31) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	512	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of PDK1 (unknown origin) by FRET-based Z-lyte assay				Eur J Med Chem 118: 47-63 (2016) Article DOI: 10.1016/j.ejmech.2016.04.003 BindingDB Entry DOI: 10.7270/Q2F191NB
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50184999 (CHEMBL3823622 \| US10351548, Compound SA23) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of PDK1 (unknown origin) by FRET-based Z-lyte assay				Eur J Med Chem 118: 47-63 (2016) Article DOI: 10.1016/j.ejmech.2016.04.003 BindingDB Entry DOI: 10.7270/Q2F191NB
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50185002 (CHEMBL3822974 \| US10351548, Compound IB32) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of PDK1 (unknown origin) by FRET-based Z-lyte assay				Eur J Med Chem 118: 47-63 (2016) Article DOI: 10.1016/j.ejmech.2016.04.003 BindingDB Entry DOI: 10.7270/Q2F191NB
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%