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PubMed code 27173797

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptide deformylase


(Staphylococcus aureus)		BDBM50174530
PNG
(CHEMBL3808584)
Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CC1CCCC1)CN(O)C=O)C(=O)N1CCC(CC1)NCc1cc(F)c(F)cc1F |r|
Show InChI InChI=1S/C28H41F3N4O4/c1-28(2,3)25(33-26(37)20(16-35(39)17-36)12-18-6-4-5-7-18)27(38)34-10-8-21(9-11-34)32-15-19-13-23(30)24(31)14-22(19)29/h13-14,17-18,20-21,25,32,39H,4-12,15-16H2,1-3H3,(H,33,37)/t20-,25-/m1/s1
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PC cid
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Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Research Laboratories ILDONG Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus PDF using formyl-methionine-alanine-serine as substrate assessed as increase in NADH levels by microtiter ELISA

Bioorg Med Chem Lett 26: 3148-52 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.086
BindingDB Entry DOI: 10.7270/Q2KH0Q7W
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus)		BDBM50174529
PNG
(BB-83698 | CHEMBL1614662)
Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CC1CCCC1)CN(O)C=O)C(=O)N1CCN(Cc2ccc3OCOc3c2)CC1 |r|
Show InChI InChI=1S/C28H42N4O6/c1-28(2,3)25(29-26(34)22(17-32(36)18-33)14-20-6-4-5-7-20)27(35)31-12-10-30(11-13-31)16-21-8-9-23-24(15-21)38-19-37-23/h8-9,15,18,20,22,25,36H,4-7,10-14,16-17,19H2,1-3H3,(H,29,34)/t22-,25-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Research Laboratories ILDONG Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus PDF using formyl-methionine-alanine-serine as substrate assessed as increase in NADH levels by microtiter ELISA

Bioorg Med Chem Lett 26: 3148-52 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.086
BindingDB Entry DOI: 10.7270/Q2KH0Q7W
More data for this
Ligand-Target Pair
Peptide deformylase


(Staphylococcus aureus)		BDBM50174531
PNG
(CHEMBL3809060)
Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CC1CCCC1)CN(O)C=O)C(=O)N1CCC(CC1)NCc1ccc(cc1)C#N |r|
Show InChI InChI=1S/C29H43N5O4/c1-29(2,3)26(32-27(36)24(19-34(38)20-35)16-21-6-4-5-7-21)28(37)33-14-12-25(13-15-33)31-18-23-10-8-22(17-30)9-11-23/h8-11,20-21,24-26,31,38H,4-7,12-16,18-19H2,1-3H3,(H,32,36)/t24-,26-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Research Laboratories ILDONG Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus PDF using formyl-methionine-alanine-serine as substrate assessed as increase in NADH levels by microtiter ELISA

Bioorg Med Chem Lett 26: 3148-52 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.086
BindingDB Entry DOI: 10.7270/Q2KH0Q7W
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%