Affinity Data by PubMed id=27474918

PubMed code 27474918

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50354485 (CHEMBL412298) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of wild type Abl (unknown origin)				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM13216 (BMS-354825 \| CHEMBL1421 \| DASATINIB \| N-(2-Chloro-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of wild type recombinant human Abl using abtide as substrate by [gamma-32P]ATP based assay				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50206297 (CHEMBL3911525) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of recombinant human Src using KVEKIGEGTYGVVYK as substrate by [gamma-32P]ATP based assay				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50206301 (CHEMBL3954137) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of wild type recombinant human Abl using abtide as substrate by [gamma-32P]ATP based assay				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50206297 (CHEMBL3911525) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of wild type recombinant human Abl using abtide as substrate by [gamma-32P]ATP based assay				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50206296 (CHEMBL3904850) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of recombinant human Src using KVEKIGEGTYGVVYK as substrate by [gamma-32P]ATP based assay				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50206296 (CHEMBL3904850) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of wild type recombinant human Abl using abtide as substrate by [gamma-32P]ATP based assay				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50206298 (CHEMBL3917521) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of wild type recombinant human Abl using abtide as substrate by [gamma-32P]ATP based assay				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50206300 (CHEMBL3967164) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of wild type recombinant human Abl using abtide as substrate by [gamma-32P]ATP based assay				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50206301 (CHEMBL3954137) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of recombinant human Src using KVEKIGEGTYGVVYK as substrate by [gamma-32P]ATP based assay				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50206302 (CHEMBL3983676) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of wild type recombinant human Abl using abtide as substrate by [gamma-32P]ATP based assay				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50206299 (CHEMBL3908573) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of wild type recombinant human Abl using abtide as substrate by [gamma-32P]ATP based assay				Eur J Med Chem 123: 1-13 (2016) Article DOI: 10.1016/j.ejmech.2016.07.034 BindingDB Entry DOI: 10.7270/Q2ZP484T
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%