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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sphingosine-1-phosphate lyase 1 (Rattus norvegicus) | BDBM50187501 (CHEMBL3827445) | PDB UniProtKB/SwissProt GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) Curated by ChEMBL | Assay Description Competitive inhibition of rat S1PL in presence of D(+)-erythro-sphinganine-1-phosphate measured after 15 mins by Dixon plot analysis | Bioorg Med Chem 24: 4381-4389 (2016) Article DOI: 10.1016/j.bmc.2016.07.033 BindingDB Entry DOI: 10.7270/Q2862JDX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human)) | BDBM50018286 (CHEMBL3290335) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) Curated by ChEMBL | Assay Description Inhibition of human S1PL using RBM13 as substrate measured after 1 hr by fluorogenic assay | Bioorg Med Chem 24: 4381-4389 (2016) Article DOI: 10.1016/j.bmc.2016.07.033 BindingDB Entry DOI: 10.7270/Q2862JDX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
