Affinity Data by PubMed id=27517809

PubMed code 27517809

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Pteridine reductase 1 (Leishmania major)	BDBM50207231 (CHEMBL3905744) Show SMILES Oc1c(Br)cc(Cl)cc1\C=C1/SC(=O)NC1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Estadual de Feira de Santana Curated by ChEMBL					Assay Description Inhibition of Leishmania major recombinant N-terminal hexa-His tagged PTR1 catalytic activity expressed in Escherichia coli BL21(DE3) using biopterin...				Eur J Med Chem 123: 639-648 (2016) Article DOI: 10.1016/j.ejmech.2016.07.060 BindingDB Entry DOI: 10.7270/Q23B624W
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50207232 (CHEMBL3933757) Show SMILES Oc1ccc(Cl)cc1\C=C1/SC(=O)NC1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Estadual de Feira de Santana Curated by ChEMBL					Assay Description Inhibition of Leishmania major recombinant N-terminal hexa-His tagged PTR1 catalytic activity expressed in Escherichia coli BL21(DE3) using biopterin...				Eur J Med Chem 123: 639-648 (2016) Article DOI: 10.1016/j.ejmech.2016.07.060 BindingDB Entry DOI: 10.7270/Q23B624W
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50207230 (CHEMBL3942723) Show SMILES Fc1cccc(Br)c1\C=C1/SC(=O)NC1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.89E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Estadual de Feira de Santana Curated by ChEMBL					Assay Description Inhibition of Leishmania major recombinant N-terminal hexa-His tagged PTR1 catalytic activity expressed in Escherichia coli BL21(DE3) using biopterin...				Eur J Med Chem 123: 639-648 (2016) Article DOI: 10.1016/j.ejmech.2016.07.060 BindingDB Entry DOI: 10.7270/Q23B624W
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%