Affinity Data by PubMed id=27576294

PubMed code 27576294

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50198326 (CHEMBL3908835) Show SMILES CCc1ccc(NCc2cccc(CNc3ccc(CC)cc3)n2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Displacement of biotinylated-TN14003 from CXCR4 in human MDA-MB-231 cells assessed as reduction in fluorescence preincubated for 10 mins followed by ...				Bioorg Med Chem 24: 5052-5060 (2016) Article DOI: 10.1016/j.bmc.2016.08.018 BindingDB Entry DOI: 10.7270/Q2WS8W7J
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50198327 (CHEMBL3948266) Show SMILES C(N1CCOCC1)c1cccc(CN2CCOCC2)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Displacement of biotinylated-TN14003 from CXCR4 in human MDA-MB-231 cells assessed as reduction in fluorescence preincubated for 10 mins followed by ...				Bioorg Med Chem 24: 5052-5060 (2016) Article DOI: 10.1016/j.bmc.2016.08.018 BindingDB Entry DOI: 10.7270/Q2WS8W7J
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%