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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human)) | BDBM50193033 (CHEMBL3902260) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Japan Tobacco Inc. Curated by ChEMBL | Assay Description Inhibition of PI3Kalpha (unknown origin) preincubated prior addition of PIP2 as substrate and ATP measured after 30 mins by HTRF assay | ACS Med Chem Lett 7: 919-923 (2016) Article DOI: 10.1021/acsmedchemlett.6b00232 BindingDB Entry DOI: 10.7270/Q23X88M8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM50193033 (CHEMBL3902260) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Japan Tobacco Inc. Curated by ChEMBL | Assay Description Inhibition of PI3Kbeta (unknown origin) preincubated prior addition of PIP2 as substrate and ATP measured after 30 mins by HTRF assay | ACS Med Chem Lett 7: 919-923 (2016) Article DOI: 10.1021/acsmedchemlett.6b00232 BindingDB Entry DOI: 10.7270/Q23X88M8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
