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PubMed code 28045490

Compile data set for download or QSAR
Found 7 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein kinase C iota type


(Homo sapiens (Human))		BDBM218807
PNG
(PS432)
Show SMILES CCOC(=O)C1=C(O)C(=O)N(C1c1ccc(o1)-c1ccc(Cl)cc1)c1nc2ccc(C)cc2s1 |c:5|
Show InChI InChI=1S/C25H19ClN2O5S/c1-3-32-24(31)20-21(18-11-10-17(33-18)14-5-7-15(26)8-6-14)28(23(30)22(20)29)25-27-16-9-4-13(2)12-19(16)34-25/h4-12,21,29H,3H2,1-2H3
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UniChem
Article
PubMed
n/an/a 1.69E+4n/an/an/an/a7.4n/a



Universitätsklinikum Frankfurt



Assay Description
Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2...

ACS Chem Biol 12: 564-573 (2017)


Article DOI: 10.1021/acschembio.6b00827
BindingDB Entry DOI: 10.7270/Q2J96575
More data for this
Ligand-Target Pair
Protein kinase C zeta type


(Homo sapiens (Human))		BDBM218806
PNG
(PS267)
Show SMILES CCOC(=O)C1=C(O)C(=O)N(C1c1cccs1)c1nc2ccc(Cl)cc2s1 |c:5|
Show InChI InChI=1S/C18H13ClN2O4S2/c1-2-25-17(24)13-14(11-4-3-7-26-11)21(16(23)15(13)22)18-20-10-6-5-9(19)8-12(10)27-18/h3-8,14,22H,2H2,1H3
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MMDB

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UniProtKB/SwissProt

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PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 1.78E+4n/an/an/an/a7.4n/a



Universitätsklinikum Frankfurt



Assay Description
Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2...

ACS Chem Biol 12: 564-573 (2017)


Article DOI: 10.1021/acschembio.6b00827
BindingDB Entry DOI: 10.7270/Q2J96575
More data for this
Ligand-Target Pair
Protein kinase C zeta type


(Homo sapiens (Human))		BDBM218807
PNG
(PS432)
Show SMILES CCOC(=O)C1=C(O)C(=O)N(C1c1ccc(o1)-c1ccc(Cl)cc1)c1nc2ccc(C)cc2s1 |c:5|
Show InChI InChI=1S/C25H19ClN2O5S/c1-3-32-24(31)20-21(18-11-10-17(33-18)14-5-7-15(26)8-6-14)28(23(30)22(20)29)25-27-16-9-4-13(2)12-19(16)34-25/h4-12,21,29H,3H2,1-2H3
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.85E+4n/an/an/an/a7.4n/a



Universitätsklinikum Frankfurt



Assay Description
Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2...

ACS Chem Biol 12: 564-573 (2017)


Article DOI: 10.1021/acschembio.6b00827
BindingDB Entry DOI: 10.7270/Q2J96575
More data for this
Ligand-Target Pair
Protein kinase C zeta type


(Homo sapiens (Human))		BDBM218805
PNG
(PS212)
Show SMILES CCOC(=O)C1=C(O)C(=O)N(C1c1ccc(Cl)cc1)c1nc2ccc(Cl)cc2[nH]1 |c:5|
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UniChem
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PubMed
n/an/a 2.05E+4n/an/an/an/a7.4n/a



Universitätsklinikum Frankfurt



Assay Description
Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2...

ACS Chem Biol 12: 564-573 (2017)


Article DOI: 10.1021/acschembio.6b00827
BindingDB Entry DOI: 10.7270/Q2J96575
More data for this
Ligand-Target Pair
Protein kinase C iota type


(Homo sapiens (Human))		BDBM218806
PNG
(PS267)
Show SMILES CCOC(=O)C1=C(O)C(=O)N(C1c1cccs1)c1nc2ccc(Cl)cc2s1 |c:5|
Show InChI InChI=1S/C18H13ClN2O4S2/c1-2-25-17(24)13-14(11-4-3-7-26-11)21(16(23)15(13)22)18-20-10-6-5-9(19)8-12(10)27-18/h3-8,14,22H,2H2,1H3
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antibodypedia
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PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 3.64E+4n/an/an/an/a7.4n/a



Universitätsklinikum Frankfurt



Assay Description
Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2...

ACS Chem Biol 12: 564-573 (2017)


Article DOI: 10.1021/acschembio.6b00827
BindingDB Entry DOI: 10.7270/Q2J96575
More data for this
Ligand-Target Pair
Protein kinase C iota type


(Homo sapiens (Human))		BDBM218805
PNG
(PS212)
Show SMILES CCOC(=O)C1=C(O)C(=O)N(C1c1ccc(Cl)cc1)c1nc2ccc(Cl)cc2[nH]1 |c:5|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.32E+4n/an/an/an/a7.4n/a



Universitätsklinikum Frankfurt



Assay Description
Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2...

ACS Chem Biol 12: 564-573 (2017)


Article DOI: 10.1021/acschembio.6b00827
BindingDB Entry DOI: 10.7270/Q2J96575
More data for this
Ligand-Target Pair
Protein kinase C zeta type


(Homo sapiens (Human))		BDBM218804
PNG
(PS312)
Show SMILES CCOC(=O)C1=C(O)C(=O)N(C1c1ccccc1)c1nc2ccc(Cl)cc2[nH]1 |c:5|
PDB
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PC cid
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UniChem
Article
PubMed
n/an/a 4.41E+4n/an/an/an/a7.4n/a



Universitätsklinikum Frankfurt



Assay Description
Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2...

ACS Chem Biol 12: 564-573 (2017)


Article DOI: 10.1021/acschembio.6b00827
BindingDB Entry DOI: 10.7270/Q2J96575
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%