Affinity Data by PubMed id=28099811

PubMed code 28099811

Found 23 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232949 (CHEMBL4100901) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232967 (CHEMBL4104898) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232952 (CHEMBL4084446) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232947 (CHEMBL4097540) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232950 (CHEMBL4093184) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232958 (CHEMBL4067285) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232951 (CHEMBL4092200) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232955 (CHEMBL4070356) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232961 (CHEMBL4097188) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232962 (CHEMBL4079174) Show SMILES CNc1nc(Nc2ccccc2)nc(OCC(F)(F)C(F)F)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232963 (CHEMBL4065523) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232954 (CHEMBL4096577) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232957 (CHEMBL4080996) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232960 (CHEMBL4087035) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in forskolin-stimulated basolateral membrane permeabilized FRT cells co-expressing YFP assessed as increase in sho...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232962 (CHEMBL4079174) Show SMILES CNc1nc(Nc2ccccc2)nc(OCC(F)(F)C(F)F)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in forskolin-stimulated basolateral membrane permeabilized FRT cells co-expressing YFP assessed as increase in sho...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232965 (CHEMBL4078552) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232948 (CHEMBL4074144) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232960 (CHEMBL4087035) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232966 (CHEMBL4070362) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232956 (CHEMBL4097536) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232959 (CHEMBL4094736) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232964 (CHEMBL4071412) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50232953 (CHEMBL4062768) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP assessed as increase in forskolin-stimulated iodide influx measured after 10 mins f...				J Med Chem 60: 1210-1218 (2017) Article DOI: 10.1021/acs.jmedchem.6b01792 BindingDB Entry DOI: 10.7270/Q2ZC8540
University of California Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%