Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50234486 (Melophlin C) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of PTP1B (unknown origin) using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins | Bioorg Med Chem Lett 27: 999-1002 (2017) Article DOI: 10.1016/j.bmcl.2016.12.077 BindingDB Entry DOI: 10.7270/Q2FT8P98 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
