Affinity Data by PubMed id=2824774

PubMed code 2824774

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50405507 (CHEMBL70193) Show SMILES CCC[n+]1cccc2C3CCCC(O)C3CCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
University of Lausanne Curated by ChEMBL					Assay Description Binding affinity against sigma receptor				J Med Chem 30: 2175-81 (1988) BindingDB Entry DOI: 10.7270/Q2FF3TJC
University of Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50405506 (CHEMBL69826) Show SMILES OC1CCC2CCc3c(ccc[n+]3Cc3ccccc3)C2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+7	n/a	n/a	n/a	n/a	n/a	n/a
University of Lausanne Curated by ChEMBL					Assay Description Binding affinity against sigma receptor				J Med Chem 30: 2175-81 (1988) BindingDB Entry DOI: 10.7270/Q2FF3TJC
University of Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50405506 (CHEMBL69826) Show SMILES OC1CCC2CCc3c(ccc[n+]3Cc3ccccc3)C2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.88E+8	n/a	n/a	n/a	n/a	n/a	n/a
University of Lausanne Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperone				J Med Chem 30: 2175-81 (1988) BindingDB Entry DOI: 10.7270/Q2FF3TJC
University of Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%