Affinity Data by PubMed id=28371664

PubMed code 28371664

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair				3D Structure (crystal)
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222423 (5-(3-chlorobenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1cccc(Cl)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222422 (5-(2-chlorobenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1ccccc1Cl Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222414 (5-(2-methylbenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1ccccc1C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222413 (5-(benzoyl)-4-methyl-1,3,4,5-tetrahydro-2H-1,5-ben...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222421 (5-(4-fluorobenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1ccc(F)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222415 (5-(3-methylbenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1cccc(C)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222424 (5-(4-chlorobenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1ccc(Cl)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222418 (5-(4-methoxybenzoyl)-4-methyl-1,3,4,5-tetrahydro-2...) Show SMILES COc1ccc(cc1)C(=O)N1C(C)CC(=O)Nc2ccccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222426 (5-(4-bromobenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H-...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1ccc(Br)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222420 (5-(3-fluorobenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1cccc(F)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222417 (5-(3-methoxybenzoyl)-4-methyl-1,3,4,5-tetrahydro-2...) Show SMILES COc1cccc(c1)C(=O)N1C(C)CC(=O)Nc2ccccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222425 (5-(2-bromobenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H-...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1ccccc1Br Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222419 (5-(2-fluorobenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1ccccc1F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM222416 (5-(4-methylbenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H...) Show SMILES CC1CC(=O)Nc2ccccc2N1C(=O)c1ccc(C)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science					Assay Description The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...				Bioorg Chem 72: 74-79 (2017) Article DOI: 10.1016/j.bioorg.2017.03.013 BindingDB Entry DOI: 10.7270/Q28K77XM
Birla Institute of Technology & Science					More data for this Ligand-Target Pair

* indicates data uncertainty>20%