Affinity Data by PubMed id=28651979

PubMed code 28651979

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50021574 (BMS-907351 \| CABOZANTINIB \| CHEBI:72317 \| Cabomety...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0350	n/a	n/a	n/a	n/a	n/a	n/a
School of Medicine, Nankai University, 94 Weijin Road, Tianjin 300071, China; Tianjin International S& T Cooperation Base, 94 Weijin Road, Tianjin 300071, China. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 phosphorylation (unknown origin)				Bioorg Med Chem Lett 27: 3231-3237 (2017) Article DOI: 10.1016/j.bmcl.2017.06.041 BindingDB Entry DOI: 10.7270/Q2JS9SW3
					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50268674 (CHEMBL4078060) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
School of Medicine, Nankai University, 94 Weijin Road, Tianjin 300071, China; Tianjin International S& T Cooperation Base, 94 Weijin Road, Tianjin 300071, China. Curated by ChEMBL					Assay Description Inhibition of human CDK9/CyclinT1 by enzymatic radiometric assay				Bioorg Med Chem Lett 27: 3231-3237 (2017) Article DOI: 10.1016/j.bmcl.2017.06.041 BindingDB Entry DOI: 10.7270/Q2JS9SW3
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D3 (Homo sapiens (Human))	BDBM148264 (7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
School of Medicine, Nankai University, 94 Weijin Road, Tianjin 300071, China; Tianjin International S& T Cooperation Base, 94 Weijin Road, Tianjin 300071, China. Curated by ChEMBL					Assay Description Inhibition of human CDK4/CyclinD3 by enzymatic radiometric assay				Bioorg Med Chem Lett 27: 3231-3237 (2017) Article DOI: 10.1016/j.bmcl.2017.06.041 BindingDB Entry DOI: 10.7270/Q2JS9SW3
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D3 (Homo sapiens (Human))	BDBM50268674 (CHEMBL4078060) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
School of Medicine, Nankai University, 94 Weijin Road, Tianjin 300071, China; Tianjin International S& T Cooperation Base, 94 Weijin Road, Tianjin 300071, China. Curated by ChEMBL					Assay Description Inhibition of human CDK4/CyclinD3 by enzymatic radiometric assay				Bioorg Med Chem Lett 27: 3231-3237 (2017) Article DOI: 10.1016/j.bmcl.2017.06.041 BindingDB Entry DOI: 10.7270/Q2JS9SW3
					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM148264 (7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
School of Medicine, Nankai University, 94 Weijin Road, Tianjin 300071, China; Tianjin International S& T Cooperation Base, 94 Weijin Road, Tianjin 300071, China. Curated by ChEMBL					Assay Description Inhibition of human CDK9/CyclinT1 by enzymatic radiometric assay				Bioorg Med Chem Lett 27: 3231-3237 (2017) Article DOI: 10.1016/j.bmcl.2017.06.041 BindingDB Entry DOI: 10.7270/Q2JS9SW3
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50268674 (CHEMBL4078060) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
School of Medicine, Nankai University, 94 Weijin Road, Tianjin 300071, China; Tianjin International S& T Cooperation Base, 94 Weijin Road, Tianjin 300071, China. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 by enzymatic radiometric assay				Bioorg Med Chem Lett 27: 3231-3237 (2017) Article DOI: 10.1016/j.bmcl.2017.06.041 BindingDB Entry DOI: 10.7270/Q2JS9SW3
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%