Affinity Data by PubMed id=29042224

PubMed code 29042224

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosinase precursor (Danio rerio)	BDBM69688 (5,7-Dihydroxy-4-phenyl-chromen-2-one \| 5,7-bis(oxi...) Show SMILES Oc1cc(O)c2c(cc(=O)oc2c1)-c1ccccc1 Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Nis Curated by ChEMBL					Assay Description Inhibition of zebrafish embryo tyrosinase assessed as melanin production after 48 hrs				Bioorg Med Chem 25: 6286-6296 (2017) Article DOI: 10.1016/j.bmc.2017.09.021 BindingDB Entry DOI: 10.7270/Q28G8P7C
University of Nis Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase precursor (Danio rerio)	BDBM69688 (5,7-Dihydroxy-4-phenyl-chromen-2-one \| 5,7-bis(oxi...) Show SMILES Oc1cc(O)c2c(cc(=O)oc2c1)-c1ccccc1 Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Nis Curated by ChEMBL					Assay Description Inhibition of zebrafish embryo tyrosinase assessed as residual activity after 48 hrs				Bioorg Med Chem 25: 6286-6296 (2017) Article DOI: 10.1016/j.bmc.2017.09.021 BindingDB Entry DOI: 10.7270/Q28G8P7C
University of Nis Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase precursor (Danio rerio)	BDBM50104891 (7-Hydroxy-4-phenyl-chromen-2-one \| 7-hydroxy-4-phe...) Show SMILES Oc1ccc2c(cc(=O)oc2c1)-c1ccccc1 Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Nis Curated by ChEMBL					Assay Description Inhibition of zebrafish embryo tyrosinase assessed as melanin production after 48 hrs				Bioorg Med Chem 25: 6286-6296 (2017) Article DOI: 10.1016/j.bmc.2017.09.021 BindingDB Entry DOI: 10.7270/Q28G8P7C
University of Nis Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase precursor (Danio rerio)	BDBM50104891 (7-Hydroxy-4-phenyl-chromen-2-one \| 7-hydroxy-4-phe...) Show SMILES Oc1ccc2c(cc(=O)oc2c1)-c1ccccc1 Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Nis Curated by ChEMBL					Assay Description Inhibition of zebrafish embryo tyrosinase assessed as residual activity after 48 hrs				Bioorg Med Chem 25: 6286-6296 (2017) Article DOI: 10.1016/j.bmc.2017.09.021 BindingDB Entry DOI: 10.7270/Q28G8P7C
University of Nis Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase precursor (Danio rerio)	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.09E+7	n/a	n/a	n/a	n/a	n/a	n/a
University of Nis Curated by ChEMBL					Assay Description Inhibition of zebrafish embryo tyrosinase assessed as melanin production after 48 hrs				Bioorg Med Chem 25: 6286-6296 (2017) Article DOI: 10.1016/j.bmc.2017.09.021 BindingDB Entry DOI: 10.7270/Q28G8P7C
University of Nis Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase precursor (Danio rerio)	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.43E+7	n/a	n/a	n/a	n/a	n/a	n/a
University of Nis Curated by ChEMBL					Assay Description Inhibition of zebrafish embryo tyrosinase assessed as residual activity after 48 hrs				Bioorg Med Chem 25: 6286-6296 (2017) Article DOI: 10.1016/j.bmc.2017.09.021 BindingDB Entry DOI: 10.7270/Q28G8P7C
University of Nis Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%