Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Envelope glycoprotein (Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zair...) | BDBM50247471 (CHEMBL558805) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.30E+6 | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Binding affinity to Ebola virus Zaire Mayinga-76 recombinant GP protein by SYPRO orange dye-based fluorescence assay | J Med Chem 61: 724-733 (2018) Article DOI: 10.1021/acs.jmedchem.7b01249 BindingDB Entry DOI: 10.7270/Q2C24ZV1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Envelope glycoprotein (Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zair...) | BDBM22416 ((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 6.50E+5 | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Binding affinity to Ebola virus Zaire Mayinga-76 recombinant GP protein by SYPRO orange dye-based fluorescence assay | J Med Chem 61: 724-733 (2018) Article DOI: 10.1021/acs.jmedchem.7b01249 BindingDB Entry DOI: 10.7270/Q2C24ZV1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Envelope glycoprotein (Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zair...) | BDBM78577 (BEPRIDIL HYDROCHLORIDE | Bepridil | MLS000028456 |...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.90E+5 | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Binding affinity to Ebola virus Zaire Mayinga-76 recombinant GP protein by SYPRO orange dye-based fluorescence assay | J Med Chem 61: 724-733 (2018) Article DOI: 10.1021/acs.jmedchem.7b01249 BindingDB Entry DOI: 10.7270/Q2C24ZV1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Envelope glycoprotein (Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zair...) | BDBM58492 (2-[4-[(Z)-4-chloranyl-1,2-diphenyl-but-1-enyl]phen...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Binding affinity to Ebola virus Zaire Mayinga-76 recombinant GP protein by SYPRO orange dye-based fluorescence assay | J Med Chem 61: 724-733 (2018) Article DOI: 10.1021/acs.jmedchem.7b01249 BindingDB Entry DOI: 10.7270/Q2C24ZV1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Envelope glycoprotein (Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zair...) | BDBM50028094 ((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 9.50E+5 | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Binding affinity to Ebola virus Zaire Mayinga-76 recombinant GP protein by SYPRO orange dye-based fluorescence assay | J Med Chem 61: 724-733 (2018) Article DOI: 10.1021/acs.jmedchem.7b01249 BindingDB Entry DOI: 10.7270/Q2C24ZV1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |