Affinity Data by PubMed id=29407994

PubMed code 29407994

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50458016 (CHEMBL4217978) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Julius-Maximilians-Universit£t W£rzburg Curated by ChEMBL					Assay Description Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli (DE3) incubated for overnight by Th-S fluorescence staining based UV-Vis...				Eur J Med Chem 146: 93-107 (2018) Article DOI: 10.1016/j.ejmech.2018.01.036 BindingDB Entry DOI: 10.7270/Q28P635R
Julius-Maximilians-Universit£t W£rzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50458015 (CHEMBL4207221) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Julius-Maximilians-Universit£t W£rzburg Curated by ChEMBL					Assay Description Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli (DE3) incubated for overnight by Th-S fluorescence staining based UV-Vis...				Eur J Med Chem 146: 93-107 (2018) Article DOI: 10.1016/j.ejmech.2018.01.036 BindingDB Entry DOI: 10.7270/Q28P635R
Julius-Maximilians-Universit£t W£rzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50458016 (CHEMBL4217978) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Julius-Maximilians-Universit£t W£rzburg Curated by ChEMBL					Assay Description Inhibition of amyloid beta 42 (unknown origin) expressed in Escherichia coli BL21 (DE3) aggregation incubated for overnight by Th-S fluorescence stai...				Eur J Med Chem 146: 93-107 (2018) Article DOI: 10.1016/j.ejmech.2018.01.036 BindingDB Entry DOI: 10.7270/Q28P635R
Julius-Maximilians-Universit£t W£rzburg Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50458015 (CHEMBL4207221) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Julius-Maximilians-Universit£t W£rzburg Curated by ChEMBL					Assay Description Inhibition of amyloid beta 42 (unknown origin) expressed in Escherichia coli BL21 (DE3) aggregation incubated for overnight by Th-S fluorescence stai...				Eur J Med Chem 146: 93-107 (2018) Article DOI: 10.1016/j.ejmech.2018.01.036 BindingDB Entry DOI: 10.7270/Q28P635R
Julius-Maximilians-Universit£t W£rzburg Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%