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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50244503 (CHEMBL4078293) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland Curated by ChEMBL | Assay Description Inhibition of human ERG expressed in CHO cells by automated patch clamp method | J Med Chem 61: 2329-2352 (2018) Article DOI: 10.1021/acs.jmedchem.7b01581 BindingDB Entry DOI: 10.7270/Q2CC133S | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50244503 (CHEMBL4078293) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland Curated by ChEMBL | Assay Description Inhibition of CYP3A4 in human liver microsomes assessed as decrease in formation of 6beta-hydroxytestosterone from testosterone after 10 mins by LC-M... | J Med Chem 61: 2329-2352 (2018) Article DOI: 10.1021/acs.jmedchem.7b01581 BindingDB Entry DOI: 10.7270/Q2CC133S | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
