Affinity Data by PubMed id=29627261

PubMed code 29627261

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50271617 (CHEMBL4129294) Show SMILES CCn1nc(-c2nccs2)c2sccc2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from recombinant human A1 receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting method				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50271641 (CHEMBL4125984) Show SMILES CCn1nc(-c2cccs2)c2sccc2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	724	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from recombinant human A1 receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting method				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50271639 (CHEMBL4129433) Show SMILES CCn1nc(-c2ccccn2)c2sccc2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	782	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from recombinant human A1 receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting method				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50271640 (CHEMBL4128054) Show SMILES CC(C)n1nc(-c2ccccn2)c2sccc2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	912	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from recombinant human A1 receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting method				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50271642 (CHEMBL4126960) Show SMILES O=c1[nH]nc(-c2nccs2)c2sccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from recombinant human A1 receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting method				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50271617 (CHEMBL4129294) Show SMILES CCn1nc(-c2nccs2)c2sccc2c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-ZM241385 from recombinant human A2A receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting me...				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50271638 (CHEMBL4127738) Show SMILES CCn1nc(-c2ccccc2)c2sccc2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.59E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]-ABMECA from recombinant human A3 receptor expressed in CHO cell membranes measured after 120 mins by scintillation counting me...				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50271638 (CHEMBL4127738) Show SMILES CCn1nc(-c2ccccc2)c2sccc2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from recombinant human A1 receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting method				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50271639 (CHEMBL4129433) Show SMILES CCn1nc(-c2ccccn2)c2sccc2c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-ZM241385 from recombinant human A2A receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting me...				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50271618 (CHEMBL4129175) Show SMILES Nn1nc(-c2nccs2)c2sccc2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from recombinant human A1 receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting method				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50271617 (CHEMBL4129294) Show SMILES CCn1nc(-c2nccs2)c2sccc2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]-ABMECA from recombinant human A3 receptor expressed in CHO cell membranes measured after 120 mins by scintillation counting me...				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50271654 (CHEMBL4126814) Show SMILES CCc1nn(CC)c(=O)c2cc(sc12)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-ZM241385 from recombinant human A2A receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting me...				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50271642 (CHEMBL4126960) Show SMILES O=c1[nH]nc(-c2nccs2)c2sccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-ZM241385 from recombinant human A2A receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting me...				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50271653 (CHEMBL4126822) Show SMILES Nn1nc(-c2cccs2)c2sccc2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from recombinant human A1 receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting method				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50271652 (CHEMBL4126789) Show SMILES Nn1nc(-c2ccccn2)c2sccc2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from recombinant human A1 receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting method				Bioorg Med Chem Lett 28: 1484-1489 (2018) Article DOI: 10.1016/j.bmcl.2018.03.086 BindingDB Entry DOI: 10.7270/Q2HD7Z5W
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%