Affinity Data by PubMed id=3009814

PubMed code 3009814

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021340 (CHEMBL166743 \| [(2-Mercapto-propionyl)-p-tolyl-ami...) Show SMILES CC(S)C(=O)N(CC(O)=O)c1ccc(C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021332 (CHEMBL165952 \| [Cyclopentyl-(2-mercapto-propionyl)...) Show SMILES CC(S)C(=O)N(CC(O)=O)C1CCCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021338 (3-(2-Mercapto-propionyl)-thiazolidine-4-carboxylic...) Show SMILES CC(S)C(=O)N1CSC[C@H]1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of activity of rabbit lung Angiotensin I converting enzyme at pH 8.5; 0.14-10				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021338 (3-(2-Mercapto-propionyl)-thiazolidine-4-carboxylic...) Show SMILES CC(S)C(=O)N1CSC[C@H]1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021336 (CHEMBL355163 \| [(2-Acetylsulfanyl-propionyl)-p-tol...) Show SMILES CC(SC(C)=O)C(=O)N(CC(O)=O)c1ccc(C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021333 (CHEMBL167651 \| [(2-Acetylsulfanyl-propionyl)-cyclo...) Show SMILES CC(SC(C)=O)C(=O)N(CC(O)=O)C1CCCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50421739 (CHEMBL2110192) Show SMILES C[C@H](SC(C)=O)C(=O)N1CSC[C@H]1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50020805 ((2-Mercapto-propionylamino)-acetic acid \| CHEMBL13...) Show SMILES CC(S)C(=O)NCC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021343 (2-[(2-Acetylsulfanyl-propionyl)-cyclopentyl-amino]...) Show SMILES CC(SC(C)=O)C(=O)N(C(C)C(O)=O)C1CCCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021339 (2-[Cyclopentyl-(2-mercapto-propionyl)-amino]-propi...) Show SMILES CC(S)C(=O)N(C(C)C(O)=O)C1CCCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021342 (3-(2-Mercapto-propionyl)-2,2,5,5-tetramethyl-thiaz...) Show SMILES CC(S)C(=O)N1C(C(O)=O)C(C)(C)SC1(C)C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50421758 (CHEMBL2110310) Show SMILES C[C@@H](SC(C)=O)C(=O)N1CSC[C@H]1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021341 (2-[(2-Acetylsulfanyl-propionyl)-cyclopentyl-amino]...) Show SMILES CC(SC(C)=O)C(=O)N(C1CCCC1)C(C)(C)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021337 (2-(2-Acetylsulfanyl-propionyl)-3-methyl-1,2,3,4-te...) Show SMILES CC(SC(C)=O)C(=O)N1Cc2ccccc2CC1(C)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50021335 (3-(2-Acetylsulfanyl-propionyl)-2,2,5,5-tetramethyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the activity of rabbit lung Angiotensin I converting enzyme				J Med Chem 29: 784-96 (1986) BindingDB Entry DOI: 10.7270/Q2F47N4B
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%