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PubMed code 30143421

Compile data set for download or QSAR
Found 27 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466974
PNG
(CHEMBL4285413)
Show SMILES CCCCCN(CC1CCN(Cc2ccccc2)CC1)C(C)=O
Show InChI InChI=1S/C20H32N2O/c1-3-4-8-13-22(18(2)23)17-20-11-14-21(15-12-20)16-19-9-6-5-7-10-19/h5-7,9-10,20H,3-4,8,11-17H2,1-2H3
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 17n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466983
PNG
(CHEMBL4277337)
Show SMILES CCN(CC1CCN(Cc2ccc(Cl)cc2Cl)CC1)C(C)=O
Show InChI InChI=1S/C17H24Cl2N2O/c1-3-21(13(2)22)11-14-6-8-20(9-7-14)12-15-4-5-16(18)10-17(15)19/h4-5,10,14H,3,6-9,11-12H2,1-2H3
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 20n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466970
PNG
(CHEMBL4278696)
Show SMILES CCCCCN(CC1CCN(Cc2ccc(Cl)cc2)CC1)C(C)=O
Show InChI InChI=1S/C20H31ClN2O/c1-3-4-5-12-23(17(2)24)16-19-10-13-22(14-11-19)15-18-6-8-20(21)9-7-18/h6-9,19H,3-5,10-16H2,1-2H3
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 32n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466984
PNG
(CHEMBL4284597)
Show SMILES CCCCN(CC1CCN(Cc2ccc(Cl)cc2)CC1)C(C)=O
Show InChI InChI=1S/C19H29ClN2O/c1-3-4-11-22(16(2)23)15-18-9-12-21(13-10-18)14-17-5-7-19(20)8-6-17/h5-8,18H,3-4,9-15H2,1-2H3
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 34n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466976
PNG
(CHEMBL4281986)
Show SMILES CCCN(CC1CCN(Cc2ccccc2)CC1)C(C)=O
Show InChI InChI=1S/C18H28N2O/c1-3-11-20(16(2)21)15-18-9-12-19(13-10-18)14-17-7-5-4-6-8-17/h4-8,18H,3,9-15H2,1-2H3
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 37n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466973
PNG
(CHEMBL4289069)
Show SMILES CC(=O)N(CC1CCCCC1)CC1CCN(Cc2ccc(Cl)cc2Cl)CC1
Show InChI InChI=1S/C22H32Cl2N2O/c1-17(27)26(14-18-5-3-2-4-6-18)15-19-9-11-25(12-10-19)16-20-7-8-21(23)13-22(20)24/h7-8,13,18-19H,2-6,9-12,14-16H2,1H3
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 52n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466982
PNG
(CHEMBL4277464)
Show SMILES CC(=O)N(CC1CCCCC1)CC1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H34N2O/c1-19(25)24(17-21-10-6-3-7-11-21)18-22-12-14-23(15-13-22)16-20-8-4-2-5-9-20/h2,4-5,8-9,21-22H,3,6-7,10-18H2,1H3
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 59n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466972
PNG
(CHEMBL4292596)
Show SMILES CCCCN(CC1CCN(Cc2ccccc2)CC1)C(C)=O
Show InChI InChI=1S/C19H30N2O/c1-3-4-12-21(17(2)22)16-19-10-13-20(14-11-19)15-18-8-6-5-7-9-18/h5-9,19H,3-4,10-16H2,1-2H3
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 67n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466979
PNG
(CHEMBL4285685)
Show SMILES CCCCN(CC1CCN(Cc2ccc(Cl)cc2Cl)CC1)C(C)=O
Show InChI InChI=1S/C19H28Cl2N2O/c1-3-4-9-23(15(2)24)13-16-7-10-22(11-8-16)14-17-5-6-18(20)12-19(17)21/h5-6,12,16H,3-4,7-11,13-14H2,1-2H3
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 76n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466980
PNG
(CHEMBL4294491)
Show SMILES CCCN(CC1CCN(Cc2ccc(Cl)cc2)CC1)C(C)=O
Show InChI InChI=1S/C18H27ClN2O/c1-3-10-21(15(2)22)14-17-8-11-20(12-9-17)13-16-4-6-18(19)7-5-16/h4-7,17H,3,8-14H2,1-2H3
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 77n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466977
PNG
(CHEMBL4287975)
Show SMILES CC(=O)N(CC1CCCCC1)CC1CCN(Cc2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C22H33ClN2O/c1-18(26)25(16-19-5-3-2-4-6-19)17-21-11-13-24(14-12-21)15-20-7-9-22(23)10-8-20/h7-10,19,21H,2-6,11-17H2,1H3
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 95n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466978
PNG
(CHEMBL4284278)
Show SMILES CCN(CC1CCN(Cc2ccccc2)CC1)C(C)=O
Show InChI InChI=1S/C17H26N2O/c1-3-19(15(2)20)14-17-9-11-18(12-10-17)13-16-7-5-4-6-8-16/h4-8,17H,3,9-14H2,1-2H3
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 97n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466975
PNG
(CHEMBL4277744)
Show SMILES CCCN(CC1CCN(Cc2ccc(Cl)cc2Cl)CC1)C(C)=O
Show InChI InChI=1S/C18H26Cl2N2O/c1-3-8-22(14(2)23)12-15-6-9-21(10-7-15)13-16-4-5-17(19)11-18(16)20/h4-5,11,15H,3,6-10,12-13H2,1-2H3
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 143n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466971
PNG
(CHEMBL4281185)
Show SMILES CCCCCN(CC1CCN(Cc2ccc(Cl)cc2Cl)CC1)C(C)=O
Show InChI InChI=1S/C20H30Cl2N2O/c1-3-4-5-10-24(16(2)25)14-17-8-11-23(12-9-17)15-18-6-7-19(21)13-20(18)22/h6-7,13,17H,3-5,8-12,14-15H2,1-2H3
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 187n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466981
PNG
(CHEMBL4283915)
Show SMILES CCN(CC1CCN(Cc2ccc(Cl)cc2)CC1)C(C)=O
Show InChI InChI=1S/C17H25ClN2O/c1-3-20(14(2)21)13-16-8-10-19(11-9-16)12-15-4-6-17(18)7-5-15/h4-7,16H,3,8-13H2,1-2H3
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 228n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50466983
PNG
(CHEMBL4277337)
Show SMILES CCN(CC1CCN(Cc2ccc(Cl)cc2Cl)CC1)C(C)=O
Show InChI InChI=1S/C17H24Cl2N2O/c1-3-21(13(2)22)11-14-6-8-20(9-7-14)12-15-4-5-16(18)10-17(15)19/h4-5,10,14H,3,6-9,11-12H2,1-2H3
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 285n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466978
PNG
(CHEMBL4284278)
Show SMILES CCN(CC1CCN(Cc2ccccc2)CC1)C(C)=O
Show InChI InChI=1S/C17H26N2O/c1-3-19(15(2)20)14-17-9-11-18(12-10-17)13-16-7-5-4-6-8-16/h4-8,17H,3,9-14H2,1-2H3
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 422n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466970
PNG
(CHEMBL4278696)
Show SMILES CCCCCN(CC1CCN(Cc2ccc(Cl)cc2)CC1)C(C)=O
Show InChI InChI=1S/C20H31ClN2O/c1-3-4-5-12-23(17(2)24)16-19-10-13-22(14-11-19)15-18-6-8-20(21)9-7-18/h6-9,19H,3-5,10-16H2,1-2H3
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 825n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466980
PNG
(CHEMBL4294491)
Show SMILES CCCN(CC1CCN(Cc2ccc(Cl)cc2)CC1)C(C)=O
Show InChI InChI=1S/C18H27ClN2O/c1-3-10-21(15(2)22)14-17-8-11-20(12-9-17)13-16-4-6-18(19)7-5-16/h4-7,17H,3,8-14H2,1-2H3
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 987n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466974
PNG
(CHEMBL4285413)
Show SMILES CCCCCN(CC1CCN(Cc2ccccc2)CC1)C(C)=O
Show InChI InChI=1S/C20H32N2O/c1-3-4-8-13-22(18(2)23)17-20-11-14-21(15-12-20)16-19-9-6-5-7-10-19/h5-7,9-10,20H,3-4,8,11-17H2,1-2H3
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 1.12E+3n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466972
PNG
(CHEMBL4292596)
Show SMILES CCCCN(CC1CCN(Cc2ccccc2)CC1)C(C)=O
Show InChI InChI=1S/C19H30N2O/c1-3-4-12-21(17(2)22)16-19-10-13-20(14-11-19)15-18-8-6-5-7-9-18/h5-9,19H,3-4,10-16H2,1-2H3
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 1.26E+3n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466984
PNG
(CHEMBL4284597)
Show SMILES CCCCN(CC1CCN(Cc2ccc(Cl)cc2)CC1)C(C)=O
Show InChI InChI=1S/C19H29ClN2O/c1-3-4-11-22(16(2)23)15-18-9-12-21(13-10-18)14-17-5-7-19(20)8-6-17/h5-8,18H,3-4,9-15H2,1-2H3
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 1.38E+3n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466979
PNG
(CHEMBL4285685)
Show SMILES CCCCN(CC1CCN(Cc2ccc(Cl)cc2Cl)CC1)C(C)=O
Show InChI InChI=1S/C19H28Cl2N2O/c1-3-4-9-23(15(2)24)13-16-7-10-22(11-8-16)14-17-5-6-18(20)12-19(17)21/h5-6,12,16H,3-4,7-11,13-14H2,1-2H3
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 1.84E+3n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466973
PNG
(CHEMBL4289069)
Show SMILES CC(=O)N(CC1CCCCC1)CC1CCN(Cc2ccc(Cl)cc2Cl)CC1
Show InChI InChI=1S/C22H32Cl2N2O/c1-17(27)26(14-18-5-3-2-4-6-18)15-19-9-11-25(12-10-19)16-20-7-8-21(23)13-22(20)24/h7-8,13,18-19H,2-6,9-12,14-16H2,1H3
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
 2.34E+3n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466977
PNG
(CHEMBL4287975)
Show SMILES CC(=O)N(CC1CCCCC1)CC1CCN(Cc2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C22H33ClN2O/c1-18(26)25(16-19-5-3-2-4-6-19)17-21-11-13-24(14-12-21)15-20-7-9-22(23)10-8-20/h7-10,19,21H,2-6,11-17H2,1H3
UniProtKB/SwissProt

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UniChem
Article
PubMed
 2.43E+3n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466975
PNG
(CHEMBL4277744)
Show SMILES CCCN(CC1CCN(Cc2ccc(Cl)cc2Cl)CC1)C(C)=O
Show InChI InChI=1S/C18H26Cl2N2O/c1-3-8-22(14(2)23)12-15-6-9-21(10-7-15)13-16-4-5-17(19)11-18(16)20/h4-5,11,15H,3,6-10,12-13H2,1-2H3
UniProtKB/SwissProt

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UniChem
Article
PubMed
 2.58E+3n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50466971
PNG
(CHEMBL4281185)
Show SMILES CCCCCN(CC1CCN(Cc2ccc(Cl)cc2Cl)CC1)C(C)=O
Show InChI InChI=1S/C20H30Cl2N2O/c1-3-4-5-10-24(16(2)25)14-17-8-11-23(12-9-17)15-18-6-7-19(21)13-20(18)22/h6-7,13,17H,3-5,8-12,14-15H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 3.20E+3n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting

Bioorg Med Chem Lett 28: 3206-3209 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.016
BindingDB Entry DOI: 10.7270/Q2QN69FH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%